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Senta Kapnick
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Cytochrome c oxidase activity is a metabolic checkpoint that regulates cell fate decisions during T cell activation and differentiation
TN Tarasenko, SE Pacheco, MK Koenig, J Gomez-Rodriguez, ...
Cell metabolism 25 (6), 1254-1268. e7, 2017
1422017
Cortical actin recovery at the immunological synapse leads to termination of lytic granule secretion in cytotoxic T lymphocytes
AT Ritter, SM Kapnick, S Murugesan, PL Schwartzberg, GM Griffiths, ...
Proceedings of the National Academy of Sciences 114 (32), E6585-E6594, 2017
952017
Discoidin domain receptor 2 regulates neutrophil chemotaxis in 3D collagen matrices
PV Afonso, CP McCann, SM Kapnick, CA Parent
Blood, The Journal of the American Society of Hematology 121 (9), 1644-1650, 2013
782013
The emerging role of immune dysfunction in mitochondrial diseases as a paradigm for understanding immunometabolism
SM Kapnick, SE Pacheco, PJ McGuire
Metabolism 81, 97-112, 2018
582018
Inducible T cell kinase regulates the acquisition of cytolytic capacity and degranulation in CD8+ CTLs
SM Kapnick, JC Stinchcombe, GM Griffiths, PL Schwartzberg
The Journal of Immunology 198 (7), 2699-2711, 2017
482017
Inhibition of diacylglycerol kinase α restores restimulation-induced cell death and reduces immunopathology in XLP-1
E Ruffo, V Malacarne, SE Larsen, R Das, L Patrussi, C Wülfing, C Biskup, ...
Science translational medicine 8 (321), 321ra7-321ra7, 2016
472016
Application of bioluminescence imaging to the prediction of lethality in vaccinia virus-infected mice
M Zaitseva, SM Kapnick, J Scott, LR King, J Manischewitz, L Sirota, ...
Journal of virology 83 (20), 10437-10447, 2009
462009
Genetic Defects in Phosphoinositide 3-Kinase δ Influence CD8+ T Cell Survival, Differentiation, and Function
JL Cannons, S Preite, SM Kapnick, G Uzel, PL Schwartzberg
Frontiers in Immunology 9, 1758, 2018
332018
New tuberculosis drug development: targeting the shikimate pathway
SM Kapnick, Y Zhang
Expert Opinion on Drug Discovery 3 (5), 565-577, 2008
272008
Polyclonal antibody cocktails generated using DNA vaccine technology protect in murine models of orthopoxvirus disease
JW Golden, M Zaitseva, S Kapnick, RW Fisher, MG Mikolajczyk, ...
Virology Journal 8, 1-19, 2011
252011
Passive immunotherapies protect WRvFire and IHD-J-Luc vaccinia virus-infected mice from lethality by reducing viral loads in the upper respiratory tract and internal organs
M Zaitseva, SM Kapnick, CA Meseda, E Shotwell, LR King, ...
Journal of virology 85 (17), 9147-9158, 2011
192011
Mapping the mechanical and immunological profiles of polymeric microneedles to enable vaccine and immunotherapy applications
SA Shah, RS Oakes, SM Kapnick, CM Jewell
Frontiers in immunology 13, 843355, 2022
182022
Exploiting rational assembly to map distinct roles of regulatory cues during autoimmune therapy
RS Oakes, LH Tostanoski, SM Kapnick, E Froimchuk, SK Black, X Zeng, ...
ACS nano 15 (3), 4305-4320, 2021
142021
The nanoparticle-enabled success of COVID-19 mRNA vaccines and the promise of microneedle platforms for pandemic vaccine response
SM Kapnick
DNA and Cell Biology 41 (1), 25-29, 2022
132022
PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory
JL Cannons, AV Villarino, SM Kapnick, S Preite, HY Shih, ...
Cell reports 37 (2), 2021
132021
Biophysical properties of self-assembled immune signals impact signal processing and the nature of regulatory immune function
E Froimchuk, RS Oakes, SM Kapnick, AA Yanes, CM Jewell
Nano letters 21 (9), 3762-3771, 2021
122021
Measurements of vaccinia virus dissemination using whole body imaging: approaches for predicting of lethality in challenge models and testing of vaccines and antiviral treatments
M Zaitseva, S Kapnick, H Golding
Vaccinia Virus and Poxvirology: Methods and Protocols, 161-176, 2012
112012
Self‐Assembly of Immune Signals to Program Innate Immunity through Rational Adjuvant Design
ML Bookstaver, Q Zeng, RS Oakes, SM Kapnick, V Saxena, C Edwards, ...
Advanced Science 10 (1), 2202393, 2023
102023
Mitochondrial disease disrupts hepatic allostasis and lowers the threshold for immune-mediated liver toxicity
M Jestin, SM Kapnick, TN Tarasenko, CT Burke, PM Zerfas, F Diaz, ...
Molecular Metabolism 37, 100981, 2020
72020
Mitochondrial Physiology
E Gnaiger
The many Faces 158, 2005
7*2005
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