Structures of active conformations of Gi-alpha1 and the mechanism of GTP hydrolysis DE Coleman, AM Berghuis, E Lee, ME Linder, AG Gilman, SR Sprangt Science 265, 1405, 1994 | 1128 | 1994 |
Structure of the first C2 domain of synaptotagmin I: a novel Ca2+/phospholipid-binding fold RB Sutton, BA Davletov, AM Berghuis, TC Sudhof, SR Sprang Cell 80 (6), 929-938, 1995 | 921 | 1995 |
IRF8 mutations and human dendritic-cell immunodeficiency S Hambleton, S Salem, J Bustamante, V Bigley, S Boisson-Dupuis, ... New England Journal of Medicine 365 (2), 127-138, 2011 | 655 | 2011 |
Oxidation state-dependent conformational changes in cytochrome c AM Berghuis, GD Brayer Journal of molecular biology 223 (4), 959-976, 1992 | 474 | 1992 |
Tertiary and quaternary structural changes in Giα1 induced by GTP hydrolysis MB Mixon, E Lee, DE Coleman, AM Berghuis, AG Gilman, SR Sprang Science 270 (5238), 954-960, 1995 | 401 | 1995 |
Structure of an enzyme required for aminoglycoside antibiotic resistance reveals homology to eukaryotic protein kinases WC Hon, GA McKay, PR Thompson, RM Sweet, DSC Yang, GD Wright, ... Cell 89 (6), 887-895, 1997 | 294 | 1997 |
Lactose binding to heat-labile enterotoxin revealed by X-ray crystallography TK Sixma, SME Pronk, KH Kalk, BAM van Zanten, AM Berghuis, WGJ Hol Nature 355 (6360), 561-564, 1992 | 251 | 1992 |
Aminoglycoside antibiotics: structures, functions, and resistance GD Wright, AM Berghuis, S Mobashery Resolving the antibiotic paradox: progress in understanding drug resistance …, 1998 | 215 | 1998 |
Substrate promiscuity of an aminoglycoside antibiotic resistance enzyme via target mimicry DH Fong, AM Berghuis The EMBO journal, 2002 | 212 | 2002 |
Crystal structures of cyclohexanone monooxygenase reveal complex domain movements and a sliding cofactor IA Mirza, BJ Yachnin, S Wang, S Grosse, H Bergeron, A Imura, H Iwaki, ... Journal of the American Chemical Society 131 (25), 8848-8854, 2009 | 209 | 2009 |
Crystal structure of an aminoglycoside 6′-N-acetyltransferase: defining the GCN5-related N-acetyltransferase superfamily fold LE Wybenga-Groot, K Draker, GD Wright, AM Berghuis Structure 7 (5), 497-507, 1999 | 176 | 1999 |
Germline and somatic FGFR1 abnormalities in dysembryoplastic neuroepithelial tumors B Rivera, T Gayden, J Carrot-Zhang, J Nadaf, T Boshari, D Faury, ... Acta neuropathologica 131, 847-863, 2016 | 169 | 2016 |
A recurrent PDGFRB mutation causes familial infantile myofibromatosis YH Cheung, T Gayden, PM Campeau, CA LeDuc, D Russo, VH Nguyen, ... The American Journal of Human Genetics 92 (6), 996-1000, 2013 | 157 | 2013 |
A single bifunctional UDP-GlcNAc/Glc 4-epimerase supports the synthesis of three cell surface glycoconjugates in Campylobacter jejuni S Bernatchez, CM Szymanski, N Ishiyama, J Li, HC Jarrell, PC Lau, ... Journal of Biological Chemistry 280 (6), 4792-4802, 2005 | 157 | 2005 |
The Role of a Conserved Internal Water Molecule and Its Associated Hydrogen Bond Network in Cytochrfome c AM Berghuis, JG Guillemette, G McLendon, F Sherman, M Smith, ... Journal of molecular biology 236 (3), 786-799, 1994 | 134 | 1994 |
Structural Analyses of Nucleotide Binding to an Aminoglycoside Phosphotransferase, DL Burk, WC Hon, AKW Leung, AM Berghuis Biochemistry 40 (30), 8756-8764, 2001 | 128 | 2001 |
Structural basis for ubiquitin-mediated dimerization and activation of the ubiquitin protein ligase Cbl-b P Peschard, G Kozlov, T Lin, IA Mirza, AM Berghuis, S Lipkowitz, M Park, ... Molecular cell 27 (3), 474-485, 2007 | 126 | 2007 |
Synthesis and Structure−Activity Relationships of Truncated Bisubstrate Inhibitors of Aminoglycoside 6‘-N-Acetyltransferases F Gao, X Yan, T Shakya, OM Baettig, S Ait-Mohand-Brunet, AM Berghuis, ... Journal of medicinal chemistry 49 (17), 5273-5281, 2006 | 115 | 2006 |
Histone H3. 3G34-mutant interneuron progenitors co-opt PDGFRA for gliomagenesis CCL Chen, S Deshmukh, S Jessa, D Hadjadj, V Lisi, AF Andrade, D Faury, ... Cell 183 (6), 1617-1633. e22, 2020 | 113 | 2020 |
Effect of the Asn52→ Ile mutation on the redox potential of yeast cytochrome c: theory and experiment R Langen, GD Brayer, AM Berghuis, G McLendon, F Sherman, A Warshel Journal of molecular biology 224 (3), 589-600, 1992 | 112 | 1992 |