| Hypothalamic POMC neurons promote cannabinoid-induced feeding M Koch, L Varela, JG Kim, JD Kim, F Hernández-Nuño, SE Simonds, ... Nature 519 (7541), 45-50, 2015 | 441 | 2015 |
| Leptin and insulin act on POMC neurons to promote the browning of white fat GT Dodd, S Decherf, K Loh, SE Simonds, F Wiede, E Balland, TL Merry, ... Cell 160 (1), 88-104, 2015 | 398 | 2015 |
| Leptin mediates the increase in blood pressure associated with obesity SE Simonds, JT Pryor, E Ravussin, FL Greenway, R Dileone, AM Allen, ... Cell 159 (6), 1404-1416, 2014 | 356 | 2014 |
| Leptin action in the dorsomedial hypothalamus increases sympathetic tone to brown adipose tissue in spite of systemic leptin resistance PJ Enriori, P Sinnayah, SE Simonds, CG Rudaz, MA Cowley Journal of Neuroscience 31 (34), 12189-12197, 2011 | 324 | 2011 |
| Elevated hypothalamic TCPTP in obesity contributes to cellular leptin resistance K Loh, A Fukushima, X Zhang, S Galic, D Briggs, PJ Enriori, S Simonds, ... Cell metabolism 14 (5), 684-699, 2011 | 247* | 2011 |
| Elevated hypothalamic TCPTP in obesity contributes to cellular leptin resistance K Loh, A Fukushima, X Zhang, S Galic, D Briggs, PJ Enriori, S Simonds, ... Cell metabolism 14 (5), 684-699, 2011 | 200 | 2011 |
| Impaired kisspeptin signaling decreases metabolism and promotes glucose intolerance and obesity KP Tolson, C Garcia, S Yen, S Simonds, A Stefanidis, A Lawrence, ... The Journal of clinical investigation 124 (7), 3075-3079, 2014 | 194 | 2014 |
| The melanocortin pathway and energy homeostasis: From discovery to obesity therapy GSH Yeo, DHM Chao, AM Siegert, ZM Koerperich, MD Ericson, ... Molecular metabolism 48, 101206, 2021 | 123 | 2021 |
| Insulin regulates POMC neuronal plasticity to control glucose metabolism GT Dodd, NJ Michael, RS Lee-Young, SP Mangiafico, JT Pryor, ... Elife 7, e38704, 2018 | 111 | 2018 |
| Addiction-like synaptic impairments in diet-induced obesity RM Brown, YM Kupchik, S Spencer, C Garcia-Keller, DC Spanswick, ... Biological psychiatry 81 (9), 797-806, 2017 | 106 | 2017 |
| Leptin stimulates neuropeptide Y and cocaine amphetamine-regulated transcript coexpressing neuronal activity in the dorsomedial hypothalamus in diet-induced obese mice SJ Lee, S Verma, SE Simonds, MA Kirigiti, P Kievit, SR Lindsley, A Loche, ... Journal of Neuroscience 33 (38), 15306-15317, 2013 | 83 | 2013 |
| Hypertension in obesity: is leptin the culprit? SE Simonds, MA Cowley Trends in neurosciences 36 (2), 121-132, 2013 | 69 | 2013 |
| Leptin reduces food intake via a dopamine D2 receptor-dependent mechanism SK Billes, SE Simonds, MA Cowley Molecular Metabolism 1 (1-2), 86-93, 2012 | 58 | 2012 |
| Celastrol promotes weight loss in diet-induced obesity by inhibiting the protein tyrosine phosphatases PTP1B and TCPTP in the hypothalamus E Kyriakou, S Schmidt, GT Dodd, K Pfuhlmann, SE Simonds, D Lenhart, ... Journal of Medicinal Chemistry 61 (24), 11144-11157, 2018 | 52 | 2018 |
| Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes C Clemmensen, S Jall, M Kleinert, C Quarta, T Gruber, J Reber, S Sachs, ... Nature communications 9 (1), 4304, 2018 | 51 | 2018 |
| A hypothalamic phosphatase switch coordinates energy expenditure with feeding GT Dodd, ZB Andrews, SE Simonds, NJ Michael, M DeVeer, JC Brüning, ... Cell metabolism 26 (2), 375-393. e7, 2017 | 51 | 2017 |
| α-Melanocyte stimulating hormone promotes muscle glucose uptake via melanocortin 5 receptors PJ Enriori, W Chen, MC Garcia-Rudaz, BE Grayson, AE Evans, ... Molecular metabolism 5 (10), 807-822, 2016 | 48 | 2016 |
| Leptin increasing sympathetic nerve outflow in obesity: A cure for obesity or a potential contributor to metabolic syndrome? SE Simonds, MA Cowley, PJ Enriori Adipocyte 1 (3), 177-181, 2012 | 47 | 2012 |
| Celastrol-induced weight loss is driven by hypophagia and independent from UCP1 K Pfuhlmann, SC Schriever, P Baumann, DG Kabra, L Harrison, ... Diabetes 67 (11), 2456-2465, 2018 | 43 | 2018 |
| The physiological effects of air pollution: particulate matter, physiology and disease JT Pryor, LO Cowley, SE Simonds Frontiers in Public Health 10, 882569, 2022 | 34 | 2022 |
