| Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1α M Lagouge, C Argmann, Z Gerhart-Hines, H Meziane, C Lerin, F Daussin, ... Cell 127 (6), 1109-1122, 2006 | 4744 | 2006 |
| AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity C Cantó, Z Gerhart-Hines, JN Feige, M Lagouge, L Noriega, JC Milne, ... Nature 458 (7241), 1056-1060, 2009 | 3402 | 2009 |
| Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle C Cantó, LQ Jiang, AS Deshmukh, C Mataki, A Coste, M Lagouge, ... Cell metabolism 11 (3), 213-219, 2010 | 1039 | 2010 |
| Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation JN Feige, M Lagouge, C Canto, A Strehle, SM Houten, JC Milne, ... Cell metabolism 8 (5), 347-358, 2008 | 876 | 2008 |
| Sirtuins: The ‘magnificent seven’, function, metabolism and longevity N Dali‐Youcef, M Lagouge, S Froelich, C Koehl, K Schoonjans, J Auwerx Annals of medicine 39 (5), 335-345, 2007 | 529 | 2007 |
| The role of mitochondrial DNA mutations and free radicals in disease and ageing M Lagouge, NG Larsson Journal of internal medicine 273 (6), 529-543, 2013 | 364 | 2013 |
| Germline mitochondrial DNA mutations aggravate ageing and can impair brain development JM Ross, JB Stewart, E Hagström, S Brené, A Mourier, G Coppotelli, ... Nature 501 (7467), 412-415, 2013 | 291 | 2013 |
| Mitofusin 2 is required to maintain mitochondrial coenzyme Q levels A Mourier, E Motori, T Brandt, M Lagouge, I Atanassov, A Galinier, ... Journal of Cell Biology 208 (4), 429-442, 2015 | 228 | 2015 |
| The genetic ablation of SRC-3 protects against obesity and improves insulin sensitivity by reducing the acetylation of PGC-1α A Coste, JF Louet, M Lagouge, C Lerin, MC Antal, H Meziane, ... Proceedings of the National Academy of Sciences 105 (44), 17187-17192, 2008 | 226 | 2008 |
| Endoplasmic reticulum proteostasis in hepatic steatosis A Baiceanu, P Mesdom, M Lagouge, F Foufelle Nature Reviews Endocrinology 12 (12), 710-722, 2016 | 187 | 2016 |
| SIRT1 mRNA expression may be associated with energy expenditure and insulin sensitivity J Rutanen, N Yaluri, S Modi, J Pihlajamäki, M Vänttinen, P Itkonen, ... Diabetes 59 (4), 829-835, 2010 | 129 | 2010 |
| MTERF3 regulates mitochondrial ribosome biogenesis in invertebrates and mammals A Wredenberg, M Lagouge, A Bratic, MD Metodiev, H Spåhr, A Mourier, ... PLoS genetics 9 (1), e1003178, 2013 | 124 | 2013 |
| SLIRP regulates the rate of mitochondrial protein synthesis and protects LRPPRC from degradation M Lagouge, A Mourier, HJ Lee, H Spåhr, T Wai, C Kukat, E Silva Ramos, ... PLoS genetics 11 (8), e1005423, 2015 | 104 | 2015 |
| Methods and related compositions for treating or preventing obesity, insulin resistance disorders, and mitochondrial-associated disorders M Milburn, J Milne, J Auwerx, C Argmann, M Lagouge, M Dipp US Patent App. 11/374,295, 2007 | 103 | 2007 |
| Inhibition of receptor-interacting protein kinase 1 improves experimental non-alcoholic fatty liver disease A Majdi, L Aoudjehane, V Ratziu, T Islam, MB Afonso, F Conti, T Mestiri, ... Journal of hepatology 72 (4), 627-635, 2020 | 93 | 2020 |
| Human neural stem cell intracerebral grafts show spontaneous early neuronal differentiation after several weeks A Tennstaedt, M Aswendt, J Adamczak, U Collienne, M Selt, G Schneider, ... Biomaterials 44, 143-154, 2015 | 49 | 2015 |
| SIRT1/PGC-1 S Rasouri, M Lagouge, J Auwerx médecine/sciences 23, 840-4, 2007 | 42 | 2007 |
| Dietary manipulation of mouse metabolism JN Feige, M Lagouge, J Auwerx Current Protocols in Molecular Biology 84 (1), 29B. 5.1-29B. 5.12, 2008 | 21 | 2008 |
| A ROBUST, FAST, AND REPRODUCIBLE METHOD FOR ISOLATING HEPATIC STELLATE CELLS FROM C57/BL6 MICE. A Baiceanu, P Mesdom, I Hainault, C Ionescu, M Lagouge, F Foufelle Farmacia 66 (1), 2018 | 2 | 2018 |
| Methods and related compositions for treating or preventing obesity, insulin resistance disorders, and mitochondrial-associated disorders C Argmann, J Auwerx, M Dipp, M Lagouge, M Milburn, J Milne AU Patent App. 2,006,269,459 A, 2013 | 1 | 2013 |
Pere PuigserverProfessor of Cell and Cancer Biology, Harvard Medical SchoolVerified email at dfci.harvard.edu
