Christian Schlein
Christian Schlein
MD, PhD, Junior Group Leader at University Medical Center Hamburg Eppendorf
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Zitiert von
Zitiert von
Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development
JFP Berbée, MR Boon, PPSJ Khedoe, A Bartelt, C Schlein, A Worthmann, ...
Nature communications 6 (1), 1-11, 2015
The cold-induced lipokine 12, 13-diHOME promotes fatty acid transport into brown adipose tissue
MD Lynes, LO Leiria, M Lundh, A Bartelt, F Shamsi, TL Huang, ...
Nature medicine 23 (5), 631-637, 2017
FGF21 lowers plasma triglycerides by accelerating lipoprotein catabolism in white and brown adipose tissues
C Schlein, S Talukdar, M Heine, AW Fischer, LM Krott, SK Nilsson, ...
Cell metabolism 23 (3), 441-453, 2016
Cold-induced conversion of cholesterol to bile acids in mice shapes the gut microbiome and promotes adaptive thermogenesis
A Worthmann, C John, MC Rühlemann, M Baguhl, FA Heinsen, ...
Nature medicine 23 (7), 839, 2017
Exosomal microRNA miR-92a concentration in serum reflects human brown fat activity
Y Chen, JJ Buyel, MJW Hanssen, F Siegel, R Pan, J Naumann, M Schell, ...
Nature communications 7 (1), 1-9, 2016
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
A Bartelt, SB Widenmaier, C Schlein, K Johann, RLS Goncalves, K Eguchi, ...
Nature medicine 24 (3), 292, 2018
Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport
A Bartelt, C John, N Schaltenberg, JFP Berbée, A Worthmann, ...
Nature communications 8 (1), 1-10, 2017
Lipolysis triggers a systemic insulin response essential for efficient energy replenishment of activated brown adipose tissue in mice
M Heine, AW Fischer, C Schlein, C Jung, LG Straub, K Gottschling, ...
Cell metabolism 28 (4), 644-655. e4, 2018
Intact innervation is essential for diet-induced recruitment of brown adipose tissue
AW Fischer, C Schlein, B Cannon, J Heeren, J Nedergaard
American Journal of Physiology-Endocrinology and Metabolism 316 (3), E487-E503, 2019
Homozygosity for a partial deletion of apoprotein AV signal peptide results in intracellular missorting of the protein and chylomicronemia in a breast-fed infant
K Albers, C Schlein, K Wenner, P Lohse, A Bartelt, J Heeren, R Santer, ...
Atherosclerosis 233 (1), 97-103, 2014
FoxO transcription factors are required for hepatic HDL cholesterol clearance
SX Lee, M Heine, C Schlein, R Ramakrishnan, J Liu, G Belnavis, I Haimi, ...
The Journal of clinical investigation 128 (4), 1615-1626, 2018
Course of HEV viremia and anti-HEV IgM/IgG response in asymptomatic blood donors
C Kraef, C Schlein, J Hiller, D Westhölter, U Denzer, T Horvatits, S Peine, ...
Journal of Clinical Virology 105, 26-30, 2018
Genetic dissection of tissue-specific apolipoprotein E function for hypercholesterolemia and diet-induced obesity
T Wagner, A Bartelt, C Schlein, J Heeren
PloS one 10 (12), e0145102, 2015
Implications of thermogenic adipose tissues for metabolic health
C Schlein, J Heeren
Best Practice & Research Clinical Endocrinology & Metabolism 30 (4), 487-496, 2016
PID1 regulates insulin-dependent glucose uptake by controlling intracellular sorting of GLUT4-storage vesicles
AW Fischer, K Albers, C Schlein, F Sass, LM Krott, H Schmale, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1865 (6 …, 2019
Brown adipose tissue lipoprotein and glucose disposal is not determined by thermogenesis in uncoupling protein 1-deficient mice
AW Fischer, J Behrens, F Sass, C Schlein, M Heine, P Pertzborn, ...
Journal of Lipid Research 61 (11), 1377-1389, 2020
Effects of Pharmacological Thermogenic Adipocyte Activation on Metabolism and Atherosclerotic Plaque Regression
A Worthmann, C Schlein, JFP Berbée, PCN Rensen, J Heeren, A Bartelt
Nutrients 11 (2), 463, 2019
Thermoneutrality-induced macrophage accumulation in brown adipose tissue does not impair the tissue’s competence for cold-induced thermogenic recruitment
AW Fischer, JMA de Jong, F Sass, C Schlein, J Heeren, N Petrovic
Frontiers in endocrinology 11, 2020
TFEB deficiency attenuates mitochondrial degradation upon brown adipose tissue whitening at thermoneutrality
F Sass, C Schlein, MY Jaeckstein, P Pertzborn, M Schweizer, T Schinke, ...
Molecular Metabolism 47, 101173, 2021
Characterization of Genetic and Metabolic Somatic Events in Aortic Atherosclerotic Plaques
TJ Demal, A Worthmann, H Reichenspurner, C Detter, J Heeren, ...
The Thoracic and Cardiovascular Surgeon 69 (S 01), DGTHG-KV35, 2021
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