| Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents A Brai, R Fazi, C Tintori, C Zamperini, F Bugli, M Sanguinetti, E Stigliano, ... Proceedings of the National Academy of Sciences 113 (19), 5388-5393, 2016 | 116 | 2016 |
| Toward the discovery of novel anti‐HIV drugs. Second‐generation inhibitors of the cellular ATPase DDX3 with improved anti‐HIV activity: Synthesis, structure–activity … G Maga, F Falchi, M Radi, L Botta, G Casaluce, M Bernardini, H Irannejad, ... ChemMedChem 6 (8), 1371-1389, 2011 | 106 | 2011 |
| Discovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: towards the next generation HIV-1 inhibitors M Radi, F Falchi, A Garbelli, A Samuele, V Bernardo, S Paolucci, ... Bioorganic & medicinal chemistry letters 22 (5), 2094-2098, 2012 | 102 | 2012 |
| Pharmacophore modeling and molecular docking led to the discovery of inhibitors of human immunodeficiency virus-1 replication targeting the human cellular aspartic acid … G Maga, F Falchi, A Garbelli, A Belfiore, M Witvrouw, F Manetti, M Botta Journal of medicinal chemistry 51 (21), 6635-6638, 2008 | 100 | 2008 |
| A motif unique to the human DEAD-box protein DDX3 is important for nucleic acid binding, ATP hydrolysis, RNA/DNA unwinding and HIV-1 replication A Garbelli, S Beermann, G Di Cicco, U Dietrich, G Maga PloS one 6 (5), e19810, 2011 | 91 | 2011 |
| Homology model-based virtual screening for the identification of human helicase DDX3 inhibitors R Fazi, C Tintori, A Brai, L Botta, M Selvaraj, A Garbelli, G Maga, M Botta Journal of chemical information and modeling 55 (11), 2443-2454, 2015 | 85 | 2015 |
| The A rabidopsis STRESS RESPONSE SUPPRESSOR DEAD‐box RNA helicases are nucleolar‐and chromocenter‐localized proteins that undergo stress‐mediated relocalization and are … A Khan, A Garbelli, S Grossi, A Florentin, G Batelli, T Acuna, G Zolla, ... The Plant Journal 79 (1), 28-43, 2014 | 74 | 2014 |
| Targeting the human DEAD-box polypeptide 3 (DDX3) RNA helicase as a novel strategy to inhibit viral replication A Garbelli, M Radi, F Falchi, S Beermann, S Zanoli, F Manetti, U Dietrich, ... Current medicinal chemistry 18 (20), 3015-3027, 2011 | 67 | 2011 |
| DDX3X helicase inhibitors as a new strategy to fight the West Nile virus infection A Brai, F Martelli, V Riva, A Garbelli, R Fazi, C Zamperini, A Pollutri, ... Journal of medicinal chemistry 62 (5), 2333-2347, 2019 | 59 | 2019 |
| Synthesis and antiviral activity of novel 1, 3, 4-thiadiazole inhibitors of DDX3X A Brai, S Ronzini, V Riva, L Botta, C Zamperini, M Borgini, CI Trivisani, ... Molecules 24 (21), 3988, 2019 | 39 | 2019 |
| DDX3X inhibitors, an effective way to overcome HIV-1 resistance targeting host proteins A Brai, V Riva, F Saladini, C Zamperini, CI Trivisani, A Garbelli, C Pennisi, ... European Journal of Medicinal Chemistry 200, 112319, 2020 | 32 | 2020 |
| Mutational analysis of the HIV-1 auxiliary protein Vif identifies independent domains important for the physical and functional interaction with HIV-1 reverse transcriptase A Kataropoulou, C Bovolenta, A Belfiore, S Trabatti, A Garbelli, ... Nucleic acids research 37 (11), 3660-3669, 2009 | 28 | 2009 |
| Mutational analysis of the HIV-1 auxiliary protein Vif identifies independent domains important for the physical and functional interaction with HIV-1 reverse transcriptase A Kataropoulou, C Bovolenta, A Belfiore, S Trabatti, A Garbelli, ... Nucleic acids research 37 (11), 3660-3669, 2009 | 28 | 2009 |
| How to win the HIV-1 drug resistance hurdle race: running faster or jumping higher? A Garbelli, V Riva, E Crespan, G Maga Biochemical Journal 474 (10), 1559-1577, 2017 | 27 | 2017 |
| Exploring the implication of DDX3X in DENV infection: discovery of the first-in-class DDX3X fluorescent inhibitor A Brai, A Boccuto, M Monti, S Marchi, I Vicenti, F Saladini, CI Trivisani, ... ACS Medicinal Chemistry Letters 11 (5), 956-962, 2020 | 20 | 2020 |
| The PDZ-ligand and Src-homology type 3 domains of epidemic avian influenza virus NS1 protein modulate human Src kinase activity during viral infection L Bavagnoli, WG Dundon, A Garbelli, B Zecchin, A Milani, G Parakkal, ... PLoS One 6 (11), e27789, 2011 | 18 | 2011 |
| Exploiting the nucleotide substrate specificity of repair DNA polymerases to develop novel anticancer agents E Crespan, A Garbelli, A Amoroso, G Maga Molecules 16 (9), 7994-8019, 2011 | 16 | 2011 |
| Targeting cellular cofactors in HIV therapy R Dürr, O Keppler, F Christ, E Crespan, A Garbelli, G Maga, U Dietrich Therapy of Viral Infections, 183-222, 2015 | 13 | 2015 |
| Novel alternative ribonucleotide excision repair pathways in human cells by DDX3X and specialized DNA polymerases V Riva, A Garbelli, F Casiraghi, F Arena, CI Trivisani, A Gagliardi, L Bini, ... Nucleic Acids Research 48 (20), 11551-11565, 2020 | 9 | 2020 |
| Unique domain for a unique target: selective inhibitors of host cell DDX3X to fight emerging viruses V Riva, A Garbelli, A Brai, F Casiraghi, R Fazi, CI Trivisani, A Boccuto, ... Journal of Medicinal Chemistry 63 (17), 9876-9887, 2020 | 9 | 2020 |
Giovanni MagaIGM CNRVerified email at igm.cnr.it
