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Alix M.B. Lacoste
Alix M.B. Lacoste
Invitae, Harvard University, IBM Watson Health, BenevolentAI
Bestätigte E-Mail-Adresse bei invitae.com - Startseite
Titel
Zitiert von
Zitiert von
Jahr
Whole-brain activity mapping onto a zebrafish brain atlas
O Randlett, CL Wee, EA Naumann, O Nnaemeka, D Schoppik, ...
Nature methods 12 (11), 1039-1046, 2015
3452015
Artificial intelligence in neurodegenerative disease research: use of IBM Watson to identify additional RNA-binding proteins altered in amyotrophic lateral sclerosis
N Bakkar, T Kovalik, I Lorenzini, S Spangler, A Lacoste, K Sponaugle, ...
Acta neuropathologica 135 (2), 227-247, 2018
1112018
Applications of machine learning to diagnosis and treatment of neurodegenerative diseases
MA Myszczynska, PN Ojamies, A Lacoste, D Neil, A Saffari, R Mead, ...
Nature Reviews Neurology 16 (8), 440-456, 2020
1022020
A convergent and essential interneuron pathway for Mauthner-cell-mediated escapes
AMB Lacoste, D Schoppik, DN Robson, M Haesemeyer, R Portugues, ...
Current Biology 25 (11), 1526-1534, 2015
862015
Zebrafish oxytocin neurons drive nocifensive behavior via brainstem premotor targets
CL Wee, M Nikitchenko, WC Wang, SJ Luks-Morgan, E Song, JA Gagnon, ...
Nature neuroscience 22 (9), 1477-1492, 2019
362019
Repurposing drugs to treat l-DOPA-induced dyskinesia in Parkinson's disease
TH Johnston, AMB Lacoste, NP Visanji, AE Lang, SH Fox, JM Brotchie
Neuropharmacology 147, 11-27, 2019
262019
Interpretable graph convolutional neural networks for inference on noisy knowledge graphs
D Neil, J Briody, A Lacoste, A Sim, P Creed, A Saffari
arXiv preprint arXiv:1812.00279, 2018
262018
Preclinical validation of therapeutic targets predicted by tensor factorization on heterogeneous graphs
S Paliwal, A de Giorgio, D Neil, JB Michel, A Lacoste
Scientific reports 10 (1), 1-19, 2020
142020
Identifying drugs with disease‐modifying potential in Parkinson's disease using artificial intelligence and pharmacoepidemiology
LC Maclagan, NP Visanji, Y Cheng, M Tadrous, AMB Lacoste, LV Kalia, ...
Pharmacoepidemiology and Drug Safety 29 (8), 864-872, 2020
132020
Identification of pharmacodynamic biomarker hypotheses through literature analysis with IBM Watson
S Hatz, S Spangler, A Bender, M Studham, P Haselmayer, AMB Lacoste, ...
PloS one 14 (4), e0214619, 2019
82019
Small molecule inhibitors of α-synuclein oligomers identified by targeting early dopamine-mediated motor impairment in C. elegans
KS Chen, K Menezes, JB Rodgers, DM O’Hara, N Tran, K Fujisawa, ...
Molecular neurodegeneration 16 (1), 1-25, 2021
52021
Using artificial intelligence to identify anti‐hypertensives as possible disease modifying agents in Parkinson's disease
NP Visanji, P Madan, AMB Lacoste, I Buleje, Y Han, S Spangler, LV Kalia, ...
Pharmacoepidemiology and Drug Safety 30 (2), 201-209, 2021
52021
Expert-augmented computational drug repurposing identified baricitinib as a treatment for COVID-19
DP Smith, O Oechsle, MJ Rawling, E Savory, A Lacoste, PJ Richardson
Frontiers in pharmacology, 1699, 2021
52021
Classification of cardiovascular proteins involved in coronary atherosclerosis and heart failure using Watson’s cognitive computing technology
CT Ruff, A Lacoste, F Nordio, CL Fanola, MG Silverman, E Argentinis, ...
Circulation 136 (suppl_1), A16678-A16678, 2017
42017
Graph neutral networks with attention
P Creed, SIM Aaron, A Alamdari, J Briody, D Neil, A Lacoste
US Patent App. 17/041,625, 2021
12021
Rationalizing network predictions using similarity to known connections
A Lacoste, WS Spangler, F Wang
US Patent 10,607,074, 2020
12020
Using artificial intelligence and real-world data to identify drugs to repurpose for Parkinson's disease
SH Alford, NP Visanji, A Lacoste, P Madan, I Buleje, Y Han, C Marras
PHARMACOEPIDEMIOLOGY AND DRUG SAFETY 28, 131-131, 2019
12019
Data curation on predictive data modelling platform
S Saranathan, AB Fokoue-Nkoutche, A Lacoste
US Patent 11,243,988, 2022
2022
Machine learning for ranking candidate subjects based on a training set
AM Lacoste, WS Spangler
US Patent 11,182,692, 2021
2021
Extraction and normalization of mutant genes from unstructured text for cognitive search and analytics
RL Martin, AJJ Yepes, DM Iraola, A Lacoste, C Schieber
US Patent 11,170,031, 2021
2021
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