| Gene regulatory network inference: data integration in dynamic models - a review M Hecker, S Lambeck, S Toepfer, E Van Someren, R Guthke Biosystems 96 (1), 86-103, 2009 | 966 | 2009 |
| Molecular discrimination of responders and nonresponders to anti-TNFalpha therapy in rheumatoid arthritis by etanercept D Koczan, S Drynda, M Hecker, A Drynda, R Guthke, J Kekow, ... Arthritis research & therapy 10, 1-10, 2008 | 170 | 2008 |
| Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation TFM Andlauer, D Buck, G Antony, A Bayas, L Bechmann, A Berthele, ... Science advances 2 (6), e1501678, 2016 | 147 | 2016 |
| MicroRNA expression changes during interferon-beta treatment in the peripheral blood of multiple sclerosis patients M Hecker, M Thamilarasan, D Koczan, I Schröder, K Flechtner, ... International journal of molecular sciences 14 (8), 16087-16110, 2013 | 147 | 2013 |
| MicroRNAs in multiple sclerosis and experimental autoimmune encephalomyelitis M Thamilarasan, D Koczan, M Hecker, B Paap, UK Zettl Autoimmunity reviews 11 (3), 174-179, 2012 | 131 | 2012 |
| Fluorescent-increase kinetics of different fluorescent reporters used for qPCR depend on monitoring chemistry, targeted sequence, type of DNA input and PCR efficiency JM Ruijter, P Lorenz, JM Tuomi, M Hecker, MJB van den Hoff Microchimica Acta 181, 1689-1696, 2014 | 84 | 2014 |
| Molecular biomarkers in cerebrospinal fluid of multiple sclerosis patients B Fitzner, M Hecker, UK Zettl Autoimmunity reviews 14 (10), 903-913, 2015 | 81 | 2015 |
| High-density peptide microarray analysis of IgG autoantibody reactivities in serum and cerebrospinal fluid of multiple sclerosis patients M Hecker, B Fitzner, M Wendt, P Lorenz, K Flechtner, F Steinbeck, ... Molecular & cellular proteomics 15 (4), 1360-1380, 2016 | 75 | 2016 |
| Immunogenicity and predictors of response to a single dose trivalent seasonal influenza vaccine in multiple sclerosis patients receiving disease‐modifying therapies C Metze, A Winkelmann, M Loebermann, M Hecker, B Schweiger, ... CNS neuroscience & therapeutics 25 (2), 245-254, 2019 | 73 | 2019 |
| Analysis of microRNA and gene expression profiles in multiple sclerosis: integrating interaction data to uncover regulatory mechanisms S Freiesleben, M Hecker, UK Zettl, G Fuellen, L Taher Scientific reports 6 (1), 34512, 2016 | 72 | 2016 |
| Elevated type I interferon-like activity in a subset of multiple sclerosis patients: molecular basis and clinical relevance A Hundeshagen, M Hecker, BK Paap, C Angerstein, O Kandulski, ... Journal of Neuroinflammation 9 (1), 1-13, 2012 | 70 | 2012 |
| Integration of MicroRNA databases to study MicroRNAs associated with multiple sclerosis C Angerstein, M Hecker, BK Paap, D Koczan, M Thamilarasan, ... Molecular neurobiology 45, 520-535, 2012 | 60 | 2012 |
| Computational analysis of high-density peptide microarray data with application from systemic sclerosis to multiple sclerosis M Hecker, P Lorenz, F Steinbeck, L Hong, G Riemekasten, Y Li, UK Zettl, ... Autoimmunity reviews 11 (3), 180-190, 2012 | 59 | 2012 |
| Long-term genome-wide blood RNA expression profiles yield novel molecular response candidates for IFN-β-1b treatment in relapsing remitting MS RH Goertsches, M Hecker, D Koczan, P Serrano-Fernandez, S Moeller, ... Pharmacogenomics 11 (2), 147-161, 2010 | 56 | 2010 |
| Dysregulation of inflammasome priming and activation by MicroRNAs in human immune-mediated diseases N Boxberger, M Hecker, UK Zettl The Journal of Immunology 202 (8), 2177-2187, 2019 | 55 | 2019 |
| Multiple sclerosis: modulation of toll-like receptor (TLR) expression by interferon-β includes upregulation of TLR7 in plasmacytoid dendritic cells K Derkow, JMJ Bauer, M Hecker, BK Paap, M Thamilarasan, D Koczan, ... PLoS One 8 (8), e70626, 2013 | 55 | 2013 |
| Interferon-beta therapy in multiple sclerosis: the short-term and long-term effects on the patients’ individual gene expression in peripheral blood M Hecker, C Hartmann, O Kandulski, BK Paap, D Koczan, HJ Thiesen, ... Molecular neurobiology 48, 737-756, 2013 | 52 | 2013 |
| Interferon β-1a and β-1b for patients with multiple sclerosis: updates to current knowledge UK Zettl, M Hecker, O Aktas, T Wagner, PS Rommer Expert review of clinical immunology 14 (2), 137-153, 2018 | 51 | 2018 |
| Integrative modeling of transcriptional regulation in response to antirheumatic therapy M Hecker, RH Goertsches, R Engelmann, HJ Thiesen, R Guthke BMC bioinformatics 10, 1-18, 2009 | 51 | 2009 |
| Frequencies of polymorphisms in cytokines, neurotransmitters and adrenergic receptors in patients with complex regional pain syndrome type I after distal radial fracture P Herlyn, B Müller-Hilke, M Wendt, M Hecker, T Mittlmeier, G Gradl The Clinical journal of pain 26 (3), 175-181, 2010 | 49 | 2010 |
Dirk KoczanUniversitätsmedizin RostockBestätigte E-Mail-Adresse bei med.uni-rostock.de
