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Annette M Vogl
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Glutamatergic and dopaminergic neurons mediate anxiogenic and anxiolytic effects of CRHR1
D Refojo, M Schweizer, C Kuehne, S Ehrenberg, C Thoeringer, AM Vogl, ...
Science 333 (6051), 1903-1907, 2011
3462011
Conditional mouse mutants highlight mechanisms of corticotropin-releasing hormone effects on stress-coping behavior
A Lu, MA Steiner, N Whittle, AM Vogl, SM Walser, M Ableitner, D Refojo, ...
Molecular psychiatry 13 (11), 1028-1042, 2008
1612008
Chronic CRH depletion from GABAergic, long-range projection neurons in the extended amygdala reduces dopamine release and increases anxiety
N Dedic, C Kühne, M Jakovcevski, J Hartmann, AJ Genewsky, KS Gomes, ...
Nature neuroscience 21 (6), 803-807, 2018
1122018
MicroRNA-9 controls dendritic development by targeting REST
SA Giusti, AM Vogl, MM Brockmann, CA Vercelli, ML Rein, D Trümbach, ...
Elife 3, e02755, 2014
1102014
Urocortin 3 modulates social discrimination abilities via corticotropin-releasing hormone receptor type 2
JM Deussing, J Breu, C Kühne, M Kallnik, M Bunck, L Glasl, YC Yen, ...
Journal of Neuroscience 30 (27), 9103-9116, 2010
982010
Behavioral phenotyping of Nestin-Cre mice: implications for genetic mouse models of psychiatric disorders
SA Giusti, CA Vercelli, AM Vogl, AW Kolarz, NS Pino, JM Deussing, ...
Journal of psychiatric research 55, 87-95, 2014
952014
Neddylation inhibition impairs spine development, destabilizes synapses and deteriorates cognition
AM Vogl, MM Brockmann, SA Giusti, G Maccarrone, CA Vercelli, ...
Nature neuroscience 18 (2), 239-251, 2015
902015
Global site-specific neddylation profiling reveals that NEDDylated cofilin regulates actin dynamics
AM Vogl, L Phu, R Becerra, SA Giusti, E Verschueren, TB Hinkle, ...
Nature Structural & Molecular Biology 27 (2), 210-220, 2020
642020
Conditional CRH overexpressing mice: an animal model for stress-elicited pathologies and treatments that target the central CRH system
A Lu, MA Steiner, N Whittle, AM Vogl, SM Walser, M Ableitner, D Refojo, ...
Molecular psychiatry 13 (11), 989-989, 2008
192008
Immunology, Signal Transduction, and Behavior in Hypothalamic–Pituitary–Adrenal Axis‐related Genetic Mouse Models
S Silberstein, AM Vogl, JJ Bonfiglio, W Wurst, F Holsboer, E Arzt, ...
Annals of the New York Academy of Sciences 1153 (1), 120-130, 2009
182009
Amygdaloid pERK1/2 in corticotropin-releasing hormone overexpressing mice under basal and acute stress conditions
S Silberstein, AM Vogl, D Refojo, SA Senin, W Wurst, F Holsboer, ...
Neuroscience 159 (2), 610-617, 2009
132009
Vitamin D3 signalling in the brain enhances the function of phosphoprotein enriched in astrocytes – 15 kD (PEA‐15)
D Obradovic, C Zanca, A Vogl, D Trümbach, J Deussing, G Condorelli, ...
Journal of Cellular and Molecular Medicine 13 (9b), 3315-3328, 2009
72009
Bis‐ethynylphosphonamidates as an Modular Conjugation Platform to Generate Multi‐Functional Protein‐and Antibody‐Drug‐Conjugates
MA Kasper, L Lassak, AM Vogl, I Mai, J Helma, D Schumacher, ...
European Journal of Organic Chemistry 2022 (10), e202101389, 2022
62022
chumacher M, von Wolff G
D Refojo, M Schweizer, C Kuehne, S Ehrenberg, C Thoeringer, AM Vogl, ...
Avrabos C, Touma C, Engblom D, Schutz G, Nave KA, Eder M, Wotjak CT …, 2011
32011
Conditional overexpression of corticotropin-releasing hormone in mice, an animal model for understanding the development of corticotropin-releasing hormone-mediated brain pathology
JM Deussing, A Lu, MA Steiner, AM Vogl, F Holsboer, CT Wotjak, W Wurst
The International Journal of Neuropsychopharmacology 11, 117, 2008
22008
Tub-010, a novel antibody-drug-conjugate with reduced nonspecific toxicity profile based on tub-tag technology widens the therapeutic window for the treatment of CD30+ Malignancies
M Gerlach, S Schmitt, P Cyprys, MA Kasper, I Mai, MH Vermeer, ...
Blood 140 (Supplement 1), 9397-9398, 2022
12022
TUB-040, a novel Napi2b-targeting ADC built with ethynylphosphonamidate conjugation chemistry, demonstrates high and long-lasting anti-tumor efficacy via Topoisomerase-I …
S Schmitt, I Mai, P Machui, S Herterich, D Hauswald, P Ochtrop, P Cyprys, ...
Cancer Research 84 (6_Supplement), 2622-2622, 2024
2024
Enabling 5T4 for targeted cancer therapy: TUB-030, a novel ADC built with ethynylphosphonamidate conjugation chemistry, shows long-lasting anti-tumor activity via Topoisomerase …
S Schmitt, I Mai, P Machui, S Herterich, D Hauswald, P Ochtrop, P Cyprys, ...
Cancer Research 84 (6_Supplement), 2623-2623, 2024
2024
Design and Evaluation of Phosphonamidate-Linked Exatecan Constructs for Highly Loaded, Stable, and Efficacious Antibody–Drug Conjugates
S Schmitt, P Machui, I Mai, S Herterich, S Wunder, P Cyprys, M Gerlach, ...
Molecular Cancer Therapeutics 23 (2), 199-211, 2024
2024
Conjugates comprising a phosphorus (v) and a camptothecin moiety
M Kasper, P Machui, MAI Isabelle, V Annette, S Schmitt, D Schumacher, ...
US Patent App. 18/054,063, 2023
2023
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