Multiplexed lipid dip‐pen nanolithography on subcellular scales for the templating of functional proteins and cell culture S Sekula, J Fuchs, S Weg‐Remers, P Nagel, S Schuppler, J Fragala, ... small 4 (10), 1785-1793, 2008 | 198 | 2008 |
Serum proteome profiling of metastatic breast cancer using recombinant antibody microarrays A Carlsson, C Wingren, J Ingvarsson, P Ellmark, B Baldertorp, M Fernö, ... European journal of cancer 44 (3), 472-480, 2008 | 175 | 2008 |
Detection of pancreatic cancer using antibody microarray‐based serum protein profiling J Ingvarsson, C Wingren, A Carlsson, P Ellmark, B Wahren, G Engström, ... Proteomics 8 (11), 2211-2219, 2008 | 166 | 2008 |
Identification of protein expression signatures associated with Helicobacter pylori infection and gastric adenocarcinoma using recombinant antibody microarrays P Ellmark, J Ingvarsson, A Carlsson, BS Lundin, C Wingren, ... Molecular & Cellular Proteomics 5 (9), 1638-1646, 2006 | 138 | 2006 |
The human agonistic CD40 antibody ADC-1013 eradicates bladder tumors and generates T-cell–dependent tumor immunity SM Mangsbo, S Broos, E Fletcher, N Veitonmäki, C Furebring, E Dahlén, ... Clinical Cancer Research 21 (5), 1115-1126, 2015 | 104 | 2015 |
Locally delivered CD40 agonist antibody accumulates in secondary lymphoid organs and eradicates experimental disseminated bladder cancer LC Sandin, A Orlova, E Gustafsson, P Ellmark, V Tolmachev, ... Cancer immunology research 2 (1), 80-90, 2014 | 98* | 2014 |
The CTLA-4 x OX40 bispecific antibody ATOR-1015 induces anti-tumor effects through tumor-directed immune activation AM Kvarnhammar, N Veitonmäki, K Hägerbrand, A Dahlman, KE Smith, ... Journal for immunotherapy of cancer 7, 1-14, 2019 | 95 | 2019 |
Local CTLA4 blockade effectively restrains experimental pancreatic adenocarcinoma growth in vivo LC Sandin, F Eriksson, P Ellmark, ASI Loskog, TH Tötterman, ... Oncoimmunology 3 (1), e27614, 2014 | 87 | 2014 |
Multiplex detection of surface molecules on colorectal cancers P Ellmark, L Belov, P Huang, CS Lee, MJ Solomon, DK Morgan, ... Proteomics 6 (6), 1791-1802, 2006 | 85 | 2006 |
First‐in‐human study with intratumoral administration of a CD40 agonistic antibody, ADC‐1013, in advanced solid malignancies SMM Irenaeus, D Nielsen, P Ellmark, J Yachnin, A Deronic, A Nilsson, ... International journal of cancer 145 (5), 1189-1199, 2019 | 75 | 2019 |
Local checkpoint inhibition of CTLA‐4 as a monotherapy or in combination with anti‐PD1 prevents the growth of murine bladder cancer L van Hooren, LC Sandin, I Moskalev, P Ellmark, A Dimberg, P Black, ... European journal of immunology 47 (2), 385-393, 2017 | 74 | 2017 |
Affinity and Epitope Profiling of Mouse Anti‐CD40 Monoclonal Antibodies ACM Hager, P Ellmark, CAK Borrebaeck, C Furebring Scandinavian journal of immunology 57 (6), 517-524, 2003 | 60 | 2003 |
Modulation of the CD40–CD40 ligand interaction using human anti‐CD40 single‐chain antibody fragments obtained from the n‐CoDeR phage display library P Ellmark, C Ottosson, CAK Borrebaeck, AC Malmborg Hager, ... Immunology 106 (4), 456-463, 2002 | 47 | 2002 |
Administration of low-dose combination anti-CTLA4, anti-CD137, and anti-OX40 into murine tumor or proximal to the tumor draining lymph node induces systemic tumor regression JPO Hebb, AR Mosley, F Vences-Catalán, N Rajasekaran, A Rosén, ... Cancer Immunology, Immunotherapy 67 (1), 47-60, 2018 | 38 | 2018 |
Tumor-directed immunotherapy can generate tumor-specific T cell responses through localized co-stimulation P Ellmark, SM Mangsbo, C Furebring, P Norlén, TH Tötterman Cancer Immunology, Immunotherapy 66, 1-7, 2017 | 34 | 2017 |
CD137 (4-1BB) costimulation of CD8+ T cells is more potent when provided in cis than in trans with respect to CD3-TCR stimulation I Otano, A Azpilikueta, J Glez-Vaz, M Alvarez, J Medina-Echeverz, ... Nature Communications 12 (1), 7296, 2021 | 28 | 2021 |
Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy M Georganaki, M Ramachandran, S Tuit, NG Núñez, A Karampatzakis, ... Oncoimmunology 9 (1), 1730538, 2020 | 28 | 2020 |
Synergistic augmentation of CD40-mediated activation of antigen-presenting cells by amphiphilic poly (γ-glutamic acid) nanoparticles S Broos, LC Sandin, J Apel, TH Tötterman, T Akagi, M Akashi, ... Biomaterials 33 (26), 6230-6239, 2012 | 28 | 2012 |
CD86 variants with improved affinity for CTLA-4 P Ellmark, C Furebring, E Dahlen US Patent 9,834,589, 2017 | 23 | 2017 |
Rationale and clinical development of CD40 agonistic antibodies for cancer immunotherapy K Enell Smith, A Deronic, K Hägerbrand, P Norlén, P Ellmark Expert Opinion on Biological Therapy 21 (12), 1635-1646, 2021 | 21 | 2021 |