Selection of personalized patient therapy through the use of knowledge-based computational models that identify tumor-driving signal transduction pathways W Verhaegh, H van Ooijen, MA Inda, P Hatzis, R Versteeg, M Smid, ... Cancer research 74 (11), 2936-2945, 2014 | 109 | 2014 |
Assessment of functional phosphatidylinositol 3-kinase pathway activity in cancer tissue using forkhead box-O target gene expression in a knowledge-based computational model H Van Ooijen, M Hornsveld, C Dam-de Veen, R Velter, M Dou, ... The American journal of pathology 188 (9), 1956-1972, 2018 | 56 | 2018 |
Enabling precision medicine by unravelling disease pathophysiology: quantifying signal transduction pathway activity across cell and tissue types A Van De Stolpe, L Holtzer, H van Ooijen, MA Inda, W Verhaegh Scientific reports 9 (1), 1603, 2019 | 53 | 2019 |
ER and PI3K pathway activity in primary ER positive breast cancer is associated with progression-free survival of metastatic patients under first-line tamoxifen A M. Sieuwerts, M A. Inda, M Smid, H van Ooijen, A van de Stolpe, ... Cancers 12 (4), 802, 2020 | 22 | 2020 |
A molecular test for quantifying functional Notch signaling pathway activity in human cancer K Canté-Barrett, L Holtzer, H van Ooijen, R Hagelaar, V Cordo’, ... Cancers 12 (11), 3142, 2020 | 16 | 2020 |
Abstract P5-11-06: does hormone expression by IHC predict ER pathway activity? An analysis in a metastatic breast cancer patient cohort SR Yang, A Van De Stolpe, A Van Brussel, H Van Ooijen, A Galimzianova, ... Cancer Research 79 (4_Supplement), P5-11-06-P5-11-06, 2019 | 4 | 2019 |
Method of visualizing a bridge therapy process HJ Van Ooijen, R Van Den Ham, B Bakker US Patent 9,788,798, 2017 | 4 | 2017 |
Prognosis within different breast cancer subtypes using functional activity of signaling pathways H Van Ooijen, MA Inda, R Hoffmann, P van de Wiel, A van de Stolpe, ... Cancer Research 75 (15_Supplement), 5291-5291, 2015 | 3 | 2015 |
Does Hormone Expression by IHC predict ER Pathway Activity? An Analysis in A Metastatic Breast Cancer Patient Cohort. SR Yang, A van Brussel, A van de Stolpe, H van Ooijen, A Galimzianova, ... medicine 134 (7), e48-72, 2010 | 3 | 2010 |
Development of a Notch pathway assay and quantification of functional Notch pathway activity in T-cell acute lymphoblastic leukemia K Canté-Barrett, L Holtzer, H van Ooijen, R Hagelaar, V Cordo, ... bioRxiv, 2020.07. 10.183731, 2020 | 2 | 2020 |
Signal transduction pathway activity during neoadjuvant treatment in esophageal adenocarcinomas A Creemers, SL Meijer, M Stoffels, GKJ Hooijer, L Holtzer, H van Ooijen, ... Annals of Oncology 29, viii211, 2018 | 2 | 2018 |
Estrogen receptor pathway activity in endometrial carcinomas and its relation to tumor grade and recurrence LJ Van der Putten, A van Brussel, WJ van Weelden Proceedings of the American Association for Cancer Research Annual Meeting …, 2018 | 2 | 2018 |
FOXO transcriptional activity is associated with response to chemoradiation in EAC A Creemers, AP van der Zalm, A van de Stolpe, L Holtzer, M Stoffels, ... Journal of Translational Medicine 20 (1), 183, 2022 | 1 | 2022 |
Abstract P5-02-08: androgen receptor pathway activity and the ratio between androgen and estrogen receptor pathway activity in breast cancer subtypes A van de Stolpe, Y Wesseling-Rozendaal, MA de Inda, H van Ooijen, ... Cancer Research 80 (4_Supplement), P5-02-08-P5-02-08, 2020 | 1 | 2020 |
Androgen receptor pathway activity and the ratio between androgen and estrogen receptor pathway activity in breast cancer subtypes A van de Stolpe, Y Wesseling-Rozendaal, MA de Inda, H van Ooijen, ... CANCER RESEARCH 80 (4), 2020 | 1 | 2020 |
A Test to Quantify NOTCH Pathway Activity in T Cell Acute Lymphoblastic Leukemia Patients K Cante-Barrett, L Holtzer, H van Ooijen, R Hagelaar, W Verhaegh, ... Blood 134, 4661, 2019 | 1 | 2019 |
Assessing functional Androgen Receptor (AR) pathway activity using a computational model A Van Brussel, MA Inda, E Den Biezen, D van Strijp, J Wrobel, ... Annals of Oncology 28, v593, 2017 | 1 | 2017 |
Effects of flow and diffusion on blood coagulation in platelet poor plasma D Magnabosco, H van Ooijen, B Bakker, R van den Ham, L Formaggia | 1 | 2013 |
Development of a qPCR based ER signaling pathway activity test predictive for response to endocrine therapy in ER IHC positive breast cancer patients A Pierik, M Akse, H van Zon, A van Brussel, MA Inda, ... European Journal of Cancer 138, S88-S89, 2020 | | 2020 |
Development of quantitative multi-platform tests for easy readout of AR, ER, PI3K and MAPK pathway activity to unravel pathophysiology across cancer and tissue types M Akse, H van Ooijen, A Pierik, S van den Bosch, H van Zon, L Holtzer, ... Cancer Research 80 (16_Supplement), 4261-4261, 2020 | | 2020 |