| Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth KM Nieman, HA Kenny, CV Penicka, A Ladanyi, R Buell-Gutbrod, ... Nature medicine 17 (11), 1498-1503, 2011 | 2190 | 2011 |
| MicroRNAs reprogram normal fibroblasts into cancer-associated fibroblasts in ovarian cancer AK Mitra, M Zillhardt, Y Hua, P Tiwari, AE Murmann, ME Peter, E Lengyel Cancer discovery 2 (12), 1100-1108, 2012 | 396 | 2012 |
| Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts MA Eckert, F Coscia, A Chryplewicz, JW Chang, KM Hernandez, S Pan, ... Nature 569 (7758), 723-728, 2019 | 358 | 2019 |
| Fibroblasts mobilize tumor cell glycogen to promote proliferation and metastasis M Curtis, HA Kenny, B Ashcroft, A Mukherjee, A Johnson, Y Zhang, ... Cell metabolism 29 (1), 141-155. e9, 2019 | 235 | 2019 |
| Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status F Coscia, KM Watters, M Curtis, MA Eckert, CY Chiang, S Tyanova, ... Nature Communications 7, 12645, 2016 | 205 | 2016 |
| Let‐7 modulates acquired resistance of ovarian cancer to Taxanes via IMP‐1‐mediated stabilization of multidrug resistance 1 B Boyerinas, SM Park, AE Murmann, K Gwin, AG Montag, M Zillhardt, ... International journal of cancer 130 (8), 1787-1797, 2012 | 190 | 2012 |
| Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy HA Kenny, M Lal-Nag, EA White, M Shen, CY Chiang, AK Mitra, Y Zhang, ... Nature communications 6 (1), 6220, 2015 | 185 | 2015 |
| Foretinib (GSK1363089), an orally available multikinase inhibitor of c-Met and VEGFR-2, blocks proliferation, induces anoikis, and impairs ovarian cancer metastasis M Zillhardt, SM Park, IL Romero, K Sawada, A Montag, T Krausz, ... Clinical Cancer Research 17 (12), 4042-4051, 2011 | 147 | 2011 |
| Multi-level proteomics identifies CT45 as a chemosensitivity mediator and immunotherapy target in ovarian cancer F Coscia, E Lengyel, J Duraiswamy, B Ashcroft, M Bassani-Sternberg, ... Cell 175 (1), 159-170. e16, 2018 | 141 | 2018 |
| β3-integrin expression on tumor cells inhibits tumor progression, reduces metastasis, and is associated with a favorable prognosis in patients with ovarian cancer S Kaur, HA Kenny, S Jagadeeswaran, MR Zillhardt, AG Montag, E Kistner, ... The American journal of pathology 175 (5), 2184-2196, 2009 | 90 | 2009 |
| An orally available small-molecule inhibitor of c-Met, PF-2341066, reduces tumor burden and metastasis in a preclinical model of ovarian cancer metastasis M Zillhardt, JG Christensen, E Lengyel Neoplasia 12 (1), 1-10, 2010 | 85 | 2010 |
| SPHK1 is a novel target of metformin in ovarian cancer PC Hart, T Chiyoda, X Liu, M Weigert, M Curtis, CY Chiang, R Loth, ... Molecular Cancer Research 17 (4), 870-881, 2019 | 59 | 2019 |
| Inhibition of glycolysis in the presence of antigen generates suppressive antigen-specific responses and restrains rheumatoid arthritis in mice JL Mangal, S Inamdar, T Le, X Shi, M Curtis, H Gu, AP Acharya Biomaterials 277, 121079, 2021 | 37 | 2021 |
| Metabolite releasing polymers control dendritic cell function by modulating their energy metabolism JL Mangal, S Inamdar, Y Yang, S Dutta, M Wankhede, X Shi, H Gu, ... Journal of Materials Chemistry B 8 (24), 5195-5203, 2020 | 31 | 2020 |
| Secretion of MCP-1 and other paracrine factors in a novel tumor-bone coculture model KR Schiller, MR Zillhardt, J Alley, DL Borjesson, AJ Beitz, LJ Mauro BMC cancer 9, 1-17, 2009 | 27 | 2009 |
| The Tumor Microenvironment Takes Center Stage in Ovarian Cancer Metastasis M Curtis, A Mukherjee, E Lengyel Trends in Cancer, 2018 | 20 | 2018 |
| Cloning and functional expression of voltage-gated ion channel subunits from cnidocytes of the Portuguese Man O'War Physalia physalis C Bouchard, RB Price, CG Moneypenny, LF Thompson, M Zillhardt, ... Journal of experimental biology 209 (15), 2979-2989, 2006 | 20 | 2006 |
| PP4 inhibition sensitizes ovarian cancer to NK cell-mediated cytotoxicity via STAT1 activation and inflammatory signaling R Raja, C Wu, EY Bassoy, TE Rubino Jr, EC Utagawa, PM Magtibay, ... Journal for Immunotherapy of Cancer 10 (12), 2022 | 7 | 2022 |
| Succinate in the tumor microenvironment affects tumor growth and modulates tumor associated macrophages S Inamdar, AP Suresh, JL Mangal, ND Ng, A Sundem, HS Behbahani, ... Biomaterials 301, 122292, 2023 | 5 | 2023 |
| Rescue of dendritic cells from glycolysis inhibition improves cancer immunotherapy in mice S Inamdar, AP Suresh, JL Mangal, ND Ng, A Sundem, C Wu, K Lintecum, ... Nature communications 14 (1), 5333, 2023 | 4 | 2023 |
Ernst LengyelProfessor of Gynecologic Oncology, University of ChicagoBestätigte E-Mail-Adresse bei uchicago.edu
