| Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits SW Min, X Chen, TE Tracy, Y Li, Y Zhou, C Wang, K Shirakawa, ... Nature medicine 21 (10), 1154-1162, 2015 | 479 | 2015 |
| BAG3 is a modular, scaffolding protein that physically links heat shock protein 70 (Hsp70) to the small heat shock proteins JN Rauch, E Tse, R Freilich, SA Mok, LN Makley, DR Southworth, ... Journal of molecular biology 429 (1), 128-141, 2017 | 137 | 2017 |
| Mapping interactions with the chaperone network reveals factors that protect against tau aggregation SA Mok, C Condello, R Freilich, A Gillies, T Arhar, J Oroz, H Kadavath, ... Nature structural & molecular biology 25 (5), 384-393, 2018 | 133 | 2018 |
| Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration TE Tracy, J Madero-Pérez, DL Swaney, TS Chang, M Moritz, C Konrad, ... Cell 185 (4), 712-728. e14, 2022 | 130 | 2022 |
| Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy C Wang, L Fan, RR Khawaja, B Liu, L Zhan, L Kodama, M Chin, Y Li, D Le, ... Nature communications 13 (1), 1969, 2022 | 129 | 2022 |
| Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation JJ Chen, DL Nathaniel, P Raghavan, M Nelson, R Tian, E Tse, JY Hong, ... Journal of Biological Chemistry 294 (50), 18952-18966, 2019 | 113 | 2019 |
| SIRT1 deacetylates tau and reduces pathogenic tau spread in a mouse model of tauopathy SW Min, PD Sohn, Y Li, N Devidze, JR Johnson, NJ Krogan, E Masliah, ... Journal of Neuroscience 38 (15), 3680-3688, 2018 | 112 | 2018 |
| Pathogenic tau impairs axon initial segment plasticity and excitability homeostasis PD Sohn, CTL Huang, R Yan, L Fan, TE Tracy, CM Camargo, ... Neuron 104 (3), 458-470. e5, 2019 | 102 | 2019 |
| Competing protein-protein interactions regulate binding of Hsp27 to its client protein tau R Freilich, M Betegon, E Tse, SA Mok, O Julien, DA Agard, ... Nature communications 9 (1), 4563, 2018 | 89 | 2018 |
| Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy X Chen, Y Li, C Wang, Y Tang, SA Mok, RM Tsai, JC Rojas, A Karydas, ... Molecular neurodegeneration 15, 1-19, 2020 | 75 | 2020 |
| Production of compartmented cultures of rat sympathetic neurons RB Campenot, K Lund, SA Mok Nature protocols 4 (12), 1869-1887, 2009 | 75 | 2009 |
| A retrograde apoptotic signal originating in NGF-deprived distal axons of rat sympathetic neurons in compartmented cultures SA Mok, K Lund, RB Campenot Cell research 19 (5), 546-560, 2009 | 67 | 2009 |
| Tau activation of microglial cGAS–IFN reduces MEF2C-mediated cognitive resilience JC Udeochu, S Amin, Y Huang, L Fan, ERS Torres, GK Carling, B Liu, ... Nature neuroscience 26 (5), 737-750, 2023 | 49 | 2023 |
| A nerve growth factor-induced retrograde survival signal mediated by mechanisms downstream of TrkA SA Mok, RB Campenot Neuropharmacology 52 (2), 270-278, 2007 | 34 | 2007 |
| Pathologic tau conformer ensembles induce dynamic, liquid-liquid phase separation events at the nuclear envelope SG Kang, ZZ Han, N Daude, E McNamara, S Wohlgemuth, ... BMC biology 19, 1-21, 2021 | 25 | 2021 |
| Therapeutic strategies for restoring tau homeostasis ZT Young, SA Mok, JE Gestwicki Cold Spring Harbor perspectives in medicine 8 (1), a024612, 2018 | 23 | 2018 |
| High‐Throughput Screen of Natural Product Extracts in A Yeast Model of Polyglutamine Proteotoxicity GM Walter, A Raveh, SA Mok, TJ McQuade, CJ Arevang, PJ Schultz, ... Chemical biology & drug design 83 (4), 440-449, 2014 | 20 | 2014 |
| Prion-like propagation mechanisms in tauopathies and traumatic brain injury: Challenges and prospects H Alyenbaawi, WT Allison, SA Mok Biomolecules 10 (11), 1487, 2020 | 10 | 2020 |
| A HaloTag® method for assessing the retrograde axonal transport of the p75 neurotrophin receptor and other proteins in compartmented cultures of rat sympathetic … SA Mok, K Lund, P LaPointe, RB Campenot Journal of neuroscience methods 214 (1), 91-104, 2013 | 10 | 2013 |
| Tau conformers in FTLD-MAPT undergo liquid-liquid phase separation and perturb the nuclear envelope SG Kang, ZZ Han, N Daude, E McNamara, S Wohlgemuth, JG Safar, ... bioRxiv, 2020.07. 04.187997, 2020 | 7 | 2020 |
Jason E. GestwickiUniversity of California San FranciscoBestätigte E-Mail-Adresse bei ucsf.edu
