p53 dynamics control cell fate JE Purvis, KW Karhohs, C Mock, E Batchelor, A Loewer, G Lahav Science 336 (6087), 1440-1444, 2012 | 865 | 2012 |
Recurrent initiation: a mechanism for triggering p53 pulses in response to DNA damage E Batchelor, CS Mock, I Bhan, A Loewer, G Lahav Molecular cell 30 (3), 277-289, 2008 | 511 | 2008 |
Stimulus‐dependent dynamics of p53 in single cells E Batchelor, A Loewer, C Mock, G Lahav Molecular systems biology 7 (1), 488, 2011 | 393 | 2011 |
The ups and downs of p53: understanding protein dynamics in single cells E Batchelor, A Loewer, G Lahav Nature Reviews Cancer 9 (5), 371-377, 2009 | 307 | 2009 |
Robustness and the cycle of phosphorylation and dephosphorylation in a two-component regulatory system E Batchelor, M Goulian Proceedings of the National Academy of Sciences 100 (2), 691-696, 2003 | 292 | 2003 |
Basal dynamics of p53 reveal transcriptionally attenuated pulses in cycling cells A Loewer, E Batchelor, G Gaglia, G Lahav Cell 142 (1), 89-100, 2010 | 285 | 2010 |
The Escherichia coli CpxA-CpxR Envelope Stress Response System Regulates Expression of the Porins OmpF and OmpC E Batchelor, D Walthers, LJ Kenney, M Goulian Journal of bacteriology 187 (16), 5723-5731, 2005 | 227 | 2005 |
Myc regulates chromatin decompaction and nuclear architecture during B cell activation KR Kieffer-Kwon, K Nimura, SSP Rao, J Xu, S Jung, A Pekowska, M Dose, ... Molecular cell 67 (4), 566-578. e10, 2017 | 191 | 2017 |
Fourier analysis and systems identification of the p53 feedback loop N Geva-Zatorsky, E Dekel, E Batchelor, G Lahav, U Alon Proceedings of the National Academy of Sciences 107 (30), 13550-13555, 2010 | 107 | 2010 |
NFκB Promotes Ovarian Tumorigenesis via Classical Pathways That Support Proliferative Cancer Cells and Alternative Pathways That Support ALDH+ Cancer … CD House, E Jordan, L Hernandez, M Ozaki, JM James, M Kim, ... Cancer research 77 (24), 6927-6940, 2017 | 92 | 2017 |
A synthetic–natural hybrid oscillator in human cells JE Toettcher, C Mock, E Batchelor, A Loewer, G Lahav Proceedings of the National Academy of Sciences 107 (39), 17047-17052, 2010 | 86 | 2010 |
p53 pulses diversify target gene expression dynamics in an mRNA half-life-dependent manner and delineate co-regulated target gene subnetworks JR Porter, BE Fisher, E Batchelor Cell systems 2 (4), 272-282, 2016 | 83 | 2016 |
CRISPR/Cas9-mediated gene knockout is insensitive to target copy number but is dependent on guide RNA potency and Cas9/sgRNA threshold expression level G Yuen, FJ Khan, S Gao, JM Stommel, E Batchelor, X Wu, J Luo Nucleic acids research 45 (20), 12039-12053, 2017 | 80 | 2017 |
Continuous control in bacterial regulatory circuits E Batchelor, TJ Silhavy, M Goulian Journal of bacteriology 186 (22), 7618-7625, 2004 | 68 | 2004 |
Global inhibition with specific activation: how p53 and MYC redistribute the transcriptome in the DNA double-strand break response JR Porter, BE Fisher, L Baranello, JC Liu, DM Kambach, Z Nie, WS Koh, ... Molecular cell 67 (6), 1013-1025. e9, 2017 | 64 | 2017 |
Imaging OmpR localization in Escherichia coli E Batchelor, M Goulian Molecular microbiology 59 (6), 1767-1778, 2006 | 59 | 2006 |
Dissecting transcriptional amplification by MYC Z Nie, C Guo, SK Das, CC Chow, E Batchelor, SS Simons, D Levens Elife 9, e52483, 2020 | 52 | 2020 |
Disabled cell density sensing leads to dysregulated cholesterol synthesis in glioblastoma DM Kambach, AS Halim, AG Cauer, Q Sun, CA Tristan, O Celiku, ... Oncotarget 8 (9), 14860, 2017 | 45 | 2017 |
Far upstream element binding protein plays a crucial role in embryonic development, hematopoiesis, and stabilizing Myc expression levels W Zhou, YJ Chung, ERP Castellar, Y Zheng, HJ Chung, R Bandle, J Liu, ... The American journal of pathology 186 (3), 701-715, 2016 | 39 | 2016 |
p53 pulse modulation differentially regulates target gene promoters to regulate cell fate decisions MD Harton, WS Koh, AD Bunker, A Singh, E Batchelor Molecular Systems Biology 15 (9), e8685, 2019 | 33 | 2019 |