Michael Schwarz
Michael Schwarz
Professor of Toxicology University of Tuebingen
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Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating …
P Godoy, NJ Hewitt, U Albrecht, ME Andersen, N Ansari, S Bhattacharya, ...
Archives of toxicology 87, 1315-1530, 2013
A strategy for structuring and reporting a read-across prediction of toxicity
TW Schultz, P Amcoff, E Berggren, F Gautier, M Klaric, DJ Knight, ...
Regulatory Toxicology and Pharmacology 72 (3), 586-601, 2015
Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010
S Adler, D Basketter, S Creton, O Pelkonen, J Van Benthem, V Zuang, ...
Archives of toxicology 85, 367-485, 2011
Prediction and validation of cell alignment along microvessels as order principle to restore tissue architecture in liver regeneration
S Hoehme, M Brulport, A Bauer, E Bedawy, W Schormann, M Hermes, ...
Proceedings of the National Academy of Sciences 107 (23), 10371-10376, 2010
High incidence of spontaneous and chemically induced liver tumors in mice deficient for connexin32
A Temme, A Buchmann, HD Gabriel, E Nelles, M Schwarz, K Willecke
Current Biology 7 (9), 713-716, 1997
Adverse outcome pathways: opportunities, limitations and open questions
M Leist, A Ghallab, R Graepel, R Marchan, R Hassan, SH Bennekou, ...
Archives of Toxicology 91, 3477-3505, 2017
Diethylnitrosamine (DEN)-induced carcinogenic liver injury in mice
R Tolba, T Kraus, C Liedtke, M Schwarz, R Weiskirchen
Laboratory animals 49 (1_suppl), 59-69, 2015
A constitutively active dioxin/aryl hydrocarbon receptor promotes hepatocarcinogenesis in mice
O Moennikes, S Loeppen, A Buchmann, P Andersson, C Ittrich, ...
Cancer research 64 (14), 4707-4710, 2004
Differential gene expression in periportal and perivenous mouse hepatocytes
A Braeuning, C Ittrich, C Köhle, S Hailfinger, M Bonin, A Buchmann, ...
The FEBS journal 273 (22), 5051-5061, 2006
A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing
D Basketter, H Clewell, I Kimber, A Rossi, B Blaauboer, R Burrier, ...
Carcinogen-specific Mutational Pattern in the p53 Gene in Ultraviolet B Radiation-induced Squamous Cell Carcinomas of Mouse Skin
S Kress, C Sutter, PT Strickland, H Mukhtar, J Schweizer, M Schwarz
Cancer research 52 (22), 6400-6403, 1992
Inhibition of apoptosis during 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin-mediated tumour promotion in rat liver
S Stinchcombe, A Buchmann, KW Bock, M Schwarz
Carcinogenesis 16 (6), 1271-1275, 1995
Mutational activation of the c-Ha-ras gene in liver tumors of different rodent strains: correlation with susceptibility to hepatocarcinogenesis.
A Buchmann, R Bauer-Hofmann, J Mahr, NR Drinkwater, A Luz, ...
Proceedings of the National Academy of Sciences 88 (3), 911-915, 1991
Selective pressure during tumor promotion by phenobarbital leads to clonal outgrowth of β-catenin-mutated mouse liver tumors
H Aydinlik, TD Nguyen, O Moennikes, A Buchmann, M Schwarz
Oncogene 20 (53), 7812-7816, 2001
Consensus report on the future of animal-free systemic toxicity testing
M Leist, N Hasiwa, C Rovida, M Daneshian, D Basketter, I Kimber, ...
Zonal gene expression in murine liver: lessons from tumors
S Hailfinger, M Jaworski, A Braeuning, A Buchmann, M Schwarz
Hepatology 43 (3), 407-414, 2006
A Review of the Implementation of the Embryonic Stem Cell Test (EST) The report and recommendations of an ECVAM/ReProTect Workshop
P Marx-Stoelting, E Adriaens, HJ Ahr, S Bremer, B Garthoff, HP Gelbke, ...
Alternatives to Laboratory Animals 37 (3), 313-328, 2009
T‐cell factor 4 and β‐catenin chromatin occupancies pattern zonal liver metabolism in mice
A Gougelet, C Torre, P Veber, C Sartor, L Bachelot, PD Denechaud, ...
Hepatology 59 (6), 2344-2357, 2014
Regulation and expression of four cytochrome P-450 isoenzymes, NADPH-cytochrome P-450 reductase, the glutathione transferases B and C and microsomal epoxide hydrolase in …
A Buchmann, W Kuhlmann, M Schwarz, W Kunz, CR Wolf, E Moll, ...
Carcinogenesis 6 (4), 513-521, 1985
Aryl hydrocarbon receptor inhibition downregulates the TGF-β/Smad pathway in human glioblastoma cells
D Gramatzki, G Pantazis, J Schittenhelm, G Tabatabai, C Köhle, W Wick, ...
Oncogene 28 (28), 2593-2605, 2009
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