Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease L Jostins, S Ripke, RK Weersma, RH Duerr, DP McGovern, KY Hui, ... Nature 491 (7422), 119, 2012 | 3173 | 2012 |
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci A Franke, DPB McGovern, JC Barrett, K Wang, GL Radford-Smith, ... Nature genetics 42 (12), 1118, 2010 | 2332 | 2010 |
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis S Sawcer, G Hellenthal, M Pirinen, CCA Spencer, NA Patsopoulos, ... Nature 476 (7359), 214, 2011 | 1902 | 2011 |
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1 J Hampe, A Franke, P Rosenstiel, A Till, M Teuber, K Huse, M Albrecht, ... Nature genetics 39 (2), 207, 2007 | 1822 | 2007 |
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47 CA Anderson, G Boucher, CW Lees, A Franke, M D'Amato, KD Taylor, ... Nature genetics 43 (3), 246, 2011 | 1253 | 2011 |
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47 CA Anderson, G Boucher, CW Lees, A Franke, M D'Amato, KD Taylor, ... Nature genetics 43 (3), 246, 2011 | 1245 | 2011 |
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47 CA Anderson, G Boucher, CW Lees, A Franke, M D'Amato, KD Taylor, ... Nature genetics 43 (3), 246, 2011 | 1245 | 2011 |
Genome-wide scan reveals association of psoriasis with IL-23 and NF-κB pathways RP Nair, KC Duffin, C Helms, J Ding, PE Stuart, D Goldgar, ... Nature genetics 41 (2), 199, 2009 | 1209 | 2009 |
XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease A Kaser, AH Lee, A Franke, JN Glickman, S Zeissig, H Tilg, ... Cell 134 (5), 743-756, 2008 | 1134 | 2008 |
Microbial exposure during early life has persistent effects on natural killer T cell function T Olszak, D An, S Zeissig, MP Vera, J Richter, A Franke, JN Glickman, ... Science 336 (6080), 489-493, 2012 | 1108 | 2012 |
New loci associated with kidney function and chronic kidney disease A Köttgen, C Pattaro, CA Böger, C Fuchsberger, M Olden, NL Glazer, ... Nature genetics 42 (5), 376, 2010 | 941* | 2010 |
New loci associated with kidney function and chronic kidney disease A Köttgen, C Pattaro, CA Böger, C Fuchsberger, M Olden, NL Glazer, ... Nature genetics 42 (5), 376, 2010 | 941* | 2010 |
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations JZ Liu, S Van Sommeren, H Huang, SC Ng, R Alberts, A Takahashi, ... Nature genetics 47 (9), 979, 2015 | 922 | 2015 |
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis AH Beecham, NA Patsopoulos, DK Xifara, MF Davis, A Kemppinen, ... Nature genetics 45 (11), 1353, 2013 | 737 | 2013 |
Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity LC Tsoi, SL Spain, J Knight, E Ellinghaus, PE Stuart, F Capon, J Ding, ... Nature genetics 44 (12), 1341, 2012 | 670 | 2012 |
Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease MA Rivas, M Beaudoin, A Gardet, C Stevens, Y Sharma, CK Zhang, ... Nature genetics 43 (11), 1066, 2011 | 647 | 2011 |
The dynamic genome of Hydra JA Chapman, EF Kirkness, O Simakov, SE Hampson, T Mitros, ... Nature 464 (7288), 592, 2010 | 631 | 2010 |
Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility A Franke, T Balschun, TH Karlsen, J Sventoraityte, S Nikolaus, G Mayr, ... Nature genetics 40 (11), 1319, 2008 | 596 | 2008 |
Meta-analysis and imputation refines the association of 15q25 with smoking quantity JZ Liu, F Tozzi, DM Waterworth, SG Pillai, P Muglia, L Middleton, ... Nature genetics 42 (5), 436, 2010 | 571 | 2010 |
15q13. 3 microdeletions increase risk of idiopathic generalized epilepsy I Helbig, HC Mefford, AJ Sharp, M Guipponi, M Fichera, A Franke, ... Nature genetics 41 (2), 160, 2009 | 537 | 2009 |