Targeting the STAT3 signaling pathway in cancer: role of synthetic and natural inhibitors KS Siveen, S Sikka, R Surana, X Dai, J Zhang, AP Kumar, BKH Tan, ... Biochimica et Biophysica Acta (BBA)-reviews on cancer 1845 (2), 136-154, 2014 | 763 | 2014 |
Role of macrophages in tumour progression KS Siveen, G Kuttan Immunology letters 123 (2), 97-102, 2009 | 454 | 2009 |
Analysis of the intricate relationship between chronic inflammation and cancer EZP Chai, KS Siveen, MK Shanmugam, F Arfuso, G Sethi Biochemical Journal 468 (1), 1-15, 2015 | 214 | 2015 |
Vascular endothelial growth factor (VEGF) signaling in tumour vascularization: potential and challenges K Sivaraman Siveen, K Prabhu, R Krishnankutty, S Kuttikrishnan, ... Current vascular pharmacology 15 (4), 339-351, 2017 | 204 | 2017 |
Isorhamnetin augments the anti-tumor effect of capeciatbine through the negative regulation of NF-κB signaling cascade in gastric cancer KA Manu, MK Shanmugam, L Ramachandran, F Li, KS Siveen, ... Cancer Letters 363 (1), 28-36, 2015 | 160 | 2015 |
RAS-mediated oncogenic signaling pathways in human malignancies AQ Khan, S Kuttikrishnan, KS Siveen, KS Prabhu, M Shanmugakonar, ... Seminars in cancer biology 54, 1-13, 2019 | 159 | 2019 |
Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-κB regulated gene products in multiple myeloma xenograft mouse … KS Siveen, N Mustafa, F Li, R Kannaiyan, KS Ahn, AP Kumar, WJ Chng, ... Oncotarget 5 (3), 634, 2014 | 156 | 2014 |
γ-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model KS Siveen, KS Ahn, TH Ong, MK Shanmugam, F Li, WN Yap, AP Kumar, ... Oncotarget 5 (7), 1897, 2014 | 154 | 2014 |
Nimbolide-induced oxidative stress abrogates STAT3 signaling cascade and inhibits tumor growth in transgenic adenocarcinoma of mouse prostate model J Zhang, KS Ahn, C Kim, MK Shanmugam, KS Siveen, F Arfuso, ... Antioxidants & redox signaling 24 (11), 575-589, 2016 | 153 | 2016 |
Simvastatin sensitizes human gastric cancer xenograft in nude mice to capecitabine by suppressing nuclear factor-kappa B-regulated gene products KA Manu, MK Shanmugam, F Li, L Chen, KS Siveen, KS Ahn, AP Kumar, ... Journal of molecular medicine 92, 267-276, 2014 | 152 | 2014 |
Isorhamnetin inhibits proliferation and invasion and induces apoptosis through the modulation of peroxisome proliferator-activated receptor γ activation pathway in gastric cancer L Ramachandran, KA Manu, MK Shanmugam, F Li, KS Siveen, S Vali, ... Journal of Biological Chemistry 287 (45), 38028-38040, 2012 | 151 | 2012 |
Targeting acute myeloid leukemia stem cell signaling by natural products KS Siveen, S Uddin, RM Mohammad Molecular cancer 16, 1-12, 2017 | 150 | 2017 |
Role of non receptor tyrosine kinases in hematological malignances and its targeting by natural products KS Siveen, KS Prabhu, IW Achkar, S Kuttikrishnan, S Shyam, AQ Khan, ... Molecular cancer 17, 1-21, 2018 | 129 | 2018 |
Silymarin and hepatocellular carcinoma: a systematic, comprehensive, and critical review JK Mastron, KS Siveen, G Sethi, A Bishayee Anti-Cancer Drugs 26 (5), 475-486, 2015 | 126 | 2015 |
Oleanane triterpenoids in the prevention and therapy of breast cancer: current evidence and future perspectives NR Parikh, A Mandal, D Bhatia, KS Siveen, G Sethi, A Bishayee Phytochemistry reviews 13, 793-810, 2014 | 117 | 2014 |
microRNAs in breast cancer: regulatory roles governing the hallmarks of cancer JN Goh, SY Loo, A Datta, KS Siveen, WN Yap, W Cai, EM Shin, C Wang, ... Biological Reviews 91 (2), 409-428, 2016 | 114 | 2016 |
Ascochlorin, an isoprenoid antibiotic inhibits growth and invasion of hepatocellular carcinoma by targeting STAT3 signaling cascade through the induction of PIAS3 X Dai, KS Ahn, C Kim, KS Siveen, TH Ong, MK Shanmugam, F Li, J Shi, ... Molecular oncology 9 (4), 818-833, 2015 | 106 | 2015 |
Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy AA Bhat, S Nisar, S Maacha, TC Carneiro-Lobo, S Akhtar, KS Siveen, ... Molecular cancer 20, 1-20, 2021 | 87 | 2021 |
Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite downregulation of proliferative biomarkers F Li, MK Shanmugam, KS Siveen, F Wang, TH Ong, SY Loo, ... Oncotarget 6 (7), 5147, 2015 | 83 | 2015 |
Negative regulation of signal transducer and activator of transcription-3 signalling cascade by lupeol inhibits growth and induces apoptosis in hepatocellular carcinoma cells KS Siveen, AH Nguyen, JH Lee, F Li, SS Singh, AP Kumar, G Low, S Jha, ... British journal of cancer 111 (7), 1327-1337, 2014 | 83 | 2014 |