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Prof. Dr. med. Ralf Linker
Prof. Dr. med. Ralf Linker
Professor und Lehrstuhl für Neurologie, Universität Regensburg
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Zitiert von
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Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells
M Kleinewietfeld, A Manzel, J Titze, H Kvakan, N Yosef, RA Linker, ...
Nature 496 (7446), 518-522, 2013
14502013
Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway
RA Linker, DH Lee, S Ryan, AM van Dam, R Conrad, P Bista, W Zeng, ...
Brain 134 (3), 678-692, 2011
11972011
Salt-responsive gut commensal modulates TH17 axis and disease
N Wilck, MG Matus, SM Kearney, SW Olesen, K Forslund, ...
Nature 551 (7682), 585-589, 2017
10832017
Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 study
L Kappos, A Bar-Or, BAC Cree, RJ Fox, G Giovannoni, R Gold, ...
The Lancet 391 (10127), 1263-1273, 2018
9372018
Dietary fatty acids directly impact central nervous system autoimmunity via the small intestine
A Haghikia, S Jörg, A Duscha, J Berg, A Manzel, A Waschbisch, ...
Immunity 43 (4), 817-829, 2015
8222015
Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: a multicentre study of 175 patients
S Jarius, K Ruprecht, B Wildemann, T Kuempfel, M Ringelstein, C Geis, ...
Journal of neuroinflammation 9, 1-17, 2012
8112012
Role of “Western diet” in inflammatory autoimmune diseases
A Manzel, DN Muller, DA Hafler, SE Erdman, RA Linker, M Kleinewietfeld
Current allergy and asthma reports 14, 1-8, 2014
5422014
CNTF is a major protective factor in demyelinating CNS disease: a neurotrophic cytokine as modulator in neuroinflammation
RA Linker, M Mäurer, S Gaupp, R Martini, B Holtmann, R Giess, ...
Nature medicine 8 (6), 620-624, 2002
4752002
Propionic acid shapes the multiple sclerosis disease course by an immunomodulatory mechanism
A Duscha, B Gisevius, S Hirschberg, N Yissachar, GI Stangl, E Dawin, ...
Cell 180 (6), 1067-1080. e16, 2020
4022020
Neuromyelitis optica: evaluation of 871 attacks and 1,153 treatment courses
I Kleiter, A Gahlen, N Borisow, K Fischer, KD Wernecke, B Wegner, ...
Annals of neurology 79 (2), 206-216, 2016
3842016
Failure of natalizumab to prevent relapses in neuromyelitis optica
I Kleiter, K Hellwig, A Berthele, T Kümpfel, RA Linker, HP Hartung, F Paul, ...
Archives of neurology 69 (2), 239-245, 2012
3342012
Fumaric acid esters are effective in chronic experimental autoimmune encephalomyelitis and suppress macrophage infiltration
S Schilling, S Goelz, R Linker, F Luehder, R Gold
Clinical & Experimental Immunology 145 (1), 101-107, 2006
3272006
High salt reduces the activation of IL-4–and IL-13–stimulated macrophages
KJ Binger, M Gebhardt, M Heinig, C Rintisch, A Schroeder, W Neuhofer, ...
The Journal of clinical investigation 125 (11), 4223-4238, 2015
2762015
Functional role of brain-derived neurotrophic factor in neuroprotective autoimmunity: therapeutic implications in a model of multiple sclerosis
RA Linker, DH Lee, S Demir, S Wiese, N Kruse, I Siglienti, E Gerhardt, ...
Brain 133 (8), 2248-2263, 2010
2222010
Impacts of microbiome metabolites on immune regulation and autoimmunity
S Haase, A Haghikia, N Wilck, DN Müller, RA Linker
Immunology 154 (2), 230-238, 2018
2202018
Glatiramer acetate treatment normalizes deregulated microRNA expression in relapsing remitting multiple sclerosis
A Waschbisch, M Atiya, RA Linker, S Potapov, S Schwab, T Derfuss
PloS one 6 (9), e24604, 2011
2082011
Role of the renin-angiotensin system in autoimmune inflammation of the central nervous system
J Stegbauer, DH Lee, S Seubert, G Ellrichmann, A Manzel, H Kvakan, ...
Proceedings of the National Academy of Sciences 106 (35), 14942-14947, 2009
2042009
Apheresis therapies for NMOSD attacks: a retrospective study of 207 therapeutic interventions
I Kleiter, A Gahlen, N Borisow, K Fischer, KD Wernecke, K Hellwig, ...
Neurology: Neuroimmunology & Neuroinflammation 5 (6), e504, 2018
1922018
Efficacy of fumaric acid esters in the R6/2 and YAC128 models of Huntington's disease
G Ellrichmann, E Petrasch-Parwez, DH Lee, C Reick, L Arning, C Saft, ...
PloS one 6 (1), e16172, 2011
1912011
Function of neurotrophic factors beyond the nervous system: inflammation and autoimmune demyelination
R Linker, R Gold, F Luhder
Critical Reviews™ in Immunology 29 (1), 2009
1852009
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