The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span K Jia, D Chen, DL Riddle Oxford University Press for The Company of Biologists Limited 131 (16), 3897 …, 2004 | 879 | 2004 |
With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging P Kapahi, D Chen, AN Rogers, SD Katewa, PWL Li, EL Thomas, L Kockel Cell metabolism 11 (6), 453-465, 2010 | 782 | 2010 |
Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans KZ Pan, JE Palter, AN Rogers, A Olsen, D Chen, GJ Lithgow, P Kapahi Aging cell 6 (1), 111-119, 2007 | 567 | 2007 |
HIF-1 Modulates Dietary Restriction-Mediated Lifespan Extension via IRE-1 in Caenorhabditis elegans D Chen, EL Thomas, P Kapahi PLoS genetics 5 (5), e1000486, 2009 | 300 | 2009 |
Longevity determined by developmental arrest genes in Caenorhabditis elegans D Chen, KZ Pan, JE Palter, P Kapahi Aging cell 6 (4), 525-533, 2007 | 153 | 2007 |
Germline signaling mediates the synergistically prolonged longevity produced by double mutations in daf-2 and rsks-1 in C. elegans D Chen, PWL Li, BA Goldstein, W Cai, EL Thomas, F Chen, AE Hubbard, ... Cell reports 5 (6), 1600-1610, 2013 | 143 | 2013 |
A human protein interaction network shows conservation of aging processes between human and invertebrate species R Bell, A Hubbard, R Chettier, D Chen, JP Miller, P Kapahi, ... PLoS genetics 5 (3), e1000414, 2009 | 142 | 2009 |
Life span extension via eIF4G inhibition is mediated by posttranscriptional remodeling of stress response gene expression in C. elegans AN Rogers, D Chen, G McColl, G Czerwieniec, K Felkey, BW Gibson, ... Cell metabolism 14 (1), 55-66, 2011 | 136 | 2011 |
Construction of a germline-specific RNAi tool in C. elegans L Zou, D Wu, X Zang, Z Wang, Z Wu, D Chen Scientific reports 9 (1), 2354, 2019 | 66 | 2019 |
A systems approach to reverse engineer lifespan extension by dietary restriction L Hou, D Wang, DI Chen, YI Liu, Y Zhang, H Cheng, C Xu, NA Sun, ... Cell metabolism 23 (3), 529-540, 2016 | 64 | 2016 |
Translational regulation of non-autonomous mitochondrial stress response promotes longevity J Lan, JA Rollins, X Zang, D Wu, L Zou, Z Wang, C Ye, Z Wu, P Kapahi, ... Cell reports 28 (4), 1050-1062. e6, 2019 | 60 | 2019 |
A SNP of bacterial blc disturbs gut lysophospholipid homeostasis and induces inflammation through epithelial barrier disruption D Zou, J Pei, J Lan, H Sang, H Chen, H Yuan, D Wu, Y Zhang, Y Wang, ... EBioMedicine 52, 2020 | 35 | 2020 |
β-Dihydroagarofuran-type sesquiterpenes from the seeds of Celastrus monospermus and their lifespan-extending effects on the nematode Caenorhabditis elegans L Gao, R Zhang, J Lan, R Ning, D Wu, D Chen, W Zhao Journal of Natural Products 79 (12), 3039-3046, 2016 | 28 | 2016 |
Using microfluidic impedance cytometry to measure C. elegans worms and identify their developmental stages Z Zhu, W Chen, B Tian, Y Luo, J Lan, D Wu, D Chen, Z Wang, D Pan Sensors and Actuators B: Chemical 275, 470-482, 2018 | 23 | 2018 |
daf-31 Encodes the Catalytic Subunit of N Alpha-Acetyltransferase that Regulates Caenorhabditis elegans Development, Metabolism and Adult Lifespan D Chen, J Zhang, J Minnerly, T Kaul, DL Riddle, K Jia PLoS Genetics 10 (10), e1004699, 2014 | 23 | 2014 |
Function of the PHA-4/FOXA transcription factor during C. eleganspost-embryonic development D Chen, DL Riddle BMC Developmental Biology 8, 1-10, 2008 | 21 | 2008 |
LIN‐28 balances longevity and germline stem cell number in Caenorhabditis elegans through let‐7/AKT/DAF‐16 axis D Wang, L Hou, S Nakamura, M Su, F Li, W Chen, Y Yan, CD Green, ... Aging Cell 16 (1), 113-124, 2017 | 20 | 2017 |
An antagonistic pleiotropic gene regulates the reproduction and longevity tradeoff D Wu, Z Wang, J Huang, L Huang, S Zhang, R Zhao, W Li, D Chen, G Ou Proceedings of the National Academy of Sciences 119 (18), e2120311119, 2022 | 12 | 2022 |
Molecular mechanisms of dietary restriction in aging—insights from Caenorhabditis elegans research JF Lan, X Zhang, D Chen Science China Life Sciences 58, 352-358, 2015 | 11 | 2015 |
H3K9me1/2 methylation limits the lifespan of daf-2 mutants in C. elegans M Huang, M Hong, X Hou, C Zhu, D Chen, X Chen, S Guang, X Feng Elife 11, e74812, 2022 | 8 | 2022 |