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Christopher C Kloss
Christopher C Kloss
Verified email at mail.med.upenn.edu
Title
Cited by
Cited by
Year
Combinatorial antigen recognition with balanced signaling promotes selective tumor eradication by engineered T cells
CC Kloss, M Condomines, M Cartellieri, M Bachmann, M Sadelain
Nature biotechnology, 2012
9642012
Structural design of engineered costimulation determines tumor rejection kinetics and persistence of CAR T cells
Z Zhao, M Condomines, SJC van der Stegen, F Perna, CC Kloss, ...
Cancer cell 28 (4), 415-428, 2015
7882015
Dominant Negative TGFβ Receptor Enhances PSMA Targeted Human CAR T Cell Proliferation and Augments Tumor Eradication in Prostate Cancer
CC Kloss, J Lee, A Zhang, F Chen, JJ Melenhorst, SF Lacey, MV Maus, ...
Molecular Therapy, 2018
492*2018
Generation of tumor-targeted human T lymphocytes from induced pluripotent stem cells for cancer therapy
M Themeli, CC Kloss, G Ciriello, VD Fedorov, F Perna, M Gonen, ...
Nature biotechnology, 2013
4922013
Rational development and characterization of humanized anti–EGFR variant III chimeric antigen receptor T cells for glioblastoma
LA Johnson, J Scholler, T Ohkuri, A Kosaka, PR Patel, SE McGettigan, ...
Science translational medicine 7 (275), 275ra22-275ra22, 2015
4902015
CD19 CAR-Targeted T Cells Induce Long-Term Remission and B Cell Aplasia in an Immunocompetent Mouse Model of B Cell Acute Lymphoblastic Leukemia
ML Davila, CC Kloss, G Gunset, M Sadelain
PloS one 8 (4), e61338, 2013
2332013
Human ESC-derived hemogenic endothelial cells undergo distinct waves of endothelial to hematopoietic transition
S Rafii, CC Kloss, JM Butler, M Ginsberg, E Gars, R Lis, Q Zhan, ...
Blood 121 (5), 770-780, 2013
1242013
Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration
T Wertheimer, E Velardi, J Tsai, K Cooper, S Xiao, CC Kloss, KJ Ottmüller, ...
Science immunology 3 (19), 2018
1192018
Driving cars to the clinic for solid tumors
M Castellarin, K Watanabe, CH June, CC Kloss, AD Posey
Gene therapy 25 (3), 165-175, 2018
852018
Activation of the vascular niche supports leukemic progression and resistance to chemotherapy
MG Poulos, EJ Gars, MC Gutkin, CC Kloss, M Ginsberg, JM Scandura, ...
Experimental hematology 42 (11), 976-986. e3, 2014
642014
A large-scale study of differential gene expression in monocyte-derived macrophages infected with several strains of Mycobacterium avium subspecies paratuberculosis
E Kabara, CC Kloss, M Wilson, RJ Tempelman, S Sreevatsan, ...
Briefings in Functional Genomics 9 (3), 220-237, 2010
632010
Chronic activation of endothelial MAPK disrupts hematopoiesis via NFKB dependent inflammatory stress reversible by SCGF
P Ramalingam, MG Poulos, E Lazzari, MC Gutkin, D Lopez, CC Kloss, ...
Nature communications 11 (1), 1-20, 2020
542020
Novel Approaches to Enhance the Specificity and Safety of Engineered T Cells
VD Fedorov, M Sadelain, CC Kloss
The Cancer Journal 20 (2), 160-165, 2014
512014
Double or nothing on cancer immunotherapy
K Hanada, NP Restifo
Nature biotechnology 31 (1), 33-34, 2013
222013
Lentiviral Transduction and Clonal Selection of hESCs with Endothelial‐Specific Transgenic Reporters
D James, Q Zhan, C Kloss, N Zaninovic, Z Rosenwaks, S Rafii
Current Protocols in Stem Cell Biology, 1F. 12.1-1F. 12.14, 2011
112011
Combinatorial antigen recognition with balanced signaling promotes selective tumor eradication by engineered T cells
CK CHRISTOPHER, M CONDOMINES, M CARTELLIERI, M BACHMANN, ...
NATURE BIOTECHNOLOGY 31 (1), 2012-12, 2012
102012
Production of BMP4 By Endothelial Cells Is Crucial for Endogenous Thymic Regeneration
T Wertheimer, E Velardi, C Brede, S Xiao, CC Kloss, A Beilhack, ...
Blood 126 (23), 637, 2015
22015
CD19-Targeted Donor T Cells Exert Potent Graft Versus Lymphoma Activity and Attenuated Gvhd
A Ghosh, ML Davila, LF Young, C Kloss, G Gunset, OM Smith, ML West, ...
BLOOD 120 (21), 2012
22012
Validation of a humanized anti-EGFR variant III chimeric antigen receptor for a Phase I trial of CART-EGFRvIII in glioblastoma
J Brogdon, A Loew, P Thekkat, N Idamakanti, B Engels, R Singh, T Ezell, ...
Science Translational Medicine, 2015
12015
4-1BBL costimulation enables CD4 T cells expressing a CD28/zeta chimeric antigen receptor to eliminate aggressive leukemia.(P4338)
M Condomines, Z Zhao, X Wang, C Kloss, M Davila, M Sadelain
The Journal of Immunology 190, 177.2, 2013
12013
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