Agustín Lahoz
Agustín Lahoz
Instituto de Investigación Sanitaria Hospital La Fe
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Cell lines: a tool for in vitro drug metabolism studies
MJ Gomez-Lechon, MT Donato, A Lahoz, JV Castell
Current drug metabolism 9 (1), 1-11, 2008
Stable expression, activity, and inducibility of cytochromes P450 in differentiated HepaRG cells
S Anthérieu, C Chesné, R Li, S Camus, A Lahoz, L Picazo, M Turpeinen, ...
Drug Metabolism and Disposition 38 (3), 516-525, 2010
Targeted profiling of circulating and hepatic bile acids in human, mouse, and rat using a UPLC-MRM-MS-validated method
JC García-Cañaveras, MT Donato, JV Castell, A Lahoz
Journal of lipid research 53 (10), 2231-2241, 2012
Mammalian cell metabolomics: experimental design and sample preparation
Z León, JC García‐Cañaveras, MT Donato, A Lahoz
Electrophoresis 34 (19), 2762-2775, 2013
Unprecedented Blue Intrinsic Photoluminescence from Hyperbranched and Linear Polyethylenimines: Polymer Architectures and pH‐Effects
L Pastor‐Pérez, Y Chen, Z Shen, A Lahoz, SE Stiriba
Macromolecular rapid communications 28 (13), 1404-1409, 2007
Potential impact of steatosis on cytochrome P450 enzymes of human hepatocytes isolated from fatty liver grafts
MT Donato, A Lahoz, N Jiménez, G Pérez, A Serralta, J Mir, JV Castell, ...
Drug metabolism and disposition 34 (9), 1556-1562, 2006
A score model for the continuous grading of early allograft dysfunction severity
E Pareja, M Cortes, D Hervas, J Mir, A Valdivieso, JV Castell, A Lahoz
Liver Transplantation 21 (1), 38-46, 2015
A comprehensive untargeted metabonomic analysis of human steatotic liver tissue by RP and HILIC chromatography coupled to mass spectrometry reveals important metabolic alterations
JC García-Canaveras, MT Donato, JV Castell, A Lahoz
Journal of proteome research 10 (10), 4825-4834, 2011
Development of a multiparametric cell-based protocol to screen and classify the hepatotoxicity potential of drugs
L Tolosa, S Pinto, MT Donato, A Lahoz, JV Castell, JE O’Connor, ...
Toxicological Sciences 127 (1), 187-198, 2012
In vitro evaluation of potential hepatotoxicity induced by drugs
MJ Gomez-Lechon, A Lahoz, L Gombau, JV Castell, MT Donato
Current pharmaceutical design 16 (17), 1963-1977, 2010
Polypodium leucotomos extract: antioxidant activity and disposition
L Gombau, F Garcia, A Lahoz, M Fabre, P Roda-Navarro, P Majano, ...
Toxicology in vitro 20 (4), 464-471, 2006
Assessing the metabolic competence of sandwich-cultured mouse primary hepatocytes
K Mathijs, AS Kienhuis, KJJ Brauers, DGJ Jennen, A Lahoz, ...
Drug Metabolism and Disposition 37 (6), 1305-1311, 2009
Validated assay for studying activity profiles of human liver UGTs after drug exposure: inhibition and induction studies
MT Donato, S Montero, JV Castell, MJ Gómez-Lechón, A Lahoz
Analytical and bioanalytical chemistry 396 (6), 2251-2263, 2010
Human Embryonic Stem Cell Derived Hepatocyte-Like Cells as a Tool for In Vitro Hazard Assessment of Chemical Carcinogenicity
R Yildirimman, G Brolén, M Vilardell, G Eriksson, J Synnergren, ...
Toxicological Sciences 124 (2), 278-290, 2011
Sequential hepatogenic transdifferentiation of adipose tissue-derived stem cells: relevance of different extracellular signaling molecules, transcription factors involved, and …
A Bonora-Centelles, R Jover, V Mirabet, A Lahoz, F Carbonell, JV Castell, ...
Cell transplantation 18 (12), 1319-1340, 2009
Metabolomics discloses donor liver biomarkers associated with early allograft dysfunction
M Cortes, E Pareja, JC García-Cañaveras, M Teresa Donato, S Montero, ...
Journal of Hepatology, 2014
Chemometric approaches to improve PLSDA model outcome for predicting human non-alcoholic fatty liver disease using UPLC-MS as a metabolic profiling tool
G Quintás, N Portillo, JC García-Cañaveras, JV Castell, A Ferrer, A Lahoz
Metabolomics 8 (1), 86-98, 2012
Interactions of polyphenols with the P450 system: possible implications on human therapeutics.
I Rodeiro, MT Donato, A Lahoz, G Garrido, R Delgado, MJ Gómez-Lechón
Mini reviews in medicinal chemistry 8 (2), 97-106, 2008
Photoreaction between 2-benzoylthiophene and phenol or indole
J Pérez-Prieto, F Boscá, RE Galian, A Lahoz, LR Domingo, MA Miranda
The Journal of Organic Chemistry 68 (13), 5104-5113, 2003
A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway
JM Ghergurovich, JC García-Cañaveras, J Wang, E Schmidt, Z Zhang, ...
Nature chemical biology 16 (7), 731-739, 2020
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