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K. P. Connie Tam, Ph.D.
K. P. Connie Tam, Ph.D.
Cleveland Clinic Cole Eye Institute and Lerner Research Institute
Bestätigte E-Mail-Adresse bei ccf.org
Titel
Zitiert von
Zitiert von
Jahr
Cytokeratins mediate epithelial innate defense through their antimicrobial properties
C Tam, JJ Mun, DJ Evans, SMJ Fleiszig
The Journal of clinical investigation 122 (10), 3665-3677, 2012
1552012
Factors impacting corneal epithelial barrier function against Pseudomonas aeruginosa traversal
I Alarcon, C Tam, JJ Mun, J LeDue, DJ Evans, SMJ Fleiszig
Investigative ophthalmology & visual science 52 (3), 1368-1377, 2011
942011
Clearance of Pseudomonas aeruginosa from a Healthy Ocular Surface Involves Surfactant Protein D and Is Compromised by Bacterial Elastase in a Murine Null …
JJ Mun, C Tam, D Kowbel, S Hawgood, MJ Barnett, DJ Evans, ...
Infection and immunity 77 (6), 2392-2398, 2009
872009
Role of Defensins in Corneal Epithelial Barrier Function against Pseudomonas aeruginosa Traversal
DK Augustin, SR Heimer, C Tam, WY Li, JM Le Due, DJ Evans, ...
Infection and immunity 79 (2), 595-605, 2011
822011
The impact of inoculation parameters on the pathogenesis of contact lens–related infectious keratitis
C Tam, JJ Mun, DJ Evans, SMJ Fleiszig
Investigative ophthalmology & visual science 51 (6), 3100-3106, 2010
802010
Association between cytotoxic and invasive Pseudomonas aeruginosa and clinical outcomes in bacterial keratitis
DS Borkar, SMJ Fleiszig, C Leong, P Lalitha, M Srinivasan, AA Ghanekar, ...
JAMA ophthalmology 131 (2), 147-153, 2013
722013
MicroRNA-762 is upregulated in human corneal epithelial cells in response to tear fluid and Pseudomonas aeruginosa antigens and negatively regulates the expression of host …
J Mun, C Tam, G Chan, JH Kim, D Evans, S Fleiszig
PloS one 8 (2), e57850, 2013
522013
Adenylate cyclase activity of Pseudomonas aeruginosa ExoY can mediate bleb-niche formation in epithelial cells and contributes to virulence
V Hritonenko, JJ Mun, C Tam, NC Simon, JT Barbieri, DJ Evans, ...
Microbial pathogenesis 51 (5), 305-312, 2011
462011
Salmonella enterica serovar Dublin strains which are Vi antigen-positive use type IVB pili for bacterial self-association and human intestinal cell entry
C Morris, CKP Tam, TS Wallis, PW Jones, J Hackett
Microbial pathogenesis 35 (6), 279-284, 2003
412003
3D quantitative imaging of unprocessed live tissue reveals epithelial defense against bacterial adhesion and subsequent traversal requires MyD88
C Tam, J LeDue, JJ Mun, P Herzmark, EA Robey, DJ Evans, SMJ Fleiszig
PLoS One 6 (8), e24008, 2011
402011
Mutation of the phospholipase catalytic domain of the Pseudomonas aeruginosa cytotoxin ExoU abolishes colonization promoting activity and reduces corneal disease severity
C Tam, SE Lewis, WY Li, E Lee, DJ Evans, SMJ Fleiszig
Experimental eye research 85 (6), 799-805, 2007
392007
Modulation of epithelial immunity by mucosal fluid
JJ Mun, C Tam, DJ Evans, SMJ Fleiszig
Scientific reports 1 (1), 8, 2011
352011
Expression of surfactant protein D in human corneal epithelial cells is upregulated by Pseudomonas aeruginosa
M Ni, C Tam, A Verma, R Ramphal, S Hawgood, DJ Evans, SMJ Fleiszig
FEMS Immunology & Medical Microbiology 54 (2), 177-184, 2008
302008
Topical tacrolimus nanocapsules eye drops for therapeutic effect enhancement in both anterior and posterior ocular inflammation models
L Rebibo, C Tam, Y Sun, E Shoshani, A Badihi, T Nassar, S Benita
Journal of Controlled Release 333, 283-297, 2021
262021
Traversal of multilayered corneal epithelia by cytotoxic Pseudomonas aeruginosa requires the phospholipase domain of exoU
JC Ramirez, SMJ Fleiszig, AB Sullivan, C Tam, R Borazjani, DJ Evans
Investigative ophthalmology & visual science 53 (1), 448-453, 2012
262012
A novel murine model for contact lens wear reveals clandestine IL-1R dependent corneal parainflammation and susceptibility to microbial keratitis upon inoculation with …
MME Metruccio, SJ Wan, H Horneman, AR Kroken, AB Sullivan, ...
The ocular surface 17 (1), 119-133, 2019
252019
Keratin 6a reorganization for ubiquitin–proteasomal processing is a direct antimicrobial response
JKL Chan, D Yuen, PHM Too, Y Sun, B Willard, D Man, C Tam
Journal of Cell Biology 217 (2), 731-744, 2018
242018
Contributions of MyD88-dependent receptors and CD11c-positive cells to corneal epithelial barrier function against Pseudomonas aeruginosa
MME Metruccio, C Tam, DJ Evans, AL Xie, ME Stern, SMJ Fleiszig
Scientific reports 7 (1), 13829, 2017
232017
Membrane-active epithelial keratin 6A fragments (KAMPs) are unique human antimicrobial peptides with a non-αβ structure
JTY Lee, G Wang, YT Tam, C Tam
Frontiers in microbiology 7, 222508, 2016
202016
Salmonella enterica Serovar Paratyphi C Carries an Inactive Shufflon
CKP Tam, J Hackett, C Morris
Infection and immunity 72 (1), 22-28, 2004
162004
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