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Tao-Hsin Chang
Tao-Hsin Chang
Research Specialist, Howard Hughes Medical Institute
Bestätigte E-Mail-Adresse bei ntu.edu.tw
Titel
Zitiert von
Zitiert von
Jahr
Notum deacylates Wnt proteins to suppress signalling activity
S Kakugawa, PF Langton, M Zebisch, SA Howell, TH Chang, Y Liu, ...
Nature 519 (7542), 187-192, 2015
4052015
Bisphosphonates target multiple sites in both cis-and trans-prenyltransferases
RT Guo, R Cao, PH Liang, TP Ko, TH Chang, MP Hudock, WY Jeng, ...
Proceedings of the National Academy of Sciences 104 (24), 10022-10027, 2007
2212007
Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan
TH Chang, FL Hsieh, M Zebisch, K Harlos, J Elegheert, EY Jones
Elife 4, e06554, 2015
1222015
Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation
TH Chang, FL Hsieh, TP Ko, KH Teng, PH Liang, AHJ Wang
The Plant Cell 22 (2), 454-467, 2010
1222010
Crystal structure of type-III geranylgeranyl pyrophosphate synthase from Saccharomyces cerevisiae and the mechanism of product chain length determination
TH Chang, RT Guo, TP Ko, AHJ Wang, PH Liang
Journal of Biological Chemistry 281 (21), 14991-15000, 2006
1112006
Inhibition of Geranylgeranyl Diphosphate Synthase by Bisphosphonates: A Crystallographic and Computational Investigation†
MP Hudock, Y Zhang, RT Guo, R Cao, JH No, PH Liang, TP Ko, ...
Journal of medicinal chemistry 51 (18), 5594-5607, 2008
932008
Structure and mechanism of an Arabidopsis medium/long-chain-length prenyl pyrophosphate synthase
FL Hsieh, TH Chang, TP Ko, AHJ Wang
Plant physiology 155 (3), 1079-1090, 2011
902011
Crystal structure of vaccinia viral A27 protein reveals a novel structure critical for its function and complex formation with A26 protein
TH Chang, SJ Chang, FL Hsieh, TP Ko, CT Lin, MR Ho, I Wang, STD Hsu, ...
PLoS pathogens 9 (8), e1003563, 2013
412013
Structure of the RECK CC domain, an evolutionary anomaly
TH Chang, FL Hsieh, PM Smallwood, SB Gabelli, J Nathans
Proceedings of the National Academy of Sciences 117 (26), 15104-15111, 2020
122020
Structural insights into plasmalemma vesicle-associated protein (PLVAP): Implications for vascular endothelial diaphragms and fenestrae
TH Chang, FL Hsieh, X Gu, PM Smallwood, JM Kavran, SB Gabelli, ...
Proceedings of the National Academy of Sciences 120 (14), e2221103120, 2023
72023
Antibody Display of cell surface receptor Tetraspanin12 and SARS-CoV-2 spike protein
FL Hsieh, TH Chang
bioRxiv, 2021.05. 29.446300, 2021
52021
Enhanced specificity of mint geranyl pyrophosphate synthase by modifying the R-loop interactions
FL Hsieh, TH Chang, TP Ko, AHJ Wang
Journal of molecular biology 404 (5), 859-873, 2010
52010
Control Activity of Yeast Geranylgeranyl Diphosphate Synthase from Dimer Interface through H-Bonds and Hydrophobic Interaction
CK Chang, KH Teng, SW Lin, TH Chang, PH Liang
Biochemistry 52 (16), 2783-2792, 2013
32013
Structure of WNT inhibitor adenomatosis polyposis coli down-regulated 1 (APCDD1), a cell-surface lipid-binding protein
FL Hsieh, TH Chang, SB Gabelli, J Nathans
Proceedings of the National Academy of Sciences 120 (20), e2217096120, 2023
12023
Structural insights into Frizzled assembly by acylated Wnt and Frizzled Connector domain
TH Chang, FL Hsieh, K Harlos, EY Jones
bioRxiv, 2022.09. 29.510206, 2022
12022
Structural basis of Norrin recognition by Lgr4/5/6
TH Chang, K Harlos, FL Hsieh, EY Jones
bioRxiv, 2022.09. 29.510199, 2022
12022
Antibody Display Technology (ADbody) to Present Challenging and Unstable Target Proteins on Antibodies
FL Hsieh, TH Chang
Genotype Phenotype Coupling: Methods and Protocols, 373-382, 2023
2023
Native SAD data collection using microbeam at NSLSII
K Phan, W Shi, T Chang, T Aytenfisu, A Soares, J Jakoncic, ...
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES 76, A58-A58, 2020
2020
Structural and Functional Insights of Norrin Mimics Wnt for Signalling
TH Chang, FL Hsieh, M Zebisch, K Harlos, J Elegheert, EY Jones
Biophysical Journal 110 (3), 590a, 2016
2016
Crystal structure of a bifunctional heterotetrameric terpene synthase: functional switchviaprotein-protein interaction
TH Chang, FL Hsieh, TP Ko, RT Guo, PH Liang, AHJ Wang
Acta Crystallographica Section A 65, s129-s129, 2009
2009
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