Efficient precise knockin with a double cut HDR donor after CRISPR/Cas9-mediated double-stranded DNA cleavage JP Zhang, XL Li, GH Li, W Chen, C Arakaki, GD Botimer, D Baylink, ... Genome biology 18, 1-18, 2017 | 492 | 2017 |
Desmoglein 2 is a receptor for adenovirus serotypes 3, 7, 11 and 14 H Wang, ZY Li, Y Liu, J Persson, I Beyer, T Möller, D Koyuncu, ... Nature medicine 17 (1), 96-104, 2011 | 486 | 2011 |
High incidence of leukemia in large animals after stem cell gene therapy with a HOXB4-expressing retroviral vector XB Zhang, BC Beard, GD Trobridge, BL Wood, GE Sale, R Sud, ... The Journal of clinical investigation 118 (4), 1502-1510, 2008 | 143 | 2008 |
Different effects of sgRNA length on CRISPR-mediated gene knockout efficiency JP Zhang, XL Li, A Neises, W Chen, LP Hu, GZ Ji, JY Yu, J Xu, WP Yuan, ... Scientific reports 6 (1), 28566, 2016 | 119 | 2016 |
Highly efficient genome editing via CRISPR–Cas9 in human pluripotent stem cells is achieved by transient BCL-XL overexpression XL Li, GH Li, J Fu, YW Fu, L Zhang, W Chen, C Arakaki, JP Zhang, W Wen, ... Nucleic acids research 46 (19), 10195-10215, 2018 | 112 | 2018 |
Preclinical ex vivo expansion of cord blood hematopoietic stem and progenitor cells: duration of culture; the media, serum supplements, and growth factors used; and engraftment … AC Lam, K Li, XB Zhang, CK Li, TF Fok, AMZ Chang, AE James, ... Transfusion 41 (12), 1567-1576, 2001 | 109 | 2001 |
Efficient generation of integration-free ips cells from human adult peripheral blood using BCL-XL together with Yamanaka factors RJ Su, DJ Baylink, A Neises, JB Kiroyan, X Meng, KJ Payne, ... PloS one 8 (5), e64496, 2013 | 107 | 2013 |
Efficient reprogramming of human cord blood CD34+ cells into induced pluripotent stem cells with OCT4 and SOX2 alone X Meng, A Neises, RJ Su, KJ Payne, L Ritter, DS Gridley, J Wang, ... Molecular Therapy 20 (2), 408-416, 2012 | 106 | 2012 |
Dynamics and competition of CRISPR–Cas9 ribonucleoproteins and AAV donor-mediated NHEJ, MMEJ and HDR editing YW Fu, XY Dai, WT Wang, ZX Yang, JJ Zhao, JP Zhang, W Wen, F Zhang, ... Nucleic acids research 49 (2), 969-985, 2021 | 101 | 2021 |
Trehalose ameliorates the cryopreservation of cord blood in a preclinical system and increases the recovery of CFUs, long‐term culture‐initiating cells, and nonobese diabetic … XB Zhang, K Li, KH Yau, KS Tsang, TF Fok, CK Li, SM Lee, PMP Yuen Transfusion 43 (2), 265-272, 2003 | 89 | 2003 |
Controlled extracellular matrix degradation in breast cancer tumors improves therapy by trastuzumab I Beyer, Z Li, J Persson, Y Liu, R Van Rensburg, R Yumul, XB Zhang, ... Molecular Therapy 19 (3), 479-489, 2011 | 82 | 2011 |
Targeted genome engineering in human induced pluripotent stem cells from patients with hemophilia B using the CRISPR-Cas9 system C Lyu, J Shen, R Wang, H Gu, J Zhang, F Xue, X Liu, W Liu, R Fu, ... Stem Cell Research & Therapy 9, 1-12, 2018 | 76 | 2018 |
Cellular reprogramming of human peripheral blood cells XB Zhang Genomics, proteomics & bioinformatics 11 (5), 264-274, 2013 | 76 | 2013 |
PDGFB-based stem cell gene therapy increases bone strength in the mouse W Chen, DJ Baylink, J Brier-Jones, A Neises, JB Kiroyan, CH Rundle, ... Proceedings of the National Academy of Sciences 112 (29), E3893-E3900, 2015 | 72 | 2015 |
Platelet‐derived growth factor promotes ex vivo expansion of CD34+ cells from human cord blood and enhances long‐term culture‐initiating cells, non‐obese … RJ Su, XB Zhang, K Li, M Yang, CK Li, TF Fok, AE James, H Pong, ... British journal of haematology 117 (3), 735-746, 2002 | 69 | 2002 |
Vectors and methods for the efficient generation of integration/transgene-free induced pluripotent stem cells from peripheral blood cells DJ Baylink, KHW Lau, X Zhang US Patent 9,850,499, 2017 | 68 | 2017 |
Platelet-derived growth factor enhances ex vivo expansion of megakaryocytic progenitors from human cord blood RJ Su, K Li, M Yang, XB Zhang, KS Tsang, TF Fok, CK Li, PMP Yuen Bone marrow transplantation 27 (10), 1075-1080, 2001 | 64 | 2001 |
A new human DSG2-transgenic mouse model for studying the tropism and pathology of human adenoviruses H Wang, I Beyer, J Persson, H Song, ZY Li, M Richter, H Cao, ... Journal of virology 86 (11), 6286-6302, 2012 | 63 | 2012 |
Differential effects of HOXB4 on nonhuman primate short-and long-term repopulating cells XB Zhang, BC Beard, K Beebe, B Storer, RK Humphries, HP Kiem PLoS Medicine 3 (5), e173, 2006 | 62 | 2006 |
Generation of iPS cells from human peripheral blood mononuclear cells using episomal vectors RJ Su, A Neises, XB Zhang Induced Pluripotent Stem (iPS) Cells: Methods and Protocols, 57-69, 2016 | 59 | 2016 |