| Structural insights into the mechanism and inhibition of eukaryotic O‐GlcNAc hydrolysis FV Rao, HC Dorfmueller, F Villa, M Allwood, IM Eggleston, ... The EMBO journal 25 (7), 1569-1578, 2006 | 251 | 2006 |
| GlcNAcstatin: a picomolar, selective O-GlcNAcase inhibitor that modulates intracellular O-GlcNAcylation levels HC Dorfmueller, VS Borodkin, M Schimpl, SM Shepherd, NA Shpiro, ... Journal of the American Chemical Society 128 (51), 16484-16485, 2006 | 174 | 2006 |
| GlcNAcstatins are nanomolar inhibitors of human O-GlcNAcase inducing cellular hyper-O-GlcNAcylation HC Dorfmueller, VS Borodkin, M Schimpl, DMF van Aalten Biochemical Journal 420 (2), 221-227, 2009 | 99 | 2009 |
| Chemical Dissection of the Link between Streptozotocin, O-GlcNAc, and Pancreatic Cell Death S Pathak, HC Dorfmueller, VS Borodkin, DMF van Aalten Chemistry & biology 15 (8), 799-807, 2008 | 88 | 2008 |
| Substrate and product analogues as human O-GlcNAc transferase inhibitors HC Dorfmueller, VS Borodkin, DE Blair, S Pathak, I Navratilova, ... Amino acids 40, 781-792, 2011 | 87 | 2011 |
| Molecular mechanisms of O-GlcNAcylation R Hurtado-Guerrero, HC Dorfmueller, DMF van Aalten Current opinion in structural biology 18 (5), 551-557, 2008 | 80 | 2008 |
| Cell-Penetrant, Nanomolar O-GlcNAcase Inhibitors Selective against Lysosomal Hexosaminidases HC Dorfmueller, VS Borodkin, M Schimpl, X Zheng, R Kime, KD Read, ... Chemistry & biology 17 (11), 1250-1255, 2010 | 76 | 2010 |
| Bisubstrate UDP-peptide conjugates as human O-GlcNAc transferase inhibitors. ADM Borodkin VS, Schimpl M, Gundogdu M, Rafie K, Dorfmueller HC, Robinson DA Biochem J. 457 ((3)), 497-502, 2014 | 74 | 2014 |
| Structure of a bacterial putative acetyltransferase defines the fold of the human O-GlcNAcase C-terminal domain. ADM Rao FV, Schüttelkopf AW, Dorfmueller HC, Ferenbach AT, Navratilova I Open Biol 3 ((10)), 130021, 2013 | 71 | 2013 |
| A brief review on Group A Streptococcus pathogenesis and vaccine development SA Castro, HC Dorfmueller Royal Society open science 8 (3), 201991, 2021 | 55 | 2021 |
| A structural and biochemical model of processive chitin synthesis. ADM Dorfmueller HC, Ferenbach AT, Borodkin VS J Biol Chem 289 ((33)), 23020-8, 2014 | 52 | 2014 |
| Streptococcal dTDP‐L‐rhamnose biosynthesis enzymes: functional characterization and lead compound identification SL van der Beek, A Zorzoli, E Çanak, RN Chapman, K Lucas, BH Meyer, ... Molecular microbiology 111 (4), 951-964, 2019 | 50 | 2019 |
| GacA is essential for Group A Streptococcus and defines a new class of monomeric dTDP‐4‐dehydrorhamnose reductases (RmlD) SL van der Beek, Y Le Breton, AT Ferenbach, RN Chapman, ... Molecular microbiology 98 (5), 946-962, 2015 | 50 | 2015 |
| Scalar nanostructure of the Candida albicans cell wall; a molecular, cellular and ultrastructural analysis and interpretation MD Lenardon, P Sood, HC Dorfmueller, AJP Brown, NAR Gow The Cell Surface 6, 100047, 2020 | 46 | 2020 |
| Screening-based discovery of drug-like O-GlcNAcase inhibitor scaffolds HC Dorfmueller, DMF van Aalten FEBS letters 584 (4), 694-700, 2010 | 33 | 2010 |
| Group A, B, C, and G Streptococcus Lancefield antigen biosynthesis is initiated by a conserved α-d-GlcNAc-β-1, 4-l-rhamnosyltransferase A Zorzoli, BH Meyer, E Adair, VI Torgov, VV Veselovsky, LL Danilov, ... Journal of Biological Chemistry 294 (42), 15237-15256, 2019 | 32 | 2019 |
| Modification of cell wall polysaccharide guides cell division in Streptococcus mutans S Zamakhaeva, CT Chaton, JS Rush, S Ajay Castro, CW Kenner, ... Nature chemical biology 17 (8), 878-887, 2021 | 18 | 2021 |
| NDP-rhamnose biosynthesis and rhamnosyltransferases: building diverse glycoconjugates in nature BA Wagstaff, A Zorzoli, HC Dorfmueller Biochemical Journal 478 (4), 685-701, 2021 | 15 | 2021 |
| Discovery of an RmlC/D fusion protein in the microalga Prymnesium parvum and its implications for NDP-β-l-rhamnose biosynthesis in microalgae BA Wagstaff, M Rejzek, S Kuhaudomlarp, L Hill, I Mascia, SA Nepogodiev, ... Journal of Biological Chemistry 294 (23), 9172-9185, 2019 | 13 | 2019 |
| Structural and biochemical characterization of a trapped coenzyme A adduct of Caenorhabditis elegans glucosamine-6-phosphate N-acetyltransferase 1 HC Dorfmueller, W Fang, FV Rao, DE Blair, H Attrill, DMF van Aalten Acta Crystallographica Section D: Biological Crystallography 68 (8), 1019-1029, 2012 | 13 | 2012 |
Francesco RaoUniversity of DundeeBestätigte E-Mail-Adresse bei dundee.ac.uk
