| The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis J Li, T McQuade, AB Siemer, J Napetschnig, K Moriwaki, YS Hsiao, ... Cell 150 (2), 339-350, 2012 | 1203 | 2012 |
| Widespread and functional RNA circularization in localized prostate cancer S Chen, V Huang, X Xu, J Livingstone, F Soares, J Jeon, Y Zeng, JT Hua, ... Cell 176 (4), 831-843. e22, 2019 | 343 | 2019 |
| Cas12aVDet: a CRISPR/Cas12a-based platform for rapid and visual nucleic acid detection B Wang, R Wang, D Wang, J Wu, J Li, J Wang, H Liu, Y Wang Analytical chemistry 91 (19), 12156-12161, 2019 | 283 | 2019 |
| The structure of the necrosome RIPK1-RIPK3 core, a human hetero-amyloid signaling complex M Mompeán, W Li, J Li, S Laage, AB Siemer, G Bozkurt, H Wu, ... Cell 173 (5), 1244-1253. e10, 2018 | 270 | 2018 |
| Structure insight of GSDMD reveals the basis of GSDMD autoinhibition in cell pyroptosis S Kuang, J Zheng, H Yang, S Li, S Duan, Y Shen, C Ji, J Gan, XW Xu, J Li Proceedings of the National Academy of Sciences 114 (40), 10642-10647, 2017 | 208 | 2017 |
| Crystal structure of an RNA-cleaving DNAzyme H Liu, X Yu, Y Chen, J Zhang, B Wu, L Zheng, P Haruehanroengra, ... Nature Communications 8, 2006, 2017 | 150 | 2017 |
| Structural basis of signal transduction in the TNF receptor superfamily J Li, Q Yin, H Wu Advances in immunology 119, 135-153, 2013 | 142 | 2013 |
| Deacetylation of serine hydroxymethyl-transferase 2 by SIRT3 promotes colorectal carcinogenesis Z Wei, J Song, G Wang, X Cui, J Zheng, Y Tang, X Chen, J Li, L Cui, ... Nature communications 9 (1), 4468, 2018 | 130 | 2018 |
| Structural Biology of Innate Immunity Q Yin, TM Fu, J Li, H Wu Annual Review of Immunology 33, 393-416, 2015 | 119 | 2015 |
| Structural insights into the assembly of large oligomeric signalosomes in the Toll-like receptor–interleukin-1 receptor superfamily R Ferrao, J Li, E Bergamin, H Wu Science signaling 5 (226), re3-re3, 2012 | 85 | 2012 |
| A novel DNA structure containing AgI‐mediated G: G and C: C Base Pairs H Liu, F Shen, P Haruehanroengra, Q Yao, Y Cheng, Y Chen, C Yang, ... Angewandte Chemie, 2017 | 80* | 2017 |
| Peptidoglycan-sensing receptors trigger the formation of functional amyloids of the adaptor protein Imd to initiate Drosophila NF-κB signaling A Kleino, NF Ramia, G Bozkurt, Y Shen, H Nailwal, J Huang, ... Immunity 47 (4), 635-647. e6, 2017 | 77 | 2017 |
| Acetylation promotes TyrRS nuclear translocation to prevent oxidative damage X Cao, C Li, S Xiao, Y Tang, J Huang, S Zhao, X Li, J Li, R Zhang, W Yu Proceedings of the National Academy of Sciences 114 (4), 687-692, 2017 | 70 | 2017 |
| Identification of miPEP133 as a novel tumor-suppressor microprotein encoded by miR-34a pri-miRNA M Kang, B Tang, J Li, Z Zhou, K Liu, R Wang, Z Jiang, F Bi, D Patrick, ... Molecular cancer 19, 1-14, 2020 | 55 | 2020 |
| Mapping the broad structural and mechanical properties of amyloid fibrils G Lamour, R Nassar, PHW Chan, G Bozkurt, J Li, JM Bui, CK Yip, T Mayor, ... Biophysical Journal 112 (4), 584-594, 2017 | 53 | 2017 |
| Flexibility and stabilization of HgII-mediated C:T and T:T base pairs in DNA duplex H Liu, C Cai, P Haruehanroengra, Q Yao, Y Chen, C Yang, Q Luo, B Wu, ... Nucleic acids research 45 (5), 2910-2918, 2017 | 48 | 2017 |
| Metabolic intermediate acetyl phosphate modulates bacterial virulence via acetylation J Ren, Y Sang, R Qin, Y Su, Z Cui, Z Mang, H Li, S Lu, J Zhang, S Cheng, ... Emerging microbes & infections 8 (1), 55-69, 2019 | 45 | 2019 |
| Structural basis of cell apoptosis and necrosis in TNFR signaling J Huang, S Yu, C Ji, J Li Apoptosis 20, 210-215, 2015 | 45 | 2015 |
| Structural insights of a hormone sensitive lipase homologue Est22 J Huang, YY Huo, R Ji, S Kuang, C Ji, XW Xu, J Li Scientific Reports 6 (1), 28550, 2016 | 44 | 2016 |
| TRIM21 regulates pyroptotic cell death by promoting Gasdermin D oligomerization W Gao, Y Li, X Liu, S Wang, P Mei, Z Chen, K Liu, S Li, XW Xu, J Gan, ... Cell Death & Differentiation 29 (2), 439-450, 2022 | 43 | 2022 |
Hao WuAsa and Patricia Springer Professor, Boston Children's Hospital and Harvard Medical SchoolVerified email at crystal.harvard.edu
