| Sequence-specific cleavage of double helical DNA by triple helix formation HE Moser, PB Dervan Science 238 (4827), 645-650, 1987 | 1773 | 1987 |
| Physicochemical properties of antibacterial compounds: implications for drug discovery R O’Shea, HE Moser Journal of medicinal chemistry 51 (10), 2871-2878, 2008 | 725 | 2008 |
| Matrix-assisted laser desorption ionization time-of-flight mass spectrometry: a powerful tool for the mass and sequence analysis of natural and modified oligonucleotides U Pieles, W Zürcher, M Schär, H Moser Nucleic acids research 21 (14), 3191-3196, 1993 | 690 | 1993 |
| Antisense oligonucleotides A De Mesmaeker, R Haener, P Martin, HE Moser Accounts of Chemical Research 28 (9), 366-374, 1995 | 618 | 1995 |
| Towards the sustainable discovery and development of new antibiotics M Miethke, M Pieroni, T Weber, M Brönstrup, P Hammann, L Halby, ... Nature Reviews Chemistry 5 (10), 726-749, 2021 | 574 | 2021 |
| Synthesis and spectrum of the neoglycoside ACHN-490 JB Aggen, ES Armstrong, AA Goldblum, P Dozzo, MS Linsell, MJ Gliedt, ... Antimicrobial agents and chemotherapy 54 (11), 4636-4642, 2010 | 269 | 2010 |
| Second generation of antisense oligonucleotides: from nuclease resistance to biological efficacy in animals KH Altmann, NM Dean, D Fabbro, SM Freier, T Geiger, R Hanera, ... CHIMIA International Journal for Chemistry 50 (4), 168-176, 1996 | 251 | 1996 |
| Sequence-specific antitumor activity of a phosphorothioate oligodeoxyribonucleotide targeted to human C-raf kinase supports an antisense mechanism of action in vivo BP Monia, H Sasmor, JF Johnston, SM Freier, EA Lesnik, M Muller, ... Proceedings of the National Academy of Sciences 93 (26), 15481-15484, 1996 | 209 | 1996 |
| Methods of treating infection by drug resistant bacteria H Moser, E Baird, R Burli, Y Ge, S White US Patent App. 10/244,142, 2003 | 194 | 2003 |
| Dual recognition of double‐stranded DNA by 2′‐aminoethoxy‐modified oligonucleotides B Cuenoud, F Casset, D Hüsken, F Natt, RM Wolf, KH Altmann, P Martin, ... Angewandte Chemie International Edition 37 (9), 1288-1291, 1998 | 180 | 1998 |
| DNA binding ligands targeting drug-resistant Gram-positive bacteria. Part 1: Internal benzimidazole derivatives RW Bürli, D McMinn, JA Kaizerman, W Hu, Y Ge, Q Pack, V Jiang, ... Bioorganic & medicinal chemistry letters 14 (5), 1253-1257, 2004 | 152 | 2004 |
| Double strand cleavage of genomic DNA at a single site by triple helix formation SA Strobel, HE Moser, PB Dervan Journal of the American Chemical Society 110 (23), 7927-7929, 1988 | 144 | 1988 |
| Efficient sequence-specific cleavage of RNA using novel europium complexes conjugated to oligonucleotides J Hall, D Hüsken, U Pieles, HE Moser, R Häner Chemistry & Biology 1 (3), 185-190, 1994 | 138 | 1994 |
| Creating RNA bulges: cleavage of RNA in RNA/DNA duplexes by metal ion catalysis D Hüsken, G Goodall, MJJ Blommers, W Jahnke, J Hall, R Häner, ... Biochemistry 35 (51), 16591-16600, 1996 | 113 | 1996 |
| The Identification of Indacaterol as an Ultralong-Acting Inhaled β2-Adrenoceptor Agonist F Baur, D Beattie, D Beer, D Bentley, M Bradley, I Bruce, SJ Charlton, ... Journal of medicinal chemistry 53 (9), 3675-3684, 2010 | 110 | 2010 |
| DNA binding ligands targeting drug-resistant bacteria: structure, activity, and pharmacology JA Kaizerman, MI Gross, Y Ge, S White, W Hu, JX Duan, EE Baird, ... Journal of medicinal chemistry 46 (18), 3914-3929, 2003 | 95 | 2003 |
| DNA binding ligands targeting drug-resistant Gram-positive bacteria. Part 2: C-terminal benzimidazoles and derivatives RW Bürli, P Jones, D McMinn, Q Le, JX Duan, JA Kaizerman, ... Bioorganic & medicinal chemistry letters 14 (5), 1259-1263, 2004 | 82 | 2004 |
| Macrocyclic inhibitors for peptide deformylase: a structure− activity relationship study of the ring size X Hu, KT Nguyen, VC Jiang, D Lofland, HE Moser, D Pei Journal of medicinal chemistry 47 (20), 4941-4949, 2004 | 74 | 2004 |
| New aminoglycoside antibiotics P Dozzo, HE Moser Expert opinion on therapeutic patents 20 (10), 1321-1341, 2010 | 70 | 2010 |
| Optimization of LpxC inhibitors for antibacterial activity and cardiovascular safety F Cohen, JB Aggen, LD Andrews, Z Assar, J Boggs, T Choi, P Dozzo, ... ChemMedChem 14 (16), 1560-1572, 2019 | 69 | 2019 |
