| Therapeutic potential of AAV-mediated MMP-3 secretion from corneal endothelium in treating glaucoma J O’Callaghan, DE Crosbie, PS Cassidy, JM Sherwood, C Flügel-Koch, ... Human molecular genetics 26 (7), 1230-1246, 2017 | 70 | 2017 |
| Open-angle glaucoma: therapeutically targeting the extracellular matrix of the conventional outflow pathway J O’Callaghan, PS Cassidy, P Humphries Expert opinion on therapeutic targets 21 (11), 1037-1050, 2017 | 48 | 2017 |
| Enhancement of outflow facility in the murine eye by targeting selected tight-junctions of Schlemm’s canal endothelia LCS Tam, E Reina-Torres, JM Sherwood, PS Cassidy, DE Crosbie, ... Scientific reports 7 (1), 40717, 2017 | 29 | 2017 |
| Manipulating ocular endothelial tight junctions: Applications in treatment of retinal disease pathology and ocular hypertension M Campbell, PS Cassidy, J O'Callaghan, DE Crosbie, P Humphries Progress in Retinal and Eye Research 62, 120-133, 2018 | 18 | 2018 |
| Fibrotic changes to Schlemm’s canal endothelial cells in glaucoma RA Kelly, KM Perkumas, M Campbell, GJ Farrar, WD Stamer, ... International Journal of Molecular Sciences 22 (17), 9446, 2021 | 15 | 2021 |
| Matrix mechanotransduction via yes-associated protein in human lamina cribrosa cells in glaucoma R Murphy, M Irnaten, A Hopkins, J O'Callaghan, WD Stamer, AF Clark, ... Investigative Ophthalmology & Visual Science 63 (1), 16-16, 2022 | 13 | 2022 |
| siRNA targeting Schlemm’s canal endothelial tight junctions enhances outflow facility and reduces IOP in a steroid-induced OHT rodent model PS Cassidy, RA Kelly, E Reina-Torres, JM Sherwood, MM Humphries, ... Molecular Therapy-Methods & Clinical Development 20, 86-94, 2021 | 11 | 2021 |
| Blood–brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairment C Greene, R Connolly, D Brennan, A Laffan, E O’Keeffe, L Zaporojan, ... Nature Neuroscience, 1-12, 2024 | 7 | 2024 |
| Matrix metalloproteinase-3 (MMP-3)–mediated gene therapy for glaucoma J O’Callaghan, C Delaney, M O’Connor, J van Batenburg-Sherwood, ... Science Advances 9 (16), eadf6537, 2023 | 7 | 2023 |
| Reduced humidity experienced by mice in vivo coincides with reduced outflow facility measured ex vivo E Reina-Torres, JA Bertrand, J O'Callaghan, JM Sherwood, P Humphries, ... Experimental eye research 186, 107745, 2019 | 6 | 2019 |
| Intracameral delivery of AAV to corneal endothelium for expression of secretory proteins J O’Callaghan, M Campbell, P Humphries Adeno-Associated Virus Vectors: Design and Delivery, 263-270, 2019 | 3 | 2019 |
| A Novel Gene-based Therapy for Glaucoma: From Discovery to Preclinical Development J O'Callaghan Trinity College Dublin, 2018 | 1 | 2018 |
| Circadian regulation of the inner blood retina barrier as a mechanism for the development of dry AMD. M O'Riordan, N Hudson, J O'Callaghan, M Campbell, M Cahill Investigative Ophthalmology & Visual Science 64 (8), 2756-2756, 2023 | | 2023 |
| Near-Complete Drusen Resolution With Brolucizumab: A Mechanism for Proinflammatory Mediated Drusen Clearance? M O'Riordan, N Hudson, J O'Callaghan, M Campbell, M Cahill Ophthalmic Surgery, Lasers and Imaging Retina 54 (6), 371-374, 2023 | | 2023 |
| Compositions and methods for ocular therapy J O'callaghan, TW Chalberg, M Lawrence, A Keravala, M Campbell, ... US Patent App. 17/765,368, 2022 | | 2022 |
| Characterisation of three novel animal models of geographic atrophy N Hudson, J O'Callaghan, C Delaney, A Reddy, K Byrne, S Doyle, ... Investigative Ophthalmology & Visual Science 63 (7), 3478-3478, 2022 | | 2022 |
| Examining inner blood retina barrier function in rare neurological conditions D Harford, J O'Callaghan, C Delaney, N Hudson, R Connolly, S Doyle, ... Investigative Ophthalmology & Visual Science 63 (7), 1739–F0199-1739–F0199, 2022 | | 2022 |
| Circadian regulation of the inner blood retinal barrier: a paradigm for dry age-related macular degeneration development F O'Leary, N Hudson, J O'Callaghan, M Campbell, M Cahill Investigative Ophthalmology & Visual Science 63 (7), 347–F0178-347–F0178, 2022 | | 2022 |
| Recombinant Human MMP-3 Increases Outflow Facility In Vivo in Non-Human Primates and Ex Vivo in Human Cadaver Eyes J O'Callaghan, M Lawrence, M O'Connor, J Sherwood, A Keravala, ... Investigative Ophthalmology & Visual Science 63 (7), 2826–A0342-2826–A0342, 2022 | | 2022 |
| Safety and Tolerability of AAV in the Anterior Chamber: A Platform for Gene Therapy M Lawrence, J O'Callaghan, M O'Connor, T Chalberg, A Keravala, ... Investigative Ophthalmology & Visual Science 63 (7), 2849–A0372-2849–A0372, 2022 | | 2022 |
