| Lactate metabolism in human lung tumors B Faubert, KY Li, L Cai, CT Hensley, J Kim, LG Zacharias, C Yang, QN Do, ... Cell 171 (2), 358-371. e9, 2017 | 1063 | 2017 |
| A roadmap for interpreting 13C metabolite labeling patterns from cells JM Buescher, MR Antoniewicz, LG Boros, SC Burgess, H Brunengraber, ... Current opinion in biotechnology 34, 189-201, 2015 | 608 | 2015 |
| Molecular mechanisms and the role of saturated fatty acids in the progression of non-alcoholic fatty liver disease AK Leamy, RA Egnatchik, JD Young Progress in lipid research 52 (1), 165-174, 2013 | 491 | 2013 |
| INCA: a computational platform for isotopically non-stationary metabolic flux analysis JD Young Bioinformatics 30 (9), 1333-1335, 2014 | 400 | 2014 |
| Mapping photoautotrophic metabolism with isotopically nonstationary 13C flux analysis JD Young, AA Shastri, G Stephanopoulos, JA Morgan Metabolic engineering 13 (6), 656-665, 2011 | 394 | 2011 |
| An elementary metabolite unit (EMU) based method of isotopically nonstationary flux analysis JD Young, JL Walther, MR Antoniewicz, H Yoo, G Stephanopoulos Biotechnology and bioengineering 99 (3), 686-699, 2008 | 308 | 2008 |
| xCT (SLC7A11)-mediated metabolic reprogramming promotes non-small cell lung cancer progression X Ji, J Qian, SMJ Rahman, PJ Siska, Y Zou, BK Harris, MD Hoeksema, ... Oncogene 37 (36), 5007-5019, 2018 | 254 | 2018 |
| Peak antibody production is associated with increased oxidative metabolism in an industrially relevant fed‐batch CHO cell culture N Templeton, J Dean, P Reddy, JD Young Biotechnology and bioengineering 110 (7), 2013-2024, 2013 | 251 | 2013 |
| Isotopically nonstationary 13C flux analysis of changes in Arabidopsis thaliana leaf metabolism due to high light acclimation F Ma, LJ Jazmin, JD Young, DK Allen Proceedings of the National Academy of Sciences 111 (47), 16967-16972, 2014 | 240 | 2014 |
| ER calcium release promotes mitochondrial dysfunction and hepatic cell lipotoxicity in response to palmitate overload RA Egnatchik, AK Leamy, DA Jacobson, M Shiota, JD Young Molecular metabolism 3 (5), 544-553, 2014 | 180 | 2014 |
| Palmitate-induced activation of mitochondrial metabolism promotes oxidative stress and apoptosis in H4IIEC3 rat hepatocytes RA Egnatchik, AK Leamy, Y Noguchi, M Shiota, JD Young Metabolism 63 (2), 283-295, 2014 | 159 | 2014 |
| Metabolic flux rewiring in mammalian cell cultures JD Young Current opinion in biotechnology 24 (6), 1108-1115, 2013 | 152 | 2013 |
| Enhanced synthesis of saturated phospholipids is associated with ER stress and lipotoxicity in palmitate treated hepatic cells [S] AK Leamy, RA Egnatchik, M Shiota, PT Ivanova, DS Myers, HA Brown, ... Journal of lipid research 55 (7), 1478-1488, 2014 | 129 | 2014 |
| Carbon and nitrogen provisions alter the metabolic flux in developing soybean embryos DK Allen, JD Young Plant Physiology 161 (3), 1458-1475, 2013 | 110 | 2013 |
| Oncogenic KRAS and BRAF drive metabolic reprogramming in colorectal cancer JE Hutton, X Wang, LJ Zimmerman, RJC Slebos, IA Trenary, JD Young, ... Molecular & cellular proteomics 15 (9), 2924-2938, 2016 | 108 | 2016 |
| Isotopically nonstationary 13C flux analysis of Myc-induced metabolic reprogramming in B-cells TA Murphy, CV Dang, JD Young Metabolic engineering 15, 206-217, 2013 | 106 | 2013 |
| Integrating cybernetic modeling with pathway analysis provides a dynamic, systems‐level description of metabolic control JD Young, KL Henne, JA Morgan, AE Konopka, D Ramkrishna Biotechnology and bioengineering 100 (3), 542-559, 2008 | 89 | 2008 |
| Isotopically nonstationary 13C flux analysis of cyanobacterial isobutyraldehyde production LJ Jazmin, Y Xu, YE Cheah, AO Adebiyi, CH Johnson, JD Young Metabolic engineering 42, 9-18, 2017 | 87 | 2017 |
| Effect of anaplerotic fluxes and amino acid availability on hepatic lipoapoptosis Y Noguchi, JD Young, JO Aleman, ME Hansen, JK Kelleher, ... Journal of Biological Chemistry 284 (48), 33425-33436, 2009 | 85 | 2009 |
| The TLR4 agonist monophosphoryl lipid A drives broad resistance to infection via dynamic reprogramming of macrophage metabolism BA Fensterheim, JD Young, L Luan, RR Kleinbard, CL Stothers, NK Patil, ... The Journal of Immunology 200 (11), 3777-3789, 2018 | 76 | 2018 |
