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Bruno Correia
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Proteome-wide covalent ligand discovery in native biological systems
KM Backus, BE Correia, KM Lum, S Forli, BD Horning, GE González-Páez, ...
Nature 534 (7608), 570-574, 2016
7112016
Proof of principle for epitope-focused vaccine design
BE Correia, JT Bates, RJ Loomis, G Baneyx, C Carrico, JG Jardine, ...
Nature 507 (7491), 201-206, 2014
5512014
Macromolecular modeling and design in Rosetta: recent methods and frameworks
JK Leman, BD Weitzner, SM Lewis, J Adolf-Bryfogle, N Alam, RF Alford, ...
Nature methods 17 (7), 665-680, 2020
5502020
Deciphering interaction fingerprints from protein molecular surfaces using geometric deep learning
P Gainza, F Sverrisson, F Monti, E Rodola, D Boscaini, MM Bronstein, ...
Nature Methods 17 (2), 184-192, 2020
5412020
Global profiling of lysine reactivity and ligandability in the human proteome
SM Hacker, KM Backus, MR Lazear, S Forli, BE Correia, BF Cravatt
Nature chemistry 9 (12), 1181-1190, 2017
3682017
Ligand and target discovery by fragment-based screening in human cells
CG Parker, A Galmozzi, Y Wang, BE Correia, K Sasaki, CM Joslyn, ...
Cell 168 (3), 527-541. e29, 2017
3662017
Solution structure of a minor and transiently formed state of a T4 lysozyme mutant
G Bouvignies, P Vallurupalli, DF Hansen, BE Correia, O Lange, A Bah, ...
Nature 477 (7362), 111-114, 2011
3072011
Computational design of epitope-scaffolds allows induction of antibodies specific for a poorly immunogenic HIV vaccine epitope
BE Correia, YEA Ban, MA Holmes, H Xu, K Ellingson, Z Kraft, C Carrico, ...
Structure 18 (9), 1116-1126, 2010
2562010
Computation-guided backbone grafting of a discontinuous motif onto a protein scaffold
ML Azoitei, BE Correia, YEA Ban, C Carrico, O Kalyuzhniy, L Chen, ...
Science 334 (6054), 373-376, 2011
2462011
Scaffolding protein functional sites using deep learning
J Wang, S Lisanza, D Juergens, D Tischer, JL Watson, KM Castro, ...
Science 377 (6604), 387-394, 2022
2252022
A global map of lipid-binding proteins and their ligandability in cells
MJ Niphakis, KM Lum, AB Cognetta, BE Correia, TA Ichu, J Olucha, ...
Cell 161 (7), 1668-1680, 2015
2122015
Engineered anti-CRISPR proteins for optogenetic control of CRISPR–Cas9
F Bubeck, MD Hoffmann, Z Harteveld, S Aschenbrenner, A Bietz, ...
Nature methods 15 (11), 924-927, 2018
1952018
Optimization of therapeutic antibodies by predicting antigen specificity from antibody sequence via deep learning
DM Mason, S Friedensohn, CR Weber, C Jordi, B Wagner, SM Meng, ...
Nature Biomedical Engineering 5 (6), 600-612, 2021
1752021
De novo protein design enables the precise induction of RSV-neutralizing antibodies
F Sesterhenn, C Yang, J Bonet, JT Cramer, X Wen, Y Wang, CI Chiang, ...
Science 368 (6492), eaay5051, 2020
1442020
A computationally designed inhibitor of an Epstein-Barr viral Bcl-2 protein induces apoptosis in infected cells
E Procko, GY Berguig, BW Shen, Y Song, S Frayo, AJ Convertine, ...
Cell 157 (7), 1644-1656, 2014
1402014
Design and characterization of epitope-scaffold immunogens that present the motavizumab epitope from respiratory syncytial virus
JS McLellan, BE Correia, M Chen, Y Yang, BS Graham, WR Schief, ...
Journal of molecular biology 409 (5), 853-866, 2011
1202011
Fast end-to-end learning on protein surfaces
F Sverrisson, J Feydy, BE Correia, MM Bronstein
Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern …, 2021
1162021
A computationally designed chimeric antigen receptor provides a small-molecule safety switch for T-cell therapy
G Giordano-Attianese, P Gainza, E Gray-Gaillard, E Cribioli, S Shui, S Kim, ...
Nature Biotechnology 38 (4), 426-432, 2020
1132020
Mapping the protein interaction landscape for fully functionalized small-molecule probes in human cells
T Kambe, BE Correia, MJ Niphakis, BF Cravatt
Journal of the American Chemical Society 136 (30), 10777-10782, 2014
1112014
Antibodies to combat viral infections: development strategies and progress
G Pantaleo, B Correia, C Fenwick, VS Joo, L Perez
Nature Reviews Drug Discovery 21 (9), 676-696, 2022
832022
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Articles 1–20