| Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia G Skibinski, NJ Parkinson, JM Brown, L Chakrabarti, SL Lloyd, ... Nature genetics 37 (8), 806-808, 2005 | 1000 | 2005 |
| Direct membrane association drives mitochondrial fission by the parkinson disease-associated protein α-Synuclein*♦ K Nakamura, VM Nemani, F Azarbal, G Skibinski, JM Levy, K Egami, ... Journal of Biological Chemistry 286 (23), 20710-20726, 2011 | 702 | 2011 |
| Cytoplasmic mislocalization of TDP-43 is toxic to neurons and enhanced by a mutation associated with familial amyotrophic lateral sclerosis SJ Barmada, G Skibinski, E Korb, EJ Rao, JY Wu, S Finkbeiner Journal of Neuroscience 30 (2), 639-649, 2010 | 607 | 2010 |
| In silico labeling: predicting fluorescent labels in unlabeled images EM Christiansen, SJ Yang, DM Ando, A Javaherian, G Skibinski, S Lipnick, ... Cell 173 (3), 792-803. e19, 2018 | 605 | 2018 |
| ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B) N Parkinson, PG Ince, MO Smith, R Highley, G Skibinski, PM Andersen, ... Neurology 67 (6), 1074-1077, 2006 | 518 | 2006 |
| Mutant LRRK2 toxicity in neurons depends on LRRK2 levels and synuclein but not kinase activity or inclusion bodies G Skibinski, K Nakamura, MR Cookson, S Finkbeiner Journal of Neuroscience 34 (2), 418-433, 2014 | 162 | 2014 |
| Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson’s disease G Toth, SJ Gardai, W Zago, CW Bertoncini, N Cremades, SL Roy, ... PloS one 9 (2), e87133, 2014 | 160 | 2014 |
| Nrf2 mitigates LRRK2-and α-synuclein–induced neurodegeneration by modulating proteostasis G Skibinski, V Hwang, DM Ando, A Daub, AK Lee, A Ravisankar, ... Proceedings of the National Academy of Sciences 114 (5), 1165-1170, 2017 | 113 | 2017 |
| iPS cells in the study of PD molecular pathogenesis MM Cobb, A Ravisankar, G Skibinski, S Finkbeiner Cell and tissue research 373, 61-77, 2018 | 39 | 2018 |
| Drug discovery in Parkinson's disease: update and developments in the use of cellular models G Skibinski, S Finkbeiner International journal of high throughput screening, 15-25, 2011 | 36 | 2011 |
| The E3 ligase TRIM1 ubiquitinates LRRK2 and controls its localization, degradation, and toxicity AED Stormo, F Shavarebi, M FitzGibbon, EM Earley, H Ahrendt, LS Lum, ... Journal of Cell Biology 221 (4), e202010065, 2022 | 18 | 2022 |
| MRC Proteomics in ALS Study N Parkinson, PG Ince, MO Smith, R Highley, G Skibinski, PM Andersen, ... FReJA Consortium ALS phenotypes with mutations in CHMP2B (charged …, 2006 | 18 | 2006 |
| Longitudinal measures of proteostasis in live neurons: features that determine fate in models of neurodegenerative disease G Skibinski, S Finkbeiner FEBS letters 587 (8), 1139-1146, 2013 | 17 | 2013 |
| Frontotemporal dementia linked to chromosome 3 J Brown, S Gydesen, P Johannsen, A Gade, G Skibinski, L Chakrabarti, ... Dementia and geriatric cognitive disorders 17 (4), 274-276, 2004 | 11 | 2004 |
| Optimization and scaling of patient-derived brain organoids uncovers deep phenotypes of disease K Shah, R Bedi, A Rogozhnikov, P Ramkumar, Z Tong, B Rash, M Stanton, ... bioRxiv, 2020.08. 26.251611, 2020 | 9 | 2020 |
| A three-groups model for high-throughput survival screens BA Shaby, G Skibinski, M Ando, ES LaDow, S Finkbeiner Biometrics 72 (3), 936-944, 2016 | 8 | 2016 |
| Generation of two human induced pluripotent stem cell lines from fibroblasts of Parkinson’s disease patients carrying the ILE368ASN mutation in PINK1 (LCSBi002) and the R275W … G Novak, S Finkbeiner, G Skibinski, M Bernini, C Donato, A Skupin Stem Cell Research 61, 102765, 2022 | 3 | 2022 |
| Generation of two human induced pluripotent stem cell lines from fibroblasts of unrelated Parkinson’s patients carrying the G2019S mutation in the LRRK2 gene (LCSBi005, LCSBi006) G Novak, S Finkbeiner, G Skibinski, A Skupin Stem Cell Research 57, 102569, 2021 | 2 | 2021 |
| Preclinical signs of impairment in persons at high risk of frontotemporal dementia related to chromosome 3 (FTD3): preliminary findings in neuropsychological tests A Gade, G Skibinski, S Gydesen Neurobiol Aging 25 (suppl 2), S453, 2004 | 2 | 2004 |
| Neuroimmune cortical organoids overexpressing C4A exhibit multiple schizophrenia endophenotypes MM Stanton, S Modan, PM Taylor, HN Hariani, J Sorokin, BG Rash, ... bioRxiv, 2023.01. 20.524955, 2023 | 1 | 2023 |
