| Crystal structure of Prp8 reveals active site cavity of the spliceosome WP Galej, C Oubridge, AJ Newman, K Nagai Nature 493 (7434), 638-643, 2013 | 252 | 2013 |
| The architecture of the spliceosomal U4/U6. U5 tri-snRNP THD Nguyen, WP Galej, X Bai, CG Savva, AJ Newman, SHW Scheres, ... Nature 523 (7558), 47-52, 2015 | 244 | 2015 |
| Cryo-EM structure of the spliceosome immediately after branching WP Galej, ME Wilkinson, SM Fica, C Oubridge, AJ Newman, K Nagai Nature 537 (7619), 197-201, 2016 | 242 | 2016 |
| Cryo-EM structure of the yeast U4/U6. U5 tri-snRNP at 3.7 Å resolution THD Nguyen, WP Galej, X Bai, C Oubridge, AJ Newman, SHW Scheres, ... Nature 530 (7590), 298-302, 2016 | 223 | 2016 |
| Structure of a spliceosome remodelled for exon ligation SM Fica, C Oubridge, WP Galej, ME Wilkinson, XC Bai, AJ Newman, ... Nature 542 (7641), 377-380, 2017 | 173 | 2017 |
| Inhibition of bacterial ubiquitin ligases by SidJ–calmodulin catalysed glutamylation S Bhogaraju, F Bonn, R Mukherjee, M Adams, MM Pfleiderer, WP Galej, ... Nature 572 (7769), 382-386, 2019 | 111 | 2019 |
| Postcatalytic spliceosome structure reveals mechanism of 3′–splice site selection ME Wilkinson, SM Fica, WP Galej, CM Norman, AJ Newman, K Nagai Science 358 (6368), 1283-1288, 2017 | 107 | 2017 |
| Structural basis of Brr2-Prp8 interactions and implications for U5 snRNP biogenesis and the spliceosome active site THD Nguyen, J Li, WP Galej, H Oshikane, AJ Newman, K Nagai Structure 21 (6), 910-919, 2013 | 93 | 2013 |
| Structural studies of the spliceosome: zooming into the heart of the machine WP Galej, THD Nguyen, AJ Newman, K Nagai Current opinion in structural biology 25, 57-66, 2014 | 66 | 2014 |
| CryoEM structures of two spliceosomal complexes: starter and dessert at the spliceosome feast THD Nguyen, WP Galej, SM Fica, PC Lin, AJ Newman, K Nagai Current opinion in structural biology 36, 48-57, 2016 | 64 | 2016 |
| Molecular mechanism and evolution of nuclear pre-mRNA and group II intron splicing: insights from cryo-electron microscopy structures WP Galej, N Toor, AJ Newman, K Nagai Chemical reviews 118 (8), 4156-4176, 2018 | 56 | 2018 |
| Structure of the catalytic core of the Integrator complex MM Pfleiderer, WP Galej Molecular cell 81 (6), 1246-1259. e8, 2021 | 47 | 2021 |
| Structural basis for conformational equilibrium of the catalytic spliceosome ME Wilkinson, SM Fica, WP Galej, K Nagai Molecular Cell 81 (7), 1439-1452. e9, 2021 | 34 | 2021 |
| Structural basis of branch site recognition by the human spliceosome J Tholen, M Razew, F Weis, WP Galej Science 375 (6576), 50-57, 2022 | 30 | 2022 |
| Structural studies of the spliceosome: past, present and future perspectives WP Galej Biochemical Society Transactions 46 (6), 1407-1422, 2018 | 27 | 2018 |
| Structural studies of the spliceosome: bridging the gaps J Tholen, WP Galej Current Opinion in Structural Biology 77, 102461, 2022 | 21 | 2022 |
| Emerging insights into the function and structure of the Integrator complex MM Pfleiderer, WP Galej Transcription 12 (5), 251-265, 2021 | 9 | 2021 |
| A combinatorial approach to uncover an additional Integrator subunit SR Offley, MM Pfleiderer, A Zucco, A Fraudeau, SA Welsh, M Razew, ... Cell reports 42 (3), 2023 | 8 | 2023 |
| PIM1 controls GBP1 activity to limit self-damage and to guard against pathogen infection D Fisch, MM Pfleiderer, E Anastasakou, GM Mackie, F Wendt, X Liu, ... Science 382 (6666), eadg2253, 2023 | 6 | 2023 |
| Characterization of the SF3B1–SUGP1 interface reveals how numerous cancer mutations cause mRNA missplicing J Zhang, J Xie, J Huang, X Liu, R Xu, J Tholen, WP Galej, L Tong, ... Genes & Development 37 (21-24), 968-983, 2023 | 3 | 2023 |
Sebastian M. FicaThe University of OxfordBestätigte E-Mail-Adresse bei bioch.ox.ac.uk
