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Marc Siggel
Marc Siggel
Postdoctoral Fellow (EIPOD), EMBL Hamburg
Verified email at embl-hamburg.de
Title
Cited by
Cited by
Year
Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex
X Wu, M Siggel, S Ovchinnikov, W Mi, V Svetlov, E Nudler, M Liao, ...
Science 368 (6489), eaaz2449, 2020
1772020
AI-based structure prediction empowers integrative structural analysis of human nuclear pores
S Mosalaganti, A Obarska-Kosinska, M Siggel, R Taniguchi, B Turoňová, ...
Science 376 (6598), eabm9506, 2022
169*2022
Dynamic cluster formation determines viscosity and diffusion in dense protein solutions
S von Bülow, M Siggel, M Linke, G Hummer
Proceedings of the National Academy of Sciences 116 (20), 9843-9852, 2019
1392019
PyContact: rapid, customizable, and visual analysis of noncovalent interactions in MD simulations
M Scheurer, P Rodenkirch, M Siggel, RC Bernardi, K Schulten, ...
Biophysical journal 114 (3), 577-583, 2018
902018
Antimalarial inhibitors targeting serine hydroxymethyltransferase (SHMT) with in vivo efficacy and analysis of their binding mode based on X-ray cocrystal structures
G Schwertz, MC Witschel, M Rottmann, R Bonnert, U Leartsakulpanich, ...
Journal of medicinal chemistry 60 (12), 4840-4860, 2017
442017
Visualizing the disordered nuclear transport machinery in situ
M Yu, M Heidari, S Mikhaleva, PS Tan, S Mingu, H Ruan, ...
Nature 617 (7959), 162-169, 2023
40*2023
Membrane fusion and drug delivery with carbon nanotube porins
NT Ho, M Siggel, KV Camacho, RM Bhaskara, JM Hicks, YC Yao, ...
Proceedings of the National Academy of Sciences 118 (19), e2016974118, 2021
292021
Variable microtubule architecture in the malaria parasite
JL Ferreira, V Pražák, D Vasishtan, M Siggel, F Hentzschel, AM Binder, ...
Nature Communications 14 (1), 1216, 2023
22*2023
FAM134B-RHD protein clustering drives spontaneous budding of asymmetric membranes
M Siggel, RM Bhaskara, MK Moesser, I Dikic, G Hummer
The Journal of Physical Chemistry Letters 12 (7), 1926-1931, 2021
192021
MDBenchmark: A toolkit to optimize the performance of molecular dynamics simulations
M Gecht, M Siggel, M Linke, G Hummer, J Köfinger
The Journal of Chemical Physics 153 (14), 2020
182020
Phospholipid scramblases remodel the shape of asymmetric membranes
M Siggel, RM Bhaskara, G Hummer
The Journal of Physical Chemistry Letters 10 (20), 6351-6354, 2019
142019
Tracking of fluorescently labeled polymer particles reveals surface effects during shear-controlled aggregation
S Caimi, A Cingolani, B Jaquet, M Siggel, M Lattuada, M Morbidelli
Langmuir 33 (49), 14038-14044, 2017
112017
TriMem: A parallelized hybrid Monte Carlo software for efficient simulations of lipid membranes
M Siggel, S Kehl, K Reuter, J Köfinger, G Hummer
The journal of chemical physics 157 (17), 2022
72022
Sensing their plasma membrane curvature allows migrating cells to circumvent obstacles
E Sitarska, SD Almeida, MS Beckwith, J Stopp, J Czuchnowski, M Siggel, ...
Nature Communications 14 (1), 5644, 2023
62023
The distance between the plasma membrane and the actomyosin cortex acts as a nanogate to control cell surface mechanics
S Lembo, L Strauss, D Cheng, J Vermeil, M Siggel, M Toro-Nahuelpan, ...
bioRxiv, 2023.01. 31.526409, 2023
32023
PyTME (Python Template Matching Engine): A fast, flexible, and multi-purpose template matching library for cryogenic electron microscopy data
VJ Maurer, M Siggel, J Kosinski
SoftwareX 25, 101636, 2024
22024
What shapes template matching performance in cryogenic electron tomography in situ
VJ Maurer, M Siggel, J Kosinski
bioRxiv, 2023.09. 06.556487, 2023
2*2023
ColabSeg: An interactive tool for editing, processing, and visualizing membrane segmentations from cryo-ET data
M Siggel, RK Jensen, VJ Maurer, J Mahamid, J Kosinski
Journal of Structural Biology, 108067, 2024
12024
Nanotube-vesicle compositions and uses thereof
A Noy, NT HO, G Hummer, M Siggel
US Patent App. 17/121,578, 2021
12021
Integrative Structural Analysis of Human Nuclear Pore Complex
S Mosalaganti, A Obarska-Kosinska, M Siggel, R Taniguchi, B Turoňová, ...
Microscopy and Microanalysis 28 (S1), 1114-1114, 2022
2022
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