Structural and functional insight into how the Plasmodium falciparum VAR2CSA protein mediates binding to chondroitin sulfate A in placental malaria TM Clausen, S Christoffersen, M Dahlbäck, AE Langkilde, KE Jensen, ... Journal of Biological Chemistry 287 (28), 23332-23345, 2012 | 212 | 2012 |
Methods for structural characterization of prefibrillar intermediates and amyloid fibrils AE Langkilde, B Vestergaard FEBS letters 583 (16), 2600-2609, 2009 | 80 | 2009 |
In-depth analysis of subclass-specific conformational preferences of IgG antibodies X Tian, B Vestergaard, M Thorolfsson, Z Yang, HB Rasmussen, ... IUCrJ 2 (1), 9-18, 2015 | 75 | 2015 |
The architecture of amyloid-like peptide fibrils revealed by X-ray scattering, diffraction and electron microscopy AE Langkilde, KL Morris, LC Serpell, DI Svergun, B Vestergaard Acta Crystallographica Section D: Biological Crystallography 71 (4), 882-895, 2015 | 63 | 2015 |
Small-angle x-ray scattering screening complements conventional biophysical analysis: comparative structural and biophysical analysis of monoclonal antibodies IgG1, IgG2, and IgG4 X Tian, AE Langkilde, M Thorolfsson, HB Rasmussen, B Vestergaard Journal of pharmaceutical sciences 103 (6), 1701-1710, 2014 | 62 | 2014 |
Short strong hydrogen bonds in proteins: a case study of rhamnogalacturonan acetylesterase A Langkilde, SM Kristensen, L Lo Leggio, A Mølgaard, JH Jensen, ... Acta Crystallographica Section D: Biological Crystallography 64 (8), 851-863, 2008 | 61 | 2008 |
Wildtype and A30P mutant alpha-synuclein form different fibril structures SB Nielsen, F Macchi, S Raccosta, AE Langkilde, L Giehm, A Kyrsting, ... PloS one 8 (7), e67713, 2013 | 60 | 2013 |
Protein/lipid coaggregates are formed during α-synuclein-induced disruption of lipid bilayers A van Maarschalkerweerd, V Vetri, AE Langkilde, V Foderà, ... Biomacromolecules 15 (10), 3643-3654, 2014 | 57 | 2014 |
Monoclonal antibodies follow distinct aggregation pathways during production-relevant acidic incubation and neutralization T Skamris, X Tian, M Thorolfsson, HS Karkov, HB Rasmussen, ... Pharmaceutical research 33, 716-728, 2016 | 54 | 2016 |
Refinement of α-synuclein ensembles against SAXS data: Comparison of force fields and methods MC Ahmed, LK Skaanning, A Jussupow, EA Newcombe, BB Kragelund, ... Frontiers in molecular biosciences 8, 654333, 2021 | 50 | 2021 |
Femtosecond X-ray coherent diffraction of aligned amyloid fibrils on low background graphene C Seuring, K Ayyer, E Filippaki, M Barthelmess, JN Longchamp, P Ringler, ... Nature communications 9 (1), 1836, 2018 | 45 | 2018 |
Avidity within the N‐terminal anchor drives α‐synuclein membrane interaction and insertion E Cholak, K Bugge, A Khondker, K Gauger, E Pedraz‐Cuesta, ... The FASEB Journal 34 (6), 7462-7482, 2020 | 29 | 2020 |
Developing Inhibitors of the p47phox–p22phox Protein–Protein Interaction by Fragment-Based Drug Discovery SMØ Solbak, J Zang, D Narayanan, LJ Høj, S Bucciarelli, C Softley, ... Journal of Medicinal Chemistry 63 (3), 1156-1177, 2020 | 27 | 2020 |
Size-Selective Phagocytic Clearance of Fibrillar α-Synuclein through Conformational Activation of Complement Receptor 4 K Juul-Madsen, P Qvist, KL Bendtsen, AE Langkilde, B Vestergaard, ... The Journal of Immunology 204 (5), 1345-1361, 2020 | 26 | 2020 |
Formation of covalent di-tyrosine dimers in recombinant α-synuclein A Van Maarschalkerweerd, MN Pedersen, H Peterson, M Nilsson, ... Intrinsically disordered proteins 3 (1), e1071302, 2015 | 21 | 2015 |
The structural basis of fungal glucuronoyl esterase activity on natural substrates HA Ernst, C Mosbech, AE Langkilde, P Westh, AS Meyer, JW Agger, ... Nature Communications 11 (1), 1026, 2020 | 20 | 2020 |
Insight into Calcium-Binding Motifs of Intrinsically Disordered Proteins EA Newcombe, CB Fernandes, JE Lundsgaard, I Brakti, K Lindorff-Larsen, ... Biomolecules 11 (8), 1173, 2021 | 17 | 2021 |
Structures of three salts of phthalic acid; variation in crystal packing and geometry of the hydrogen phthalate ion A Langkilde, D Madsen, S Larsen Acta Crystallographica Section B: Structural Science 60 (5), 502-511, 2004 | 16 | 2004 |
Structural characterization of prefibrillar intermediates and amyloid fibrils by small-angle X-ray scattering AE Langkilde, B Vestergaard Amyloid Proteins: Methods and Protocols, 137-155, 2012 | 14 | 2012 |
Distinct α-Synuclein: Lipid Co-Structure Complexes Affect Amyloid Nucleation through Fibril Mimetic Behavior E Cholak, S Bucciarelli, K Bugge, NT Johansen, B Vestergaard, L Arleth, ... Biochemistry 58 (50), 5052-5065, 2019 | 13 | 2019 |