| Unlocking P (V): Reagents for chiral phosphorothioate synthesis KW Knouse, JN deGruyter, MA Schmidt, B Zheng, JC Vantourout, ... Science 361 (6408), 1234-1238, 2018 | 186 | 2018 |
| Quinuclidine compounds as α-7 nicotinic acetylcholine receptor ligands IIJH Cook, IM McDonald, D King, RE Olson, N Wang, CI Iwuagwu, FC Zusi, ... US Patent 8,309,577, 2012 | 84 | 2012 |
| An expeditious approach toward the total synthesis of CP-263,114 JT Njardarson, IM McDonald, DA Spiegel, M Inoue, JL Wood Organic Letters 3 (16), 2435-2438, 2001 | 73 | 2001 |
| The art of innovation in organic chemistry: Synthetic efforts toward the phomoidrides DA Spiegel, JT Njardarson, IM McDonald, JL Wood Chemical reviews 103 (7), 2691-2728, 2003 | 54 | 2003 |
| Nature chose phosphates and chemists should too: How emerging P (V) methods can augment existing strategies KW Knouse, DT Flood, JC Vantourout, MA Schmidt, IM Mcdonald, ... ACS Central Science 7 (9), 1473-1485, 2021 | 49 | 2021 |
| AP (V) platform for oligonucleotide synthesis Y Huang, KW Knouse, S Qiu, W Hao, NM Padial, JC Vantourout, B Zheng, ... Science 373 (6560), 1265-1270, 2021 | 45 | 2021 |
| Tandem ring-closing metathesis/transfer hydrogenation: practical chemoselective hydrogenation of alkenes T Connolly, Z Wang, MA Walker, IM McDonald, KM Peese Organic letters 16 (17), 4444-4447, 2014 | 43 | 2014 |
| Quinuclidine compounds as alpha-7 nicotinic acetylcholine receptor ligands IIJH Cook, IM McDonald, D King, RE Olson, N Wang, CI Iwuagwu, FC Zusi, ... US Patent 7,863,291, 2011 | 38 | 2011 |
| Effect of alpha7 nicotinic acetylcholine receptor agonists on attentional set-shifting impairment in rats KM Jones, IM McDonald, C Bourin, RE Olson, LJ Bristow, A Easton Psychopharmacology 231, 673-683, 2014 | 34 | 2014 |
| Total Synthesis of (±)‐Phomoidride D JC Leung, AA Bedermann, JT Njardarson, DA Spiegel, GK Murphy, ... Angewandte Chemie International Edition 57 (7), 1991-1994, 2018 | 32 | 2018 |
| General Method for the Preparation of Electron-Deficient Imidazo[1,2-a]pyridines and Related Heterocycles IM McDonald, KM Peese Organic letters 17 (24), 6002-6005, 2015 | 30 | 2015 |
| Effects of BMS-902483, an α7 nicotinic acetylcholine receptor partial agonist, on cognition and sensory gating in relation to receptor occupancy in rodents RL Pieschl, R Miller, KM Jones, DJ Post-Munson, P Chen, K Newberry, ... European Journal of Pharmacology 807, 1-11, 2017 | 22 | 2017 |
| Discovery of a novel series of quinolone α7 nicotinic acetylcholine receptor agonists IM McDonald, RA Mate, FC Zusi, H Huang, DJ Post-Munson, MA Ferrante, ... Bioorganic & medicinal chemistry letters 23 (6), 1684-1688, 2013 | 22 | 2013 |
| B-973, a novel piperazine positive allosteric modulator of the α7 nicotinic acetylcholine receptor DJ Post-Munson, RL Pieschl, TF Molski, JD Graef, AW Hendricson, ... European Journal of Pharmacology 799, 16-25, 2017 | 21 | 2017 |
| Toward the synthesis of phomoidride D GK Murphy, T Shirahata, N Hama, A Bedermann, P Dong, TC McMahon, ... The Journal of Organic Chemistry 78 (2), 477-489, 2013 | 20 | 2013 |
| Heteroarylene-bridged benzodiazepine dimers, conjugates thereof, and methods of making and using IM McDonald, NS Chowdari, WL Johnson, Y Zhang, RM Borzilleri, ... US Patent 9,526,801, 2016 | 18 | 2016 |
| Design and Synthesis of a New Series of 4-Heteroarylamino-1′-azaspiro [oxazole-5, 3′-bicyclo [2.2. 2] octanes as α7 Nicotinic Receptor Agonists. 1. Development of … J Cook, FC Zusi, IM McDonald, D King, MD Hill, C Iwuagwu, RA Mate, ... Journal of Medicinal Chemistry 59 (24), 11171-11181, 2016 | 14 | 2016 |
| Development of 4-Heteroarylamino-1′-azaspiro [oxazole-5, 3′-bicyclo [2.2. 2] octanes] as α7 Nicotinic Receptor Agonists MD Hill, H Fang, HD King, CI Iwuagwu, IM McDonald, J Cook, FC Zusi, ... ACS Medicinal Chemistry Letters 8 (1), 133-137, 2017 | 12 | 2017 |
| Highly Strained para-phenylene-bridged macrocycles from unstrained 1, 4-diketo macrocycles NK Mitra, CP Merryman, BL Merner Synlett 28 (17), 2205-2211, 2017 | 11 | 2017 |
| BMS-933043, a Selective α7 nAChR partial agonist for the treatment of cognitive deficits associated with schizophrenia D King, C Iwuagwu, J Cook, IM McDonald, R Mate, FC Zusi, MD Hill, ... ACS Medicinal Chemistry Letters 8 (3), 366-371, 2017 | 11 | 2017 |
