Identification of functionally variant MDR1 alleles among European Americans and African Americans RB Kim, BF Leake, EF Choo, GK Dresser, SV Kubba, UI Schwarz, ... Clinical Pharmacology & Therapeutics 70 (2), 189-199, 2001 | 1309 | 2001 |
Genetic determinants of response to warfarin during initial anticoagulation UI Schwarz, MD Ritchie, Y Bradford, C Li, SM Dudek, A Frye-Anderson, ... New England Journal of Medicine 358 (10), 999-1008, 2008 | 775 | 2008 |
Fruit juices inhibit organic anion transporting polypeptide–mediated drug uptake to decrease the oral availability of fexofenadine GK Dresser, DG Bailey, BF Leake, UI Schwarz, PA Dawson, DJ Freeman, ... Clinical pharmacology & therapeutics 71 (1), 11-20, 2002 | 756 | 2002 |
A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose GM Cooper, JA Johnson, TY Langaee, H Feng, IB Stanaway, UI Schwarz, ... Blood, The Journal of the American Society of Hematology 112 (4), 1022-1027, 2008 | 540 | 2008 |
Intestinal drug transporter expression and the impact of grapefruit juice in humans H Glaeser, DG Bailey, GK Dresser, JC Gregor, UI Schwarz, JS McGrath, ... Clinical Pharmacology & Therapeutics 81 (3), 362-370, 2007 | 491 | 2007 |
Identification and functional characterization of a new CYP2C9 variant (CYP2C9* 5) expressed among African Americans LJ Dickmann, AE Rettie, MB Kneller, RB Kim, AJJ Wood, CM Stein, ... Molecular pharmacology 60 (2), 382-387, 2001 | 367 | 2001 |
MDR1 Gene Polymorphisms Affect Therapy Outcome in Acute Myeloid Leukemia Patients T Illmer, US Schuler, C Thiede, UI Schwarz, RB Kim, S Gotthard, D Freund, ... Cancer research 62 (17), 4955-4962, 2002 | 349 | 2002 |
Coordinate induction of both cytochrome P4503A and MDR1 by St John's wort in healthy subjects GK Dresser, UI Schwarz, GR Wilkinson, RB Kim Clinical Pharmacology & Therapeutics 73 (1), 41-50, 2003 | 338 | 2003 |
Human skeletal muscle drug transporters determine local exposure and toxicity of statins MJ Knauer, BL Urquhart, HE Meyer zu Schwabedissen, UI Schwarz, ... Circulation research 106 (2), 297-306, 2010 | 257 | 2010 |
Clinical relevance of genetic polymorphisms in the human CYP2C9 gene UI Schwarz European journal of clinical investigation 33, 23-30, 2003 | 242 | 2003 |
Effect of drug transporter genotypes on pravastatin disposition in European-and African-American participants RH Ho, L Choi, W Lee, G Mayo, UI Schwarz, RG Tirona, DG Bailey, ... Pharmacogenetics and genomics 17 (8), 647-656, 2007 | 219 | 2007 |
Clinical and pharmacogenetic predictors of circulating atorvastatin and rosuvastatin concentrations in routine clinical care MK DeGorter, RG Tirona, UI Schwarz, YH Choi, GK Dresser, N Suskin, ... Circulation: Cardiovascular Genetics 6 (4), 400-408, 2013 | 216 | 2013 |
P-glycoprotein inhibitor erythromycin increases oral bioavailability of talinolol in humans. UI Schwarz, T Gramatté, J Krappweis, R Oertel, W Kirch International journal of clinical pharmacology and therapeutics 38 (4), 161-167, 2000 | 199 | 2000 |
Unwanted pregnancy on self-medication with St John's wort despite hormonal contraception UI Schwarz, B Büschel, W Kirch British journal of clinical pharmacology 55 (1), 112, 2003 | 182 | 2003 |
Grapefruit juice ingestion significantly reduces talinolol bioavailability UI Schwarz, D Seemann, R Oertel, S Miehlke, E Kuhlisch, MF Fromm, ... Clinical Pharmacology & Therapeutics 77 (4), 291-301, 2005 | 173 | 2005 |
Ontogeny of human hepatic and intestinal transporter gene expression during childhood: age matters MG Mooij, UI Schwarz, BAE De Koning, JS Leeder, R Gaedigk, ... Drug Metabolism and Disposition 42 (8), 1268-1274, 2014 | 163 | 2014 |
Breast cancer resistance protein (ABCG2) and drug disposition: intestinal expression, polymorphisms and sulfasalazine as an in vivo probe BL Urquhart, JA Ware, RG Tirona, RH Ho, BF Leake, UI Schwarz, H Zaher, ... Pharmacogenetics and genomics 18 (5), 439-448, 2008 | 158 | 2008 |
Induction of intestinal P‐glycoprotein by St John's wort reduces the oral bioavailability of talinolol UI Schwarz, H Hanso, R Oertel, S Miehlke, E Kuhlisch, H Glaeser, M Hitzl, ... Clinical Pharmacology & Therapeutics 81 (5), 669-678, 2007 | 157 | 2007 |
Prospective evaluation of a pharmacogenetics-guided warfarin loading and maintenance dose regimen for initiation of therapy IY Gong, RG Tirona, UI Schwarz, N Crown, GK Dresser, S LaRue, ... Blood, The Journal of the American Society of Hematology 118 (11), 3163-3171, 2011 | 114 | 2011 |
Clinical and genetic determinants of warfarin pharmacokinetics and pharmacodynamics during treatment initiation IY Gong, UI Schwarz, N Crown, GK Dresser, A Lazo-Langner, GY Zou, ... Plos one 6 (11), e27808, 2011 | 104 | 2011 |