| Regio-and stereoselectivity of P450-catalysed hydroxylation of steroids controlled by laboratory evolution S Kille, FE Zilly, JP Acevedo, MT Reetz Nature Chemistry 3 (9), 738-743, 2011 | 397 | 2011 |
| Reducing codon redundancy and screening effort of combinatorial protein libraries created by saturation mutagenesis S Kille, CG Acevedo-Rocha, LP Parra, ZG Zhang, DJ Opperman, ... ACS synthetic biology 2 (2), 83-92, 2013 | 361 | 2013 |
| Directed evolution of an enantioselective enoate‐reductase: testing the utility of iterative saturation mutagenesis DJ Bougioukou, S Kille, A Taglieber, MT Reetz Advanced synthesis & catalysis 351 (18), 3287-3305, 2009 | 208 | 2009 |
| Improved PCR method for the creation of saturation mutagenesis libraries in directed evolution: application to difficult-to-amplify templates J Sanchis, L Fernández, JD Carballeira, J Drone, Y Gumulya, ... Applied microbiology and biotechnology 81, 387-397, 2008 | 155 | 2008 |
| P450-catalyzed regio-and diastereoselective steroid hydroxylation: efficient directed evolution enabled by mutability landscaping CG Acevedo-Rocha, CG Gamble, R Lonsdale, A Li, N Nett, ... ACS Catalysis 8 (4), 3395-3410, 2018 | 138 | 2018 |
| Iterative saturation mutagenesis: a powerful approach to engineer proteins by systematically simulating Darwinian evolution CG Acevedo-Rocha, S Hoebenreich, MT Reetz Directed evolution library creation: Methods and protocols, 103-128, 2014 | 103 | 2014 |
| Pervasive cooperative mutational effects on multiple catalytic enzyme traits emerge via long-range conformational dynamics CG Acevedo-Rocha, A Li, L D’Amore, S Hoebenreich, J Sanchis, ... Nature Communications 12 (1), 1621, 2021 | 80 | 2021 |
| Speeding up directed evolution: Combining the advantages of solid-phase combinatorial gene synthesis with statistically guided reduction of screening effort S Hoebenreich, FE Zilly, CG Acevedo-Rocha, M Zilly, MT Reetz ACS synthetic biology 4 (3), 317-331, 2015 | 51 | 2015 |
| Bioorthogonal enzymatic activation of caged compounds C Ritter, N Nett, CG Acevedo‐Rocha, R Lonsdale, K Kräling, F Dempwolff, ... Angewandte Chemie International Edition 54 (45), 13440-13443, 2015 | 47 | 2015 |
| Directed Evolution of an FeII-Dependent Halogenase for Asymmetric C(sp3)–H Chlorination S Duewel, L Schmermund, T Faber, K Harms, V Srinivasan, E Meggers, ... ACS Catalysis 10 (2), 1272-1277, 2019 | 41 | 2019 |
| Revealing Additional Stereocomplementary Pairs of Old Yellow Enzymes by Rational Transfer of Engineered Residues N Nett, S Duewel, AA Richter, S Hoebenreich ChemBioChem, 2017 | 32 | 2017 |
| A robust and stereocomplementary panel of ene-reductase variants for gram-scale asymmetric hydrogenation N Nett, S Duewel, L Schmermund, GE Benary, K Ranaghan, A Mulholland, ... Molecular Catalysis 502, 111404, 2021 | 18 | 2021 |
| Flavoproteins in directed evolution S Kille | 9 | 2011 |
| Bioorthogonale enzymatische Aktivierung maskierter Verbindungen C Ritter, N Nett, CG Acevedo‐Rocha, R Lonsdale, K Kräling, F Dempwolff, ... Angewandte Chemie 127 (45), 13640-13644, 2015 | 4 | 2015 |
| Laboratory-Scale Hydroxylation of Steroids by P450BM3 Variants S Hoebenreich, M Spinck, N Nett Microbial Steroids: Methods and Protocols, 239-257, 2017 | 2 | 2017 |
| Protein Engineering: Development of Novel Enzymes for the Improved Reduction of C=C Double Bonds S Kille, MT Reetz Synthetic Methods for Biologically Active Molecules: Exploring the Potential …, 2013 | 1 | 2013 |
| Directed Evolution of an Feᴵᴵ-Dependent Halogenase for Asymmetric C (sp³)-H Chlorination S Duewel, L Schmermund, T Faber, K Harms, V Srinivasan, E Meggers, ... | | 2019 |
| Engineering the substrate scope of the Fe (II) dependent halogenase WelO15 S Hoebenreich, S Düwel, L Schmermund, H Müller, V Srinivasan | | 2017 |
Carlos G. Acevedo-RochaDTU BiosustainBestätigte E-Mail-Adresse bei biosustain.dtu.dk
