Timo D. Müller
Timo D. Müller
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Glucagon-like peptide 1 (GLP-1)
TD Müller, B Finan, SR Bloom, D D'Alessio, DJ Drucker, PR Flatt, ...
Molecular metabolism 30, 72-130, 2019
Ghrelin. Mol Metab 4: 437–460
TD Müller, R Nogueiras, ML Andermann, ZB Andrews, SD Anker, ...
A guide to analysis of mouse energy metabolism
MH Tschöp, JR Speakman, JRS Arch, J Auwerx, JC Brüning, L Chan, ...
Nature methods 9 (1), 57-63, 2012
Animal models of obesity and diabetes mellitus
M Kleinert, C Clemmensen, SM Hofmann, MC Moore, S Renner, ...
Nature Reviews Endocrinology 14 (3), 140-162, 2018
Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants
A Hinney, TT Nguyen, A Scherag, S Friedel, G Brönner, TD Müller, ...
PloS one 2 (12), e1361, 2007
A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents
B Finan, B Yang, N Ottaway, DL Smiley, T Ma, C Clemmensen, ...
Nature medicine 21 (1), 27-36, 2015
Unimolecular dual incretins maximize metabolic benefits in rodents, monkeys, and humans
B Finan, T Ma, N Ottaway, TD Müller, KM Habegger, KM Heppner, ...
Science translational medicine 5 (209), 209ra151-209ra151, 2013
Anti-obesity drug discovery: advances and challenges
TD Müller, M Blüher, MH Tschöp, RD DiMarchi
Nature Reviews Drug Discovery 21 (3), 201-223, 2022
Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups
A Scherag, C Dina, A Hinney, V Vatin, S Scherag, CIG Vogel, TD Müller, ...
PLoS genetics 6 (4), e1000916, 2010
The new biology and pharmacology of glucagon
TD Müller, B Finan, C Clemmensen, RD DiMarchi, MH Tschöp
Physiological reviews 97 (2), 721-766, 2017
Alternatively activated macrophages do not synthesize catecholamines or contribute to adipose tissue adaptive thermogenesis
K Fischer, HH Ruiz, K Jhun, B Finan, DJ Oberlin, V Van Der Heide, ...
Nature medicine 23 (5), 623-630, 2017
Targeted estrogen delivery reverses the metabolic syndrome
B Finan, B Yang, N Ottaway, K Stemmer, TD Müller, CX Yi, K Habegger, ...
Nature medicine 18 (12), 1847-1856, 2012
Gut-brain cross-talk in metabolic control
C Clemmensen, TD Müller, SC Woods, HR Berthoud, RJ Seeley, ...
Cell 168 (5), 758-774, 2017
The role of leptin in anorexia nervosa: clinical implications
J Hebebrand, TD Muller, K Holtkamp, B Herpertz-Dahlmann
Molecular psychiatry 12 (1), 23-35, 2007
Fibroblast growth factor 21 mediates specific glucagon actions
KM Habegger, K Stemmer, C Cheng, TD Müller, KM Heppner, N Ottaway, ...
Diabetes 62 (5), 1453-1463, 2013
Unimolecular polypharmacy for treatment of diabetes and obesity
MH Tschöp, B Finan, C Clemmensen, V Gelfanov, D Perez-Tilve, ...
Cell metabolism 24 (1), 51-62, 2016
Plasma proteome profiling discovers novel proteins associated with non‐alcoholic fatty liver disease
L Niu, PE Geyer, NJ Wewer Albrechtsen, LL Gluud, A Santos, S Doll, ...
Molecular systems biology 15 (3), e8793, 2019
Ghrelin regulation of glucose metabolism
AL Poher, MH Tschöp, TD Müller
Peptides 100, 236-242, 2018
Chemical hybridization of glucagon and thyroid hormone optimizes therapeutic impact for metabolic disease
B Finan, C Clemmensen, Z Zhu, K Stemmer, K Gauthier, L Müller, ...
Cell 167 (3), 843-857. e14, 2016
Restoration of leptin responsiveness in diet‐induced obese mice using an optimized leptin analog in combination with exendin‐4 or FGF21
TD Müller, LM Sullivan, K Habegger, CX Yi, D Kabra, E Grant, N Ottaway, ...
Journal of Peptide Science 18 (6), 383-393, 2012
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