Receptor for advanced glycation end products (RAGE) regulates sepsis but not the adaptive immune response B Liliensiek, MA Weigand, A Bierhaus, W Nicklas, M Kasper, S Hofer, ... The Journal of clinical investigation 113 (11), 1641-1650, 2004 | 646 | 2004 |
Spontaneous relapsing-remitting EAE in the SJL/J mouse: MOG-reactive transgenic T cells recruit endogenous MOG-specific B cells B Pöllinger, G Krishnamoorthy, K Berer, H Lassmann, MR Bösl, R Dunn, ... Journal of Experimental Medicine 206 (6), 1303-1316, 2009 | 370 | 2009 |
Dendritic cells ameliorate autoimmunity in the CNS by controlling the homeostasis of PD-1 receptor+ regulatory T cells N Yogev, F Frommer, D Lukas, K Kautz-Neu, K Karram, D Ielo, ... Immunity 37 (2), 264-275, 2012 | 242 | 2012 |
Mouse models for multiple sclerosis: historical facts and future implications AL Croxford, FC Kurschus, A Waisman Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1812 (2), 177-183, 2011 | 235 | 2011 |
Myelin-specific T cells also recognize neuronal autoantigen in a transgenic mouse model of multiple sclerosis G Krishnamoorthy, A Saxena, LT Mars, HS Domingues, R Mentele, ... Nature medicine 15 (6), 626-632, 2009 | 197 | 2009 |
Genetic proof for the transient nature of the Th17 phenotype FC Kurschus, AL Croxford, A P. Heinen, S Wörtge, D Ielo, A Waisman European journal of immunology 40 (12), 3336-3346, 2010 | 192 | 2010 |
An alternative pathway of imiquimod-induced psoriasis-like skin inflammation in the absence of interleukin-17 receptor a signaling K El Malki, SH Karbach, J Huppert, M Zayoud, S Reißig, R Schüler, ... Journal of Investigative Dermatology 133 (2), 441-451, 2013 | 177 | 2013 |
Imiquimod-induced psoriasis in mice depends on the IL-17 signaling of keratinocytes S Moos, AN Mohebiany, A Waisman, FC Kurschus Journal of Investigative Dermatology 139 (5), 1110-1117, 2019 | 149 | 2019 |
Inflammatory demyelination induces glia alterations and ganglion cell loss in the retina of an experimental autoimmune encephalomyelitis model L Horstmann, H Schmid, AP Heinen, FC Kurschus, HB Dick, SC Joachim Journal of neuroinflammation 10, 1-12, 2013 | 144 | 2013 |
Natural killer cell–derived human granzyme H induces an alternative, caspase-independent cell-death program E Fellows, S Gil-Parrado, DE Jenne, FC Kurschus Blood, The Journal of the American Society of Hematology 110 (2), 544-552, 2007 | 135 | 2007 |
IL-6 regulates neutrophil microabscess formation in IL-17A-driven psoriasiform lesions AL Croxford, S Karbach, FC Kurschus, S Wörtge, A Nikolaev, N Yogev, ... Journal of Investigative Dermatology 134 (3), 728-735, 2014 | 122 | 2014 |
Killing of target cells by redirected granzyme B in the absence of perforin FC Kurschus, M Kleinschmidt, E Fellows, K Dornmair, R Rudolph, H Lilie, ... FEBS letters 562 (1-3), 87-92, 2004 | 106 | 2004 |
T cell mediated pathogenesis in EAE: molecular mechanisms F Kurschus Biomedical journal 38 (3), 2015 | 92 | 2015 |
Delivery and therapeutic potential of human granzyme B FC Kurschus, DE Jenne Immunological reviews 235 (1), 159-171, 2010 | 91 | 2010 |
IL-17+ CD8+ T cell suppression by dimethyl fumarate associates with clinical response in multiple sclerosis C Lückel, F Picard, H Raifer, L Campos Carrascosa, A Guralnik, Y Zhang, ... Nature communications 10 (1), 5722, 2019 | 90 | 2019 |
Lugdunin amplifies innate immune responses in the skin in synergy with host-and microbiota-derived factors K Bitschar, B Sauer, J Focken, H Dehmer, S Moos, M Konnerth, ... Nature communications 10 (1), 2730, 2019 | 89 | 2019 |
EBI2 is highly expressed in multiple sclerosis lesions and promotes early CNS migration of encephalitogenic CD4 T cells F Wanke, S Moos, AL Croxford, AP Heinen, S Gräf, B Kalt, D Tischner, ... Cell reports 18 (5), 1270-1284, 2017 | 86 | 2017 |
Dietary tryptophan links encephalogenicity of autoreactive T cells with gut microbial ecology JK Sonner, M Keil, M Falk-Paulsen, N Mishra, A Rehman, M Kramer, ... Nature communications 10 (1), 4877, 2019 | 79 | 2019 |
Granzyme B delivery via perforin is restricted by size, but not by heparan sulfate-dependent endocytosis FC Kurschus, E Fellows, E Stegmann, DE Jenne Proceedings of the National Academy of Sciences 105 (37), 13799-13804, 2008 | 72 | 2008 |
Membrane receptors are not required to deliver granzyme B during killer cell attack FC Kurschus, R Bruno, E Fellows, CS Falk, DE Jenne Blood 105 (5), 2049-2058, 2005 | 72 | 2005 |