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Michael O'Dwyer
Michael O'Dwyer
Senior Lecturer in Intensive Care Medicine, Queen Mary University of London
Bestätigte E-Mail-Adresse bei qmul.ac.uk
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Jahr
Septic shock is correlated with asymmetrical dimethyl arginine levels, which may be influenced by a polymorphism in the dimethylarginine dimethylaminohydrolase II gene: a …
MJ O'Dwyer, F Dempsey, V Crowley, DP Kelleher, R McManus, T Ryan
Critical Care 10 (5), R139, 2006
1292006
Features of postoperative immune suppression are reversible with interferon gamma and independent of interleukin-6 Pathways
ER Longbottom, HDT Torrance, HC Owen, PC Fragkou, CJ Hinds, ...
Annals of surgery 264 (2), 370-377, 2016
1042016
The perioperative immune response
MJ O’Dwyer, HC Owen, HDT Torrance
Current opinion in critical care 21 (4), 336-342, 2015
832015
Systemic inflammatory response syndrome after major abdominal surgery predicted by early upregulation of TLR4 and TLR5
R Lahiri, Y Derwa, Z Bashir, E Giles, HDT Torrance, HC Owen, ...
Annals of surgery 263 (5), 1028-1037, 2016
632016
Association between gene expression biomarkers of immunosuppression and blood transfusion in severely injured polytrauma patients
HDT Torrance, K Brohi, RM Pearse, CA Mein, E Wozniak, JR Prowle, ...
Annals of surgery 261 (4), 751-759, 2015
602015
The occurrence of severe sepsis and septic shock are related to distinct patterns of cytokine gene expression
MJ O'Dwyer, AK Mankan, P Stordeur, B O'Connell, E Duggan, M White, ...
Shock 26 (4), 5-6, 2006
582006
Does major surgery induce immune suppression and increase the risk of postoperative infection?
HDT Torrance, RM Pearse, MJ O’Dwyer
Current Opinion in Anesthesiology 29 (3), 376-383, 2016
522016
Expression of hereditary hemochromatosis C282Y HFE protein in HEK293 cells activates specific endoplasmic reticulum stress responses
MW Lawless, AK Mankan, M White, MJ O'Dwyer, S Norris
BMC cell biology 8 (1), 30, 2007
502007
Perioperative blood transfusion is associated with a gene transcription profile characteristic of immunosuppression: a prospective cohort study
PC Fragkou, HD Torrance, RM Pearse, GL Ackland, JR Prowle, HC Owen, ...
Critical care 18 (5), 541, 2014
452014
The human response to infection is associated with distinct patterns of interleukin 23 and interleukin 27 expression
MJ O’Dwyer, AK Mankan, M White, MW Lawless, P Stordeur, B O’Connell, ...
Intensive care medicine 34 (4), 683-691, 2008
382008
Hospital-acquired pneumonia after lung resection surgery is associated with characteristic cytokine gene expression
M White, I Martin-Loeches, MW Lawless, MJ O’Dwyer, DG Doherty, ...
CHEST Journal 139 (3), 626-632, 2011
322011
Tumor necrosis factor-α and interleukin-10 gene expression in peripheral blood mononuclear cells after cardiac surgery
E Duggan, E Caraher, K Gately, M O'Dwyer, E McGovern, D Kelleher, ...
Critical care medicine 34 (8), 2134-2139, 2006
322006
Gene polymorphism and requirement for vasopressor infusion after cardiac surgery
R Ryan, J Thornton, E Duggan, E McGovern, MJ O’Dwyer, AW Ryan, ...
The Annals of thoracic surgery 82 (3), 895-901, 2006
312006
Transforming growth factor β-1 and interleukin-17 gene transcription in peripheral blood mononuclear cells and the human response to infection
M White, MW Lawless, MJ O’Dwyer, R Grealy, BO Connell, P Stordeur, ...
Cytokine 50 (3), 322-327, 2010
282010
The detection of microbial DNA but not cultured bacteria is associated with increased mortality in patients with suspected sepsis—a prospective multi-centre European …
MJ O’Dwyer, MH Starczewska, J Schrenzel, K Zacharowski, DJ Ecker, ...
Clinical Microbiology and Infection, 2016
272016
Elevated MCP‐1 serum levels are associated with the H63D mutation and not the C282Y mutation in hereditary hemochromatosis
MW Lawless, M White, AK Mankan, MJ O’Dwyer, S Norris
Tissue antigens 70 (4), 294-300, 2007
262007
Changes in gene expression following trauma are related to the age of transfused packed red blood cells
HDT Torrance, ME Vivian, K Brohi, JR Prowle, RM Pearse, HC Owen, ...
Journal of Trauma and Acute Care Surgery 78 (3), 535-542, 2015
242015
Coagulopathy after cardiac surgery may be influenced by a functional plasminogen activator inhibitor polymorphism
E Duggan, MJ O’dwyer, E Caraher, D Diviney, E McGovern, D Kelleher, ...
Anesthesia & Analgesia 104 (6), 1343-1347, 2007
242007
Epigenetic regulatory pathways involving microRNAs may modulate the host immune response following major trauma
HC Owen, HDT Torrance, TF Jones, RM Pearse, CJ Hinds, K Brohi, ...
Journal of Trauma and Acute Care Surgery 79 (5), 766-772, 2015
162015
Characterization of tumour necrosis factor‐alpha genetic variants and mRNA expression in patients with severe sepsis
MJ O'Dwyer, AK Mankan, AW Ryan, MW Lawless, P Stordeur, D Kelleher, ...
International journal of immunogenetics 35 (4‐5), 279-285, 2008
152008
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