Melissa Graewert
Melissa Graewert
EMBL Hamburg
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Versatile sample environments and automation for biological solution X-ray scattering experiments at the P12 beamline (PETRA III, DESY)
CE Blanchet, A Spilotros, F Schwemmer, MA Graewert, A Kikhney, ...
Journal of applied crystallography 48 (2), 431-443, 2015
The architecture of functional modules in the Hsp90 co‐chaperone Sti1/Hop
AB Schmid, S Lagleder, MA Gräwert, A Röhl, F Hagn, SK Wandinger, ...
The EMBO journal 31 (6), 1506-1517, 2012
Impact and progress in small and wide angle X-ray scattering (SAXS and WAXS)
MA Graewert, DI Svergun
Current opinion in structural biology 23 (5), 748-754, 2013
Preparing monodisperse macromolecular samples for successful biological small-angle X-ray and neutron-scattering experiments
CM Jeffries, MA Graewert, CE Blanchet, DB Langley, AE Whitten, ...
Nature protocols 11 (11), 2122-2153, 2016
Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2
TF Custódio, H Das, DJ Sheward, L Hanke, S Pazicky, J Pieprzyk, ...
Nature communications 11 (1), 1-11, 2020
Limiting radiation damage for high-brilliance biological solution scattering: practical experience at the EMBL P12 beamline PETRAIII
CM Jeffries, MA Graewert, DI Svergun, CE Blanchet
Journal of synchrotron radiation 22 (2), 273-279, 2015
The structural analysis of shark IgNAR antibodies reveals evolutionary principles of immunoglobulins
MJ Feige, MA Gräwert, M Marcinowski, J Hennig, J Behnke, D Ausländer, ...
Proceedings of the National Academy of Sciences 111 (22), 8155-8160, 2014
Automated pipeline for purification, biophysical and x-ray analysis of biomacromolecular solutions
MA Graewert, D Franke, CM Jeffries, CE Blanchet, D Ruskule, K Kuhle, ...
Scientific reports 5, 10734, 2015
High-resolution structures of the IgM Fc domains reveal principles of its hexamer formation
R Müller, MA Gräwert, T Kern, T Madl, J Peschek, M Sattler, M Groll, ...
Proceedings of the National Academy of Sciences 110 (25), 10183-10188, 2013
Gene duplication of the eight-stranded β-barrel OmpX produces a functional pore: a scenario for the evolution of transmembrane β-barrels
T Arnold, M Poynor, S Nussberger, AN Lupas, D Linke
Journal of molecular biology 366 (4), 1174-1184, 2007
Exploiting nature's rich source of proteasome inhibitors as starting points in drug development
MA Gräwert, M Groll
Chemical Communications 48 (10), 1364-1378, 2012
High-level expression, refolding and probing the natural fold of the human voltage-dependent anion channel isoforms I and II
H Engelhardt, T Meins, M Poynor, V Adams, S Nussberger, W Welte, ...
Journal of Membrane Biology 216 (2), 93-105, 2007
Adding Size Exclusion Chromatography (SEC) and Light Scattering (LS) Devices to Obtain High-Quality Small Angle X-Ray Scattering (SAXS) Data
MA Graewert, S Da Vela, TW Gräwert, DS Molodenskiy, CE Blanchet, ...
Crystals 10 (11), 975, 2020
LabDisk for SAXS: a centrifugal microfluidic sample preparation platform for small-angle X-ray scattering
F Schwemmer, CE Blanchet, A Spilotros, D Kosse, S Zehnle, ...
Lab on a Chip 16 (7), 1161-1170, 2016
Elucidation of the α‐Keto‐Aldehyde Binding Mechanism: A Lead Structure Motif for Proteasome Inhibition
MA Gräwert, N Gallastegui, M Stein, B Schmidt, PM Kloetzel, R Huber, ...
Angewandte Chemie International Edition 50 (2), 542-544, 2011
Characterization of mAb dimers reveals predominant dimer forms common in therapeutic mAbs
F Plath, P Ringler, A Graff-Meyer, H Stahlberg, ME Lauer, AC Rufer, ...
MAbs 8 (5), 928-940, 2016
Structural basis for antigen recognition by transglutaminase 2-specific autoantibodies in celiac disease
X Chen, K Hnida, MA Graewert, JT Andersen, R Iversen, A Tuukkanen, ...
Journal of Biological Chemistry 290 (35), 21365-21375, 2015
Smaller capillaries improve the small-angle X-ray scattering signal and sample consumption for biomacromolecular solutions
MA Schroer, CE Blanchet, AY Gruzinov, MA Gräwert, ME Brennich, ...
Journal of synchrotron radiation 25 (4), 1113-1122, 2018
Dynamics of the preprotein translocation channel of the outer membrane of mitochondria
M Poynor, R Eckert, S Nussberger
Biophysical journal 95 (3), 1511-1522, 2008
Reconstruction of quaternary structure from X-ray scattering by equilibrium mixtures of biological macromolecules
MV Petoukhov, IML Billas, M Takacs, MA Graewert, D Moras, DI Svergun
Biochemistry 52 (39), 6844-6855, 2013
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