Kathrin Buchholz
Kathrin Buchholz
Research Fellow, Biochemistry and Molecular Biology, Justus Liebig University Giessen
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Interactions of Methylene Blue with Human Disulfide Reductases and Their Orthologues from Plasmodium falciparum
K Buchholz, RH Schirmer, JK Eubel, MB Akoachere, T Dandekar, ...
Antimicrobial agents and chemotherapy 52 (1), 183-191, 2008
A high-throughput screen targeting malaria transmission stages opens new avenues for drug development
K Buchholz, TA Burke, KC Williamson, RC Wiegand, DF Wirth, M Marti
Journal of Infectious Diseases 203 (10), 1445-1453, 2011
In Vitro Assessment of Methylene Blue on Chloroquine-Sensitive and -Resistant Plasmodium falciparum Strains Reveals Synergistic Action with Artemisinins
M Akoachere, K Buchholz, E Fischer, J Burhenne, WE Haefeli, ...
Antimicrobial agents and chemotherapy 49 (11), 4592-4597, 2005
Drug Screen Targeted at Plasmodium Liver Stages Identifies a Potent Multistage Antimalarial Drug
FP da Cruz, C Martin, K Buchholz, MJ Lafuente-Monasterio, T Rodrigues, ...
Journal of Infectious Diseases 205 (8), 1278-1286, 2012
Torins are potent antimalarials that block replenishment of Plasmodium liver stage parasitophorous vacuole membrane proteins
KK Hanson, AS Ressurreição, K Buchholz, M Prudêncio, ...
Proceedings of the National Academy of Sciences 110 (30), E2838-E2847, 2013
Transcriptional profiling defines dynamics of parasite tissue sequestration during malaria infection.
KG Pelle, K Oh, K Buchholz, V Narasimhan, R Joice, DA Milner, ...
Genome Med. 7 (1), 19, 2015
An assay to probe Plasmodium falciparum growth, transmission stage formation and early gametocyte development
NMB Brancucci, I Goldowitz, K Buchholz, K Werling, M Marti
Nature protocols 10 (8), 1131-1142, 2015
Molecular genetics evidence for the in vivo roles of the two major NADPH-dependent disulfide reductases in the malaria parasite
K Buchholz, ED Putrianti, S Rahlfs, RH Schirmer, K Becker, ...
Journal of biological chemistry 285 (48), 37388-37395, 2010
Cytotoxic interactions of methylene blue with trypanosomatid-specific disulfide reductases and their dithiol products
K Buchholz, MA Comini, D Wissenbach, RH Schirmer, RL Krauth-Siegel, ...
Molecular and biochemical parasitology 160 (1), 65-69, 2008
Optimization of flow cytometric detection and cell sorting of transgenic Plasmodium parasites using interchangeable optical filters
IA Vorobjev, K Buchholz, P Prabhat, K Ketman, ES Egan, M Marti, ...
Malaria Journal 11, 1-10, 2012
Stable Integration and Comparison of hGrx1-roGFP2 and sfroGFP2 Redox Probes in the Malaria Parasite Plasmodium falciparum
AK Schuh, M Rahbari, KC Heimsch, F Mohring, SJ Gabryszewski, ...
ACS infectious diseases 4 (11), 1601-1612, 2018
Depletion of Plasmodium berghei plasmoredoxin reveals a non-essential role for life cycle progression of the malaria parasite
K Buchholz, S Rahlfs, RH Schirmer, K Becker, K Matuschewski
PLoS One 3 (6), e2474, 2008
An optimized dihydrodibenzothiazepine lead compound (SBI-0797750) as a potent and selective inhibitor of Plasmodium falciparum and P. vivax glucose 6-phosphate dehydrogenase 6 …
I Berneburg, S Peddibhotla, KC Heimsch, K Haeussler, P Maloney, ...
Antimicrobial Agents and Chemotherapy 66 (4), e02109-21, 2022
Structure-based drug development against malaria
K Buchholz, B Mwongela Mailu, R Heiner Schirmer, K Becker
Frontiers in Drug Design & Discovery: Structure-Based Drug Design in the …, 2007
Redoxnetzwerke des Malariaerregers Plasmodium: Validierung von Schlüsselenzymen für neue chemotherapeutische Ansätze
K Buchholz
Functional characterization of Plasmodium redoxrelated enzymes.
K Buchholz, K Matuschewski, RH Schirmer, K Becker
Redoxnetzwerke des Malariaerregers Plasmodium: Validierung von Schlüsselenzymen für neue chemotherapeutische Ansätze
K Buchholz
Zugl.: Gießen, Univ., Diss., 2008, 0
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