| Long-term treatment of primary pulmonary hypertension with aerosolized iloprost, a prostacyclin analogue MM Hoeper, M Schwarze, S Ehlerding, A Adler-Schuermeyer, ... New England Journal of Medicine 342 (25), 1866-1870, 2000 | 760 | 2000 |
| Goal-oriented treatment and combination therapy for pulmonary arterial hypertension MM Hoeper, I Markevych, E Spiekerkoetter, T Welte, J Niedermeyer European Respiratory Journal 26 (5), 858-863, 2005 | 628 | 2005 |
| FK506 activates BMPR2, rescues endothelial dysfunction, and reverses pulmonary hypertension E Spiekerkoetter, X Tian, J Cai, RK Hopper, D Sudheendra, CG Li, ... The Journal of clinical investigation 123 (8), 3600-3613, 2013 | 454 | 2013 |
| Bosentan treatment in patients with primary pulmonary hypertension receiving nonparenteral prostanoids MM Hoeper, N Taha, A Bekjarova, R Gatzke, E Spiekerkoetter European Respiratory Journal 22 (2), 330-334, 2003 | 284 | 2003 |
| Hedgehog signaling restrains bladder cancer progression by eliciting stromal production of urothelial differentiation factors K Shin, A Lim, C Zhao, D Sahoo, Y Pan, E Spiekerkoetter, JC Liao, ... Cancer cell 26 (4), 521-533, 2014 | 207 | 2014 |
| Experience with inhaled iloprost and bosentan in portopulmonary hypertension MM Hoeper, HJ Seyfarth, G Hoeffken, H Wirtz, E Spiekerkoetter, MW Pletz, ... European Respiratory Journal 30 (6), 1096-1102, 2007 | 206 | 2007 |
| Interdependent serotonin transporter and receptor pathways regulate S100A4/Mts1, a gene associated with pulmonary vascular disease A Lawrie, E Spiekerkoetter, EC Martinez, N Ambartsumian, WJ Sheward, ... Circulation research 97 (3), 227-235, 2005 | 193 | 2005 |
| Reduced BMPR2 expression induces GM-CSF translation and macrophage recruitment in humans and mice to exacerbate pulmonary hypertension H Sawada, T Saito, NP Nickel, TP Alastalo, JP Glotzbach, R Chan, ... Journal of Experimental Medicine 211 (2), 263-280, 2014 | 146 | 2014 |
| Randomised placebo-controlled safety and tolerability trial of FK506 (tacrolimus) for pulmonary arterial hypertension E Spiekerkoetter, YK Sung, D Sudheendra, V Scott, P Del Rosario, M Bill, ... European Respiratory Journal 50 (3), 2017 | 142 | 2017 |
| Elafin reverses pulmonary hypertension via caveolin-1–dependent bone morphogenetic protein signaling NP Nickel, E Spiekerkoetter, M Gu, CG Li, H Li, M Kaschwich, I Diebold, ... American journal of respiratory and critical care medicine 191 (11), 1273-1286, 2015 | 140 | 2015 |
| Low-dose FK506 (tacrolimus) in end-stage pulmonary arterial hypertension E Spiekerkoetter, YK Sung, D Sudheendra, M Bill, MA Aldred, ... American journal of respiratory and critical care medicine 192 (2), 254-257, 2015 | 130 | 2015 |
| Increased fibulin-5 and elastin in S100A4/Mts1 mice with pulmonary hypertension SL Merklinger, RA Wagner, E Spiekerkoetter, A Hinek, RH Knutsen, ... Circulation research 97 (6), 596-604, 2005 | 111 | 2005 |
| S100A4 and Bone Morphogenetic Protein-2 Codependently Induce Vascular Smooth Muscle Cell Migration via Phospho–Extracellular Signal-Regulated Kinase and Chloride Intracellular … E Spiekerkoetter, C Guignabert, V de Jesus Perez, TP Alastalo, ... Circulation research 105 (7), 639-647, 2009 | 99 | 2009 |
| Neutrophil elastase is produced by pulmonary artery smooth muscle cells and is linked to neointimal lesions YM Kim, L Haghighat, E Spiekerkoetter, H Sawada, CM Alvira, L Wang, ... The American journal of pathology 179 (3), 1560-1572, 2011 | 95 | 2011 |
| RNA sequencing analysis detection of a novel pathway of endothelial dysfunction in pulmonary arterial hypertension CJ Rhodes, H Im, A Cao, JK Hennigs, L Wang, S Sa, PI Chen, NP Nickel, ... American journal of respiratory and critical care medicine 192 (3), 356-366, 2015 | 89 | 2015 |
| New and emerging therapies for pulmonary arterial hypertension E Spiekerkoetter, SM Kawut, VA de Jesus Perez Annual Review of Medicine 70, 45-59, 2019 | 82 | 2019 |
| Consequences of BMPR2 deficiency in the pulmonary vasculature and beyond: contributions to pulmonary arterial hypertension A Andruska, E Spiekerkoetter International journal of molecular sciences 19 (9), 2499, 2018 | 81 | 2018 |
| BMP promotes motility and represses growth of smooth muscle cells by activation of tandem Wnt pathways VA de Jesus Perez, Z Ali, TP Alastalo, F Ikeno, H Sawada, YJ Lai, T Kleisli, ... Journal of cell biology 192 (1), 171-188, 2011 | 80 | 2011 |
| Current clinical management of pulmonary arterial hypertension RT Zamanian, KT Kudelko, YK Sung, V de Jesus Perez, J Liu, ... Circulation research 115 (1), 131-147, 2014 | 69 | 2014 |
| Intravenous iloprost for treatment failure of aerosolised iloprost in pulmonary arterial hypertension MM Hoeper, E Spiekerkoetter, V Westerkamp, R Gatzke, H Fabel European Respiratory Journal 20 (2), 339-343, 2002 | 60 | 2002 |
