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Jason Girkin
Jason Girkin
PhD of Immunology and Microbiology at the University of Newcastle
Bestätigte E-Mail-Adresse bei uon.edu.au
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Zitiert von
Zitiert von
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Corticosteroid suppression of antiviral immunity increases bacterial loads and mucus production in COPD exacerbations
A Singanayagam, N Glanville, JL Girkin, YM Ching, A Marcellini, ...
Nature communications 9 (1), 2229, 2018
1822018
Toll-like receptor 7 governs interferon and inflammatory responses to rhinovirus and is suppressed by IL-5-induced lung eosinophilia
L Hatchwell, A Collison, J Girkin, K Parsons, J Li, J Zhang, S Phipps, ...
Thorax 70 (9), 854-861, 2015
1092015
Antiviral immunity is impaired in COPD patients with frequent exacerbations
A Singanayagam, SL Loo, M Calderazzo, LJ Finney, MB Trujillo Torralbo, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 317 (6 …, 2019
612019
CCL7 and IRF-7 mediate hallmark inflammatory and IFN responses following rhinovirus 1B infection
J Girkin, L Hatchwell, P Foster, SL Johnston, N Bartlett, A Collison, ...
The Journal of Immunology 194 (10), 4924-4930, 2015
442015
Salmeterol attenuates chemotactic responses in rhinovirus-induced exacerbation of allergic airways disease by modulating protein phosphatase 2A
L Hatchwell, J Girkin, MD Dun, M Morten, N Verrills, HD Toop, JC Morris, ...
Journal of allergy and clinical immunology 133 (6), 1720-1727, 2014
422014
A critical role for the CXCL3/CXCL5/CXCR2 neutrophilic chemotactic axis in the regulation of type 2 responses in a model of rhinoviral-induced asthma exacerbation
LA Sokulsky, K Garcia-Netto, TH Nguyen, JLN Girkin, A Collison, J Mattes, ...
The Journal of Immunology 205 (9), 2468-2478, 2020
402020
TRAIL signaling is proinflammatory and proviral in a murine model of rhinovirus 1B infection
JL Girkin, LM Hatchwell, AM Collison, MR Starkey, PM Hansbro, H Yagita, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 312 (1 …, 2017
232017
TLR2-mediated innate immune priming boosts lung anti-viral immunity
J Girkin, SL Loo, C Esneau, S Maltby, F Mercuri, B Chua, AT Reid, ...
European Respiratory Journal 58 (1), 2021
202021
TLR2-mediated activation of innate responses in the upper airways confers antiviral protection of the lungs
G Deliyannis, CY Wong, HA McQuilten, A Bachem, M Clarke, X Jia, ...
JCI insight 6 (5), 2021
192021
Toll-like receptor-agonist-based therapies for respiratory viral diseases: thinking outside the cell
JLN Girkin, S Maltby, NW Bartlett
European Respiratory Review 31 (164), 2022
132022
IL-25 blockade augments antiviral immunity during respiratory virus infection
TC Williams, SL Loo, KS Nichol, AT Reid, PC Veerati, C Esneau, ...
Communications Biology 5 (1), 415, 2022
112022
ABM125 anti-IL-25 antibody pre-clinical development for viral asthma exacerbations identifies IL-25 mediated regulation of type-2-and anti-viral immunity
N Bartlett, J Girkin, T Williams, T Vincent, C Jackson, K Alton, R Shimkets
C31. MECHANISTIC INSIGHTS INTO LUNG INFECTION, A7759-A7759, 2018
52018
In vivo experimental models of infection and disease
J Girkin, S Maltby, A Singanayagam, N Bartlett, P Mallia
Rhinovirus Infections, 195-238, 2019
42019
Rhinovirus infection induces secretion of endothelin-1 from airway epithelial cells in both in vitro and in vivo models
ABC Dy, J Girkin, A Marrocco, A Collison, C Mwase, MJ O’Sullivan, ...
Respiratory Research 24 (1), 205, 2023
32023
Is CC Chemokine Ligand 17 (TARC) Driving Disease Progression in Chronic Obstructive Pulmonary Disease?
J Girkin
American Journal of Respiratory Cell and Molecular Biology 66 (4), 358-360, 2022
32022
Emerging therapeutic approaches
G McLean, J Girkin, R Solari
Rhinovirus Infections, 239-263, 2019
22019
Upper Airway TLR2 Immune Modulators Prime Broad Respiratory Immunity Against Rhinovirus and Influenza Infection and Inhibit Subsequent Lung Inflammation
NW Bartlett, J Girkin, CY Wong, G Deliyannis, W Zeng, C Demaison, ...
D107. HOST PATHOGEN INTERACTIONS, A7803-A7803, 2018
12018
Upper Respiratory Tract OC43 Infection Model for Investigating Airway Immune-Modifying Therapies
JLN Girkin, NE Bryant, SL Loo, A Hsu, A Kanwal, TC Williams, S Maltby, ...
American journal of respiratory cell and molecular biology 69 (6), 614-622, 2023
2023
Rhinovirus Infection Induces Endothelin-1 Secretion From Human Bronchial Epithelial Cells and in Mouse Models of Allergic Airway Disease
ABC Dy, J Girkin, A Marrocco, A Collison, C Mwase, MJ O'Sullivan, ...
B31. ASTHMA: FROM MICE TO MEN, AND BACK AGAIN, A3027-A3027, 2023
2023
A unique role for IL-13 in inducing esophageal eosinophilia through MID-1 and STAT6
JLN Girkin, LA Sokulsky, MR Starkey, PM Hansbro, PS Foster, ...
Frontiers in allergy 4, 2023
2023
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