| E-CRISP: fast CRISPR target site identification F Heigwer, G Kerr, M Boutros Nature methods 11 (2), 122-123, 2014 | 970 | 2014 |
| Data-analysis strategies for image-based cell profiling JC Caicedo, S Cooper, F Heigwer, S Warchal, P Qiu, C Molnar, ... Nature methods 14 (9), 849-863, 2017 | 668 | 2017 |
| Microscopy-based high-content screening M Boutros, F Heigwer, C Laufer Cell 163 (6), 1314-1325, 2015 | 415 | 2015 |
| SARS-CoV-2 infection induces a pro-inflammatory cytokine response through cGAS-STING and NF-κB CJ Neufeldt, B Cerikan, M Cortese, J Frankish, JY Lee, ... Communications biology 5 (1), 45, 2022 | 231 | 2022 |
| RNA Interference (RNAi) Screening in Drosophila F Heigwer, F Port, M Boutros Genetics 208 (3), 853-874, 2018 | 164 | 2018 |
| Machine learning and image-based profiling in drug discovery C Scheeder, F Heigwer, M Boutros Current opinion in systems biology 10, 43-52, 2018 | 163 | 2018 |
| A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila F Port, C Strein, M Stricker, B Rauscher, F Heigwer, J Zhou, ... Elife 9, e53865, 2020 | 136 | 2020 |
| CRISPR library designer (CLD): software for multispecies design of single guide RNA libraries F Heigwer, T Zhan, M Breinig, J Winter, D Brügemann, S Leible, ... Genome biology 17, 1-10, 2016 | 89 | 2016 |
| GenomeCRISPR-a database for high-throughput CRISPR/Cas9 screens B Rauscher, F Heigwer, M Breinig, J Winter, M Boutros Nucleic acids research, gkw997, 2016 | 85 | 2016 |
| E-TALEN: a web tool to design TALENs for genome engineering F Heigwer, G Kerr, N Walther, K Glaeser, O Pelz, M Breinig, M Boutros Nucleic acids research 41 (20), e190-e190, 2013 | 83 | 2013 |
| Toward an integrated map of genetic interactions in cancer cells B Rauscher, F Heigwer, L Henkel, T Hielscher, O Voloshanenko, ... Molecular Systems Biology 14 (2), 2018 | 80 | 2018 |
| caRpools: an R package for exploratory data analysis and documentation of pooled CRISPR/Cas9 screens J Winter, M Breinig, F Heigwer, D Brügemann, S Leible, O Pelz, T Zhan, ... Bioinformatics 32 (4), 632-634, 2016 | 66 | 2016 |
| CRISPRAnalyzeR: Interactive analysis, annotation and documentation of pooled CRISPR screens J Winter, M Schwering, O Pelz, B Rauscher, T Zhan, F Heigwer, M Boutros BioRxiv, 109967, 2017 | 53 | 2017 |
| Acetic acid treatment in S. cerevisiae creates significant energy deficiency and nutrient starvation that is dependent on the activity of the mitochondrial … A Kitanovic, F Bonowski, F Heigwer, P Ruoff, I Kitanovic, C Ungewiss, ... Frontiers in oncology 2, 118, 2012 | 28 | 2012 |
| Time-resolved mapping of genetic interactions to model rewiring of signaling pathways F Heigwer, C Scheeder, T Miersch, B Schmitt, C Blass, MV Pour Jamnani, ... Elife 7, e40174, 2018 | 22 | 2018 |
| Microarray‐based kinetic colorimetric detection for quantitative multiplex protein phosphorylation analysis P Holenya, I Kitanovic, F Heigwer, S Wölfl Proteomics 11 (10), 2129-2133, 2011 | 14 | 2011 |
| Enhanced SARS-CoV-2 entry via UPR-dependent AMPK-related kinase NUAK2 V Prasad, B Cerikan, Y Stahl, K Kopp, V Magg, N Acosta-Rivero, H Kim, ... Molecular Cell 83 (14), 2559-2577. e8, 2023 | 13 | 2023 |
| KOMA: ELISA-microarray calibration and data analysis based on kinetic signal amplification P Holenya, F Heigwer, S Wölfl Journal of immunological methods 380 (1-2), 10-15, 2012 | 10 | 2012 |
| Aged intestinal stem cells propagate cell-intrinsic sources of inflammaging in mice MC Funk, JG Gleixner, F Heigwer, D Vonficht, E Valentini, Z Aydin, ... Developmental Cell 58 (24), 2914-2929. e7, 2023 | 6* | 2023 |
| A global genetic interaction network by single-cell imaging and machine learning F Heigwer, C Scheeder, J Bageritz, S Yousefian, B Rauscher, C Laufer, ... Cell Systems 14 (5), 346-362. e6, 2023 | 5 | 2023 |
Michael BoutrosGerman Cancer Research Center (DKFZ) and Heidelberg UniversityVerified email at dkfz.de
