| The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair CS Sørensen, LT Hansen, J Dziegielewski, RG Syljuåsen, C Lundin, ... Nature cell biology 7 (2), 195-201, 2005 | 749 | 2005 |
| Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A CS Sørensen, RG Syljuåsen, J Falck, T Schroeder, L Rönnstrand, ... Cancer cell 3 (3), 247-258, 2003 | 718 | 2003 |
| Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage RG Syljuåsen, CS Sørensen, LT Hansen, K Fugger, C Lundin, ... Molecular and cellular biology, 2005 | 635 | 2005 |
| Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization BO Petersen, J Lukas, CS Sørensen, J Bartek, K Helin The EMBO journal, 1999 | 557 | 1999 |
| Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation M Gatei, K Sloper, C Sorensen, R Syljuäsen, J Falck, K Hobson, ... Journal of Biological Chemistry 278 (17), 14806-14811, 2003 | 424 | 2003 |
| E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APCCdh1 JY Hsu, JDR Reimann, CS Sørensen, J Lukas, PK Jackson Nature cell biology 4 (5), 358-366, 2002 | 416 | 2002 |
| Histone H4 lysine 20 methylation: key player in epigenetic regulation of genomic integrity S Jørgensen, G Schotta, CS Sørensen Nucleic acids research 41 (5), 2797-2806, 2013 | 412 | 2013 |
| Hereditary breast and ovarian cancer: new genes in confined pathways FC Nielsen, T van Overeem Hansen, CS Sørensen Nature Reviews Cancer 16 (9), 599-612, 2016 | 408 | 2016 |
| Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex C Lukas, CS Sørensen, E Kramer, E Santoni-Rugiu, C Lindeneg, ... Nature 401 (6755), 815-818, 1999 | 379 | 1999 |
| Safeguarding genome integrity: the checkpoint kinases ATR, CHK1 and WEE1 restrain CDK activity during normal DNA replication CS Sørensen, RG Syljuåsen Nucleic acids research 40 (2), 477-486, 2012 | 353 | 2012 |
| Cyclin-dependent kinase suppression by WEE1 kinase protects the genome through control of replication initiation and nucleotide consumption H Beck, V Nähse-Kumpf, MSY Larsen, KA O'Hanlon, S Patzke, ... Molecular and cellular biology 32 (20), 4226-4236, 2012 | 317 | 2012 |
| Exploiting replicative stress to treat cancer M Dobbelstein, CS Sørensen Nature reviews Drug discovery 14 (6), 405-423, 2015 | 295 | 2015 |
| Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing P Galanos, K Vougas, D Walter, A Polyzos, A Maya-Mendoza, ... Nature cell biology 18 (7), 777-789, 2016 | 278 | 2016 |
| The histone methyltransferase SET8 is required for S-phase progression S Jørgensen, I Elvers, MB Trelle, T Menzel, M Eskildsen, ON Jensen, ... The Journal of cell biology 179 (7), 1337-1345, 2007 | 228 | 2007 |
| LEDGF (p75) promotes DNA-end resection and homologous recombination M Daugaard, A Baude, K Fugger, LK Povlsen, H Beck, CS Sørensen, ... Nature structural & molecular biology 19 (8), 803-810, 2012 | 216 | 2012 |
| Regulators of cyclin-dependent kinases are crucial for maintaining genome integrity in S phase H Beck, V Nähse, MSY Larsen, P Groth, T Clancy, M Lees, M Jørgensen, ... Journal of cell biology 188 (5), 629-638, 2010 | 186 | 2010 |
| The caspase‐activated DN ase: apoptosis and beyond BD Larsen, CS Sørensen The FEBS journal 284 (8), 1160-1170, 2017 | 182 | 2017 |
| A conserved cyclin-binding domain determines functional interplay between anaphase-promoting complex–Cdh1 and cyclin A-Cdk2 during cell cycle progression CS Sørensen, C Lukas, ER Kramer, JM Peters, J Bartek, J Lukas Molecular and cellular biology 21 (11), 3692-3703, 2001 | 172 | 2001 |
| ATR, Claspin and the Rad9-Rad1-Hus1 complex regulate Chk1 and Cdc25A in the absence of DNA damage CS Sørensen, RG Syljuåsen, J Lukas, J Bartek Cell cycle 3 (7), 939-943, 2004 | 165 | 2004 |
| NEK11 regulates CDC25A degradation and the IR-induced G2/M checkpoint M Melixetian, DK Klein, CS Sørensen, K Helin Nature cell biology 11 (10), 1247-1253, 2009 | 148 | 2009 |
