| Cancer genome landscapes B Vogelstein, N Papadopoulos, VE Velculescu, S Zhou, LA Diaz, ... science 339 (6127), 1546-1558, 2013 | 6108 | 2013 |
| PD-1 blockade in tumors with mismatch-repair deficiency DT Le, JN Uram, H Wang, BR Bartlett, H Kemberling, AD Eyring, ... New England Journal of Medicine 372 (26), 2509-2520, 2015 | 5641 | 2015 |
| An integrated genomic analysis of human glioblastoma multiforme DW Parsons, S Jones, X Zhang, JCH Lin, RJ Leary, P Angenendt, ... science 321 (5897), 1807-1812, 2008 | 5500 | 2008 |
| Detection of circulating tumor DNA in early-and late-stage human malignancies C Bettegowda, M Sausen, RJ Leary, I Kinde, Y Wang, N Agrawal, ... Science translational medicine 6 (224), 224ra24-224ra24, 2014 | 2839 | 2014 |
| Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade DT Le, JN Durham, KN Smith, H Wang, BR Bartlett, LK Aulakh, S Lu, ... Science 357 (6349), 409-413, 2017 | 2775 | 2017 |
| Circulating mutant DNA to assess tumor dynamics F Diehl, K Schmidt, MA Choti, K Romans, S Goodman, M Li, K Thornton, ... Nature medicine 14 (9), 985-990, 2008 | 1891 | 2008 |
| Liquid biopsies: genotyping circulating tumor DNA LA Diaz Jr, A Bardelli Journal of clinical oncology 32 (6), 579, 2014 | 1591 | 2014 |
| The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers LA Diaz Jr, RT Williams, J Wu, I Kinde, JR Hecht, J Berlin, B Allen, I Bozic, ... Nature 486 (7404), 537-540, 2012 | 1551 | 2012 |
| DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors Y Jiao, C Shi, BH Edil, RF De Wilde, DS Klimstra, A Maitra, RD Schulick, ... Science 331 (6021), 1199-1203, 2011 | 1415 | 2011 |
| Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma S Jones, TL Wang, IM Shih, TL Mao, K Nakayama, R Roden, R Glas, ... Science 330 (6001), 228-231, 2010 | 1109 | 2010 |
| Detection and quantification of mutations in the plasma of patients with colorectal tumors F Diehl, M Li, D Dressman, Y He, D Shen, S Szabo, LA Diaz, ... Proceedings of the National Academy of Sciences 102 (45), 16368-16373, 2005 | 1098 | 2005 |
| The colorectal microRNAome JM Cummins, Y He, RJ Leary, R Pagliarini, LA Diaz, T Sjoblom, O Barad, ... Proceedings of the National Academy of Sciences 103 (10), 3687-3692, 2006 | 1097 | 2006 |
| TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal PJ Killela, ZJ Reitman, Y Jiao, C Bettegowda, N Agrawal, LA Diaz, ... Proceedings of the National Academy of Sciences 110 (15), 6021-6026, 2013 | 1075 | 2013 |
| Detection and localization of surgically resectable cancers with a multi-analyte blood test JD Cohen, L Li, Y Wang, C Thoburn, B Afsari, L Danilova, C Douville, ... Science 359 (6378), 926-930, 2018 | 1052 | 2018 |
| Fulminant myocarditis with combination immune checkpoint blockade DB Johnson, JM Balko, ML Compton, S Chalkias, J Gorham, Y Xu, ... New England Journal of Medicine 375 (18), 1749-1755, 2016 | 967 | 2016 |
| Mutant PIK3CA promotes cell growth and invasion of human cancer cells Y Samuels, LA Diaz Jr, O Schmidt-Kittler, JM Cummins, L DeLong, ... Cancer cell 7 (6), 561-573, 2005 | 928 | 2005 |
| Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells J Yun, C Rago, I Cheong, R Pagliarini, P Angenendt, H Rajagopalan, ... Science 325 (5947), 1555-1559, 2009 | 807 | 2009 |
| Recurrent GNAS mutations define an unexpected pathway for pancreatic cyst development J Wu, H Matthaei, A Maitra, M Dal Molin, LD Wood, JR Eshleman, ... Science translational medicine 3 (92), 92ra66-92ra66, 2011 | 698 | 2011 |
| Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer J Tie, Y Wang, C Tomasetti, L Li, S Springer, I Kinde, N Silliman, M Tacey, ... Science translational medicine 8 (346), 346ra92-346ra92, 2016 | 669 | 2016 |
| Primary resistance to PD-1 blockade mediated by JAK1/2 mutations DS Shin, JM Zaretsky, H Escuin-Ordinas, A Garcia-Diaz, S Hu-Lieskovan, ... Cancer discovery 7 (2), 188-201, 2017 | 593 | 2017 |
Bert VogelsteinJohns HopkinsVerified email at jhmi.edu
