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Thomas A Gerken
Thomas A Gerken
Verified email at case.edu
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Cited by
Cited by
Year
Control of mucin-type O-glycosylation: a classification of the polypeptide GalNAc-transferase gene family
EP Bennett, U Mandel, H Clausen, TA Gerken, TA Fritz, LA Tabak
Glycobiology 22 (6), 736-756, 2012
9062012
Role of glycosylation on the conformation and chain dimensions of O-linked glycoproteins: light-scattering studies of ovine submaxillary mucin
R Shogren, TA Gerken, N Jentoft
Biochemistry 28 (13), 5525-5536, 1989
3161989
Effects of glycosylation on the conformation and dynamics of O-linked glycoproteins: carbon-13 NMR studies of ovine submaxillary mucin
TA Gerken, KJ Butenhof, R Shogren
Biochemistry 28 (13), 5536-5543, 1989
1951989
Emerging paradigms for the initiation of mucin-type protein O-glycosylation by the polypeptide GalNAc transferase family of glycosyltransferases
TA Gerken, O Jamison, CL Perrine, JC Collette, H Moinova, L Ravi, ...
Journal of Biological Chemistry 286 (16), 14493-14507, 2011
1732011
Inactivating germ-line and somatic mutations in polypeptide N-acetylgalactosaminyltransferase 12 in human colon cancers
K Guda, H Moinova, J He, O Jamison, L Ravi, L Natale, J Lutterbaugh, ...
Proceedings of the National Academy of Sciences 106 (31), 12921-12925, 2009
1502009
Thermodynamics of multivalent carbohydrate− lectin cross-linking interactions: Importance of entropy in the bind and jump mechanism
TK Dam, TA Gerken, CF Brewer
Biochemistry 48 (18), 3822-3827, 2009
1332009
Binding studies of α-GalNAc-specific lectins to the α-GalNAc (Tn-antigen) form of porcine submaxillary mucin and its smaller fragments
TK Dam, TA Gerken, BS Cavada, KS Nascimento, TR Moura, CF Brewer
Journal of biological chemistry 282 (38), 28256-28263, 2007
1262007
Deconvoluting the functions of polypeptide N-α-acetylgalactosaminyltransferase family members by glycopeptide substrate profiling
MR Pratt, HC Hang, KG Ten Hagen, J Rarick, TA Gerken, LA Tabak, ...
Chemistry & biology 11 (7), 1009-1016, 2004
1182004
Probing polypeptide GalNAc-transferase isoform substrate specificities by in vitro analysis
Y Kong, HJ Joshi, KTBG Schjoldager, TD Madsen, TA Gerken, ...
Glycobiology 25 (1), 55-65, 2015
1072015
A novel approach for chemically deglycosylating O-linked glycoproteins. The deglycosylation of submaxillary and respiratory mucins
TA Gerken, R Gupta, N Jentoft
Biochemistry 31 (3), 639-648, 1992
1071992
Identification of common and unique peptide substrate preferences for the UDP-GalNAc: polypeptide α-N-acetylgalactosaminyltransferases T1 and T2 derived from oriented random …
TA Gerken, J Raman, TA Fritz, O Jamison
Journal of biological chemistry 281 (43), 32403-32416, 2006
1062006
Determination of the site-specific O-glycosylation pattern of the porcine submaxillary mucin tandem repeat glycopeptide: Model proposed for the polypeptide: GalNAc transferase …
TA Gerken, CL Owens, M Pasumarthy
Journal of Biological Chemistry 272 (15), 9709-9719, 1997
1031997
Quantification of human β-defensin-2 and-3 in body fluids: application for studies of innate immunity
SK Ghosh, TA Gerken, KM Schneider, Z Feng, TS McCormick, ...
Clinical chemistry 53 (4), 757-765, 2007
1022007
13C NMR studies of ribonuclease A methylated with [13C] Formaldehyde.
JE Jentoft, N Jentoft, TA Gerken, DG Dearborn
Journal of Biological Chemistry 254 (11), 4366-4370, 1979
931979
UDP-N-acetyl-α-d-galactosamine:polypeptide N-acetylgalactosaminyltransferases: Completion of the family tree
J Raman, Y Guan, CL Perrine, TA Gerken, LA Tabak
Glycobiology 22 (6), 768-777, 2012
912012
Functional characterization and expression analysis of members of the UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase family from Drosophila melanogaster
KG Ten Hagen, DT Tran, TA Gerken, DS Stein, Z Zhang
Journal of Biological Chemistry 278 (37), 35039-35048, 2003
902003
The catalytic and lectin domains of UDP-GalNAc: polypeptide α-N-acetylgalactosaminyltransferase function in concert to direct glycosylation site selection
J Raman, TA Fritz, TA Gerken, O Jamison, D Live, M Liu, LA Tabak
Journal of biological chemistry 283 (34), 22942-22951, 2008
872008
The lectin domain of the polypeptide GalNAc transferase family of glycosyltransferases (ppGalNAc Ts) acts as a switch directing glycopeptide substrate glycosylation in an N-or …
TA Gerken, L Revoredo, JJC Thome, LA Tabak, MB Vester-Christensen, ...
Journal of Biological Chemistry 288 (27), 19900-19914, 2013
832013
Mucin-type O-glycosylation is controlled by short-and long-range glycopeptide substrate recognition that varies among members of the polypeptide GalNAc transferase family
L Revoredo, S Wang, EP Bennett, H Clausen, KW Moremen, DL Jarvis, ...
Glycobiology 26 (4), 360-376, 2016
822016
[13C] Methylated ribonuclease A. 13C NMR studies of the interaction of lysine 41 with active site ligands.
JE Jentoft, TA Gerken, N Jentoft, DG Dearborn
Journal of Biological Chemistry 256 (1), 231-236, 1981
811981
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