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Penka Nikolova
Penka Nikolova
Emeritus Associate Professor (Reader), King's College London
Bestätigte E-Mail-Adresse bei kcl.ac.uk
Titel
Zitiert von
Zitiert von
Jahr
Thermodynamic stability of wild-type and mutant p53 core domain
AN Bullock, J Henckel, BS DeDecker, CM Johnson, PV Nikolova, ...
Proceedings of the National Academy of Sciences 94 (26), 14338-14342, 1997
5231997
A peptide that binds and stabilizes p53 core domain: chaperone strategy for rescue of oncogenic mutants
A Friedler, LO Hansson, DB Veprintsev, SMV Freund, TM Rippin, ...
Proceedings of the National Academy of Sciences 99 (2), 937-942, 2002
3432002
Semirational design of active tumor suppressor p53 DNA binding domain with enhanced stability
PV Nikolova, J Henckel, DP Lane, AR Fersht
Proceedings of the National Academy of Sciences 95 (25), 14675-14680, 1998
3001998
Mechanism of rescue of common p53 cancer mutations by second-site suppressor mutations
PV Nikolova, KB Wong, B DeDecker, J Henckel, AR Fersht
The EMBO journal 19 (3), 370-378, 2000
2082000
Whole cell biocatalysis in nonconventional media
P Nikolova, OP Ward
Journal of industrial microbiology 12, 76-86, 1993
1211993
Molecular interactions of ASPP1 and ASPP2 with the p53 protein family and the apoptotic promoters PUMA and Bax
S Patel, R George, F Autore, F Fraternali, JE Ladbury, PV Nikolova
Nucleic acids research 36 (16), 5139-5151, 2008
742008
Production of L‐phenylacetyl carbinol by biotransformation: Product and by‐product formation and activities of the key enzymes in wild‐type and ADH isoenzyme mutants of …
P Nikolova, OP Ward
Biotechnology and bioengineering 38 (5), 493-498, 1991
581991
Insights into the Conformations of Three Structurally Diverse Proteins: Cytochrome c, p53, and MDM2, Provided by Variable-Temperature Ion Mobility Mass …
ER Dickinson, E Jurneczko, KJ Pacholarz, DJ Clarke, M Reeves, KL Ball, ...
Analytical chemistry 87 (6), 3231-3238, 2015
452015
Intrinsic disorder in proteins: a challenge for (un) structural biology met by ion mobility–mass spectrometry
E Jurneczko, F Cruickshank, M Porrini, P Nikolova, IDG Campuzano, ...
Biochemical Society Transactions 40 (5), 1021-1026, 2012
452012
Probing the conformational diversity of cancer‐associated mutations in p53 with ion‐mobility mass spectrometry
E Jurneczko, F Cruickshank, M Porrini, DJ Clarke, IDG Campuzano, ...
Angewandte Chemie 125 (16), 4466-4470, 2013
422013
Whole cell yeast biotransformations in two-phase systems: effect of solvent on product formation and cell structure
P Nikolova, OP Ward
Journal of industrial microbiology 10, 169-177, 1992
421992
Reductive biotransformation by wild type and mutant strains of Saccharomyces cerevisiae in aqueous‐organic solvent biphasic systems
P Nikolova, OP Ward
Biotechnology and bioengineering 39 (8), 870-876, 1992
391992
Mutants of the tumour suppressor p53 L1 loop as second-site suppressors for restoring DNA binding to oncogenic p53 mutations: structural and biochemical insights
A Merabet, H Houlleberghs, K Maclagan, E Akanho, TTT Bui, B Pagano, ...
Biochemical Journal 427 (2), 225-236, 2010
352010
Thermostability and irreversible activity loss of exoglucanase/xylanase Cex from Cellulomonas fimi
PV Nikolova, AL Creagh, SJB Duff, CA Haynes
Biochemistry 36 (6), 1381-1388, 1997
311997
The p73 DNA binding domain displays enhanced stability relative to its homologue, the tumor suppressor p53, and exhibits cooperative DNA binding
S Patel, TTT Bui, AF Drake, F Fraternali, PV Nikolova
Biochemistry 47 (10), 3235-3244, 2008
292008
A thermodynamic study of aqueous acetonitrile: excess chemical potentials, partial molar enthalpies, entropies and volumes, and fluctuations
PV Nikolova, SJB Duff, P Westh, CA Haynes, Y Kasahara, K Nishikawa, ...
Canadian Journal of Chemistry 78 (12), 1553-1560, 2000
282000
Consequences of point mutations in melanoma-associated antigen 4 (MAGE-A4) protein: Insights from structural and biophysical studies
Y Hagiwara, L Sieverling, F Hanif, J Anton, ER Dickinson, TTT Bui, ...
Scientific reports 6 (1), 25182, 2016
252016
Structure and stability insights into tumour suppressor p53 evolutionary related proteins
B Pagano, A Jama, P Martinez, E Akanho, TTT Bui, AF Drake, F Fraternali, ...
PLoS One 8 (10), e76014, 2013
252013
Utilising ion mobility-mass spectrometry to interrogate macromolecules: Factor H complement control protein modules 10–15 and 19–20 and the DNA-binding core domain of tumour …
PA Faull, HV Florance, CQ Schmidt, N Tomczyk, PN Barlow, TR Hupp, ...
International Journal of Mass Spectrometry 298 (1-3), 99-110, 2010
212010
Effect of support matrix on ratio of product to by-product formation in L-phenylacetyl carbinol synthesis
P Nikolova, OP Ward
Biotechnology letters 16, 7-10, 1994
191994
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