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Jeff Klenc
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Synthesis of 4‐substituted 2‐(4‐methylpiperazino)pyrimidines and quinazoline analogs as serotonin 5‐HT2A receptor ligands
J Saczewski, A Paluchowska, J Klenc, E Raux, S Barnes, S Sullivan, ...
Journal of Heterocyclic Chemistry 46 (6), 1259-1265, 2009
1032009
Preclinical Evaluation of 99mTc(CO)3-aspartic-N-monoacetic acid, 99mTc(CO)3(ASMA), a new renal radiotracer with pharmacokinetic properties comparable to 131I-OIH.
M Lipowska, J Klenc, LG Marzilli, AT Taylor
Journal of Nuclear Medicine 53 (8), 1277-1283, 2012
20*2012
Al18F-NODA-butyric acid: biological evaluation of a new PET renal radiotracer
M Lipowska, J Klenc, D Shetty, JA Nye, H Shim, AT Taylor
Nuclear medicine and biology 41 (3), 248-253, 2014
192014
Synthesis and characterization of fac-Re(CO)3-aspartic-N-monoacetic acid: structural analog of a potential renal tracer, fac-99mTc(CO)3(ASMA).
J Klenc, M Lipowska, LG Marzilli, AT Taylor
European Jorunal of Inorganic Chemistry, 2012
192012
Re (CO) 3 ([18F] FEDA), a novel 18F PET renal tracer: radiosynthesis and preclinical evaluation
M Lipowska, N Jarkas, RJ Voll, JA Nye, J Klenc, MM Goodman, AT Taylor
Nuclear medicine and biology 58, 42-50, 2018
172018
fac-99mTc/Re-tricarbonyl complexes with tridentate aminocarboxyphosphonate ligands: Suitability of the phosphonate group in chelate ligand design of new imaging agents
M Lipowska, J Klenc, AT Taylor, LG Marzilli
Inorganica chimica acta 486, 529-537, 2019
142019
Monoanionic 99mTc-tricarbonyl-aminopolycarboxylate complexes with uncharged pendant groups: radiosynthesis and evaluation as potential renal tubular tracers
M Lipowska, J Klenc, N Jarkas, LG Marzilli, AT Taylor
Nuclear medicine and biology 47, 48-55, 2017
142017
Conjugate addition of nucleophiles to the vinyl function of 2-chloro-4-vinylpyrimidine derivatives
E Raux, J Klenc, A Blake, J Sączewski, L Strekowski
Molecules 15 (3), 1973-1984, 2010
92010
Structure and Properties of fac-[ReI (CO) 3 (NTA)] 2–(NTA3–= Trianion of Nitrilotriacetic Acid) and fac-[ReI (CO) 3 (L)] n–Analogues Useful for Assessing the Excellent Renal …
J Klenc, M Lipowska, PL Abhayawardhana, AT Taylor, LG Marzilli
Inorganic chemistry 54 (13), 6281-6290, 2015
72015
Synthesis and evaluation of 99mTc (CO) 3 (FEDA): a new dual-purpose 99mTc/18F renal imaging agent
J Klenc, A Taylor, M Lipowska
Journal of Nuclear Medicine 56 (supplement 3), 654-654, 2015
72015
Synthesis and Structure-Activity Relationship Analysis of 5-HT7 Receptor Antagonists: Piperazin-1-yl Substituted Unfused Heterobiaryls
L Strekowski, J Sączewski, EA Raux, NT Fernando, J Klenc, S Paranjpe, ...
Molecules 21 (4), 433, 2016
52016
Identification of lead compounds for 99mTc and 18F GPR91 radiotracers
J Klenc, M Lipowska, AT Taylor
Bioorganic & medicinal chemistry letters 25 (11), 2335-2339, 2015
52015
Initial Evaluation of 99mTc(CO)3(ASMA) as a Renal Tracer in Healthy Human Volunteers
M Lipowska, J Klenc, RD Folks, AT Taylor
Nuclear medicine and molecular imaging 48, 216-224, 2014
42014
The -NH-(C=)-Br functionality of heteroaromatic compounds as a synthon for fused dihydrooxazoles
MT Cegla, M Baran, A Czarny, M Zylewski, J Potaczek, J Klenc, ...
Journal of Heterocyclic Chemistry, 2011
32011
Metal tricarbonyl complexes comprising substituted iminodiactic acid ligands and uses as radioisotope tracers
J Klenc, M Lipowska, A Taylor
US Patent 10,633,404, 2020
12020
Radiosynthesis of Re (CO) 3 (18F-FEDA), a structural analog of 99mTc (CO) 3 (FEDA) and new PET tracer for renal imaging and renal function assessment
M Lipowska, N Jarkas, J Klenc, R Voll, M Goodman, A Taylor
Journal of Nuclear Medicine 57 (supplement 2), 1066-1066, 2016
12016
Evaluation of promising monoanionic 99mTc-tricarbonyl complexes with uncharged pendant groups as renal tubular tracers
M Lipowska, J Klenc, A Taylor
Journal of Nuclear Medicine 55 (supplement 1), 1206-1206, 2014
12014
Synthesis, characterization and in vivo biodistribution of 99mTc (CO) 3-N-carboxymethyl-aspartic acid as a potential renal imaging tracer
M Lipowska, J Klenc, E Malveaux, L Marzilli, A Taylor
Journal of Nuclear Medicine 52 (supplement 1), 345-345, 2011
12011
Synthesis, radiolabeling and characterization of novel rhenium (I) and technetium (I) tricarbonyl complexes with a tridentate, water-soluble phosphine-polycarboxylate ligand
M Lipowska, J Klenc, AT Taylor, LG Marzilli
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS 54, S19-S19, 2011
12011
Synthesis of piperazino-substituted benzo [b] furans as potential CNS agents
J Klenc, L Strekowski
Heterocyclic Communications 16 (4-6), 249-252, 2010
12010
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